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Journal Abstract Search

116 related items for PubMed ID: 1872946

  • 1. Aziridinyl nitropyrroles and nitropyrazoles as hypoxia-selective cytotoxins and radiosensitizers.
    Naylor MA, Stephens MA, Stratford IJ, Keohane A, O'Neill P, Threadgill MD, Webb P, Fielden EM, Adams GE.
    Anticancer Drug Des; 1991 Jul; 6(3):151-67. PubMed ID: 1872946
    [Abstract] [Full Text] [Related]

  • 2. 2-Nitroimidazole dual-function bioreductive drugs: studies on the effects of regioisomerism and side-chain structural modifications on differential cytotoxicity and radiosensitization by aziridinyl and oxiranyl derivatives.
    Naylor MA, Threadgill MD, Webb P, Stratford IJ, Stephens MA, Fielden EM, Adams GE.
    J Med Chem; 1992 Sep 18; 35(19):3573-8. PubMed ID: 1404237
    [Abstract] [Full Text] [Related]

  • 3. Assessment of a range of novel nitro-aromatic radiosensitizers and bioreductive drugs.
    Fielden EM, Adams GE, Cole S, Naylor MA, O'Neill P, Stephens MA, Stratford IJ.
    Int J Radiat Oncol Biol Phys; 1992 Sep 18; 22(4):707-11. PubMed ID: 1544842
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of novel electrophilic nitrofuran carboxamides and carboxylates as radiosensitizers and bioreductively activated cytotoxins.
    Naylor MA, Stephens MA, Cole S, Threadgill MD, Stratford IJ, O'Neill P, Fielden EM, Adams GE.
    J Med Chem; 1990 Sep 18; 33(9):2508-13. PubMed ID: 2391690
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and evaluation of alpha-[[(2-haloethyl)amino]methyl]-2- nitro-1H-imidazole-1-ethanols as prodrugs of alpha-[(1-aziridinyl)methyl]-2- nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins.
    Jenkins TC, Naylor MA, O'Neill P, Threadgill MD, Cole S, Stratford IJ, Adams GE, Fielden EM, Suto MJ, Stier MA.
    J Med Chem; 1990 Sep 18; 33(9):2603-10. PubMed ID: 2391699
    [Abstract] [Full Text] [Related]

  • 6. Electron affinic sensitization. V. Radiosensitization of hypoxic bacteria and mammalian cells in vitro by some nitroimidazoles and nitropyrazoles.
    Asquith JC, Watts ME, Patel K, Smithen CE, Adams GE.
    Radiat Res; 1974 Oct 18; 60(1):108-18. PubMed ID: 10881704
    [No Abstract] [Full Text] [Related]

  • 7. 3-Nitro-1,2,4-triazoles as hypoxia-selective agents.
    Jenkins TC, Stratford IJ, Stephens MA.
    Anticancer Drug Des; 1989 Aug 18; 4(2):145-60. PubMed ID: 2803463
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of potential dual-acting radiation sensitizer antineoplastic agents: 2,2-dimethylphosphoraziridines containing 2-nitroimidazoles or other electron-affinic moieties.
    Perlman ME, Dunn JA, Piscitelli TA, Earle J, Rose WC, Wampler GL, MacDiarmid JE, Bardos TJ.
    J Med Chem; 1991 Apr 18; 34(4):1400-7. PubMed ID: 2016716
    [Abstract] [Full Text] [Related]

  • 9. Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: a new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers.
    Hay MP, Wilson WR, Moselen JW, Palmer BD, Denny WA.
    J Med Chem; 1994 Feb 04; 37(3):381-91. PubMed ID: 8308864
    [Abstract] [Full Text] [Related]

  • 10. Abnormal radiosensitizing and cytotoxic properties of ortho-substituted nitroimidazoles.
    Stratford IJ, Hoe S, Adams GE, Hardy C, Williamson C.
    Int J Radiat Biol Relat Stud Phys Chem Med; 1983 Jan 04; 43(1):31-43. PubMed ID: 6601069
    [Abstract] [Full Text] [Related]

  • 11. Proceedings: Sensitization of hypoxic mammalian cells in vitro by some nitroimidazoles and nitropyrazoles.
    Asquith JC, Watts M.
    Br J Radiol; 1975 Jan 04; 48(565):75. PubMed ID: 1109646
    [No Abstract] [Full Text] [Related]

  • 12. Cytotoxic properties of a 4-nitroimidazole (NSC 38087): a radiosensitizer of hypoxic cells in vitro.
    Stratford IJ, Williamson C, Hardy C.
    Br J Cancer; 1981 Jul 04; 44(1):109-16. PubMed ID: 7259957
    [Abstract] [Full Text] [Related]

  • 13. 2-Arylidene-4-cyclopentene-1,3-diones designed as non-nitro radiosensitizers and hypoxic cytotoxins.
    Hori H, Maezawa H, Iitaka Y, Ohsaka T, Shibata T, Mori T, Inayama S.
    Jpn J Cancer Res; 1987 Oct 04; 78(10):1128-33. PubMed ID: 3119546
    [Abstract] [Full Text] [Related]

  • 14. A new class of analogues of the bifunctional radiosensitizer alpha-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines.
    Suto MJ, Stier MA, Werbel LM, Arundel-Suto CM, Leopold WR, Elliott WE, Sebolt-Leopold JS.
    J Med Chem; 1991 Aug 04; 34(8):2484-8. PubMed ID: 1875345
    [Abstract] [Full Text] [Related]

  • 15. Electron-affinic radiosensitizers possessing NPSH-reactive side chains: cytotoxicity and radiosensitizing activity towards hypoxic EMT6 cells in vitro.
    Zhou L, Nishimoto S.
    Int J Radiat Biol; 1995 Mar 04; 67(3):335-46. PubMed ID: 7897282
    [Abstract] [Full Text] [Related]

  • 16. Chloronitroimidazoles as radiosensitizers of hypoxic cells in vitro.
    Wideł M, Watras J, Suwiński J, Salwińska E.
    Neoplasma; 1987 Mar 04; 34(3):241-51. PubMed ID: 3614460
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxins.
    Threadgill MD, Webb P, O'Neill P, Naylor MA, Stephens MA, Stratford IJ, Cole S, Adams GE, Fielden EM.
    J Med Chem; 1991 Jul 04; 34(7):2112-20. PubMed ID: 2066984
    [Abstract] [Full Text] [Related]

  • 18. 5-substituted analogues of 3-hydroxymethyl-5-aziridinyl-1-methyl-2-[1H-indole-4,7-dione]prop-2-en- 1-ol (EO9, NSC 382459) and their regioisomers as hypoxia-selective agents: structure-cytotoxicity in vitro.
    Jaffar M, Naylor MA, Robertson N, Lockyer SD, Phillips RM, Everett SA, Adams GE, Stratford IJ.
    Anticancer Drug Des; 1998 Mar 04; 13(2):105-23. PubMed ID: 9524554
    [Abstract] [Full Text] [Related]

  • 19. Radiosensitizing ability and cytotoxicity of some 5(4)-substituted 2-methyl-4(5)-nitroimidazoles.
    Wideł M, Watras J, Suwiński J, Salwińska E.
    Neoplasma; 1982 Mar 04; 29(4):407-15. PubMed ID: 7133232
    [Abstract] [Full Text] [Related]

  • 20. Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential.
    Adams GE, Stratford IJ, Wallace RG, Wardman P, Watts ME.
    J Natl Cancer Inst; 1980 Mar 04; 64(3):555-60. PubMed ID: 6928241
    [Abstract] [Full Text] [Related]

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