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Journal Abstract Search

109 related items for PubMed ID: 1875914

  • 1. Role of the steroid 17 alpha-hydroxylase in spironolactone-mediated destruction of adrenal cytochrome P-450.
    Kossor DC, Kominami S, Takemori S, Colby HD.
    Mol Pharmacol; 1991 Aug; 40(2):321-5. PubMed ID: 1875914
    [Abstract] [Full Text] [Related]

  • 2. Relationship between covalent binding to microsomal protein and the destruction of adrenal cytochrome P-450 by spironolactone.
    Colby HD, O'Donnell JP, Flowers NL, Kossor DC, Johnson PB, Levitt M.
    Toxicology; 1991 Apr 08; 67(2):143-54. PubMed ID: 2031249
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of spironolactone by adrenocortical and hepatic microsomes: relationship to cytochrome P-450 destruction.
    Sherry JH, O'Donnell JP, Flowers L, Lacagnin LB, Colby HD.
    J Pharmacol Exp Ther; 1986 Mar 08; 236(3):675-80. PubMed ID: 3950869
    [Abstract] [Full Text] [Related]

  • 4. Destruction of testicular cytochrome P-450 by 7 alpha-thiospironolactone is catalyzed by the 17 alpha-hydroxylase.
    Kossor DC, Kominami S, Takemori S, Colby HD.
    J Steroid Biochem Mol Biol; 1992 May 08; 42(3-4):421-4. PubMed ID: 1606053
    [Abstract] [Full Text] [Related]

  • 5. Spironolactone inhibition of cortisol production by guinea pig adrenocortical cells.
    Rourke KA, Colby HD.
    Horm Metab Res; 1990 Nov 08; 22(11):573-5. PubMed ID: 2177032
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of action of spironolactone on cortisol production by guinea pig adrenocortical cells.
    Rourke KA, Bergstrom JM, Larson IW, Colby HD.
    Mol Cell Endocrinol; 1991 Oct 08; 81(1-3):127-34. PubMed ID: 1797582
    [Abstract] [Full Text] [Related]

  • 7. Adrenal mitochondrial metabolism of spironolactone. Absence of metabolic activation.
    Flowers NL, Sherry JH, O'Donnell JP, Colby HD.
    Biochem Pharmacol; 1988 Apr 15; 37(8):1591-5. PubMed ID: 3358788
    [Abstract] [Full Text] [Related]

  • 8. Dose-dependent actions of spironolactone on the inner and outer zones of the guinea pig adrenal cortex.
    Kossor DC, Colby HD.
    Pharmacology; 1992 Apr 15; 45(1):27-33. PubMed ID: 1508965
    [Abstract] [Full Text] [Related]

  • 9. Examination of differences between benzo[a]pyrene and steroid hydroxylases in guinea pig adrenal microsomes.
    Mochizuki H, Kominami S, Takemori S.
    Biochim Biophys Acta; 1988 Jan 12; 964(1):83-9. PubMed ID: 3334876
    [Abstract] [Full Text] [Related]

  • 10. Studies on cytochrome P-450 (P-450 17 alpha,lyase) from guinea pig adrenal microsomes. Dual function of a single enzyme and effect of cytochrome b5.
    Shinzawa K, Kominami S, Takemori S.
    Biochim Biophys Acta; 1985 Jan 09; 833(1):151-60. PubMed ID: 3871334
    [Abstract] [Full Text] [Related]

  • 11. Regional differences in adrenal activation of spironolactone: relationship to steroid 17 alpha-hydroxylase activity.
    Sherry JH, Johnson PB, Levitt M, Bergstrom J, Colby HD.
    Drug Metab Dispos; 1989 Jan 09; 17(6):709-10. PubMed ID: 2575513
    [No Abstract] [Full Text] [Related]

  • 12. Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes.
    LaCagnin LB, Lutsie P, Colby HD.
    Biochem Pharmacol; 1987 Oct 15; 36(20):3439-44. PubMed ID: 3675606
    [Abstract] [Full Text] [Related]

  • 13. Stimulation of microsomal spironolactone metabolism by reduced glutathione.
    Colby HD, LaCagnin LB, Los LE.
    Pharmacology; 1996 Jan 15; 52(1):30-4. PubMed ID: 8966200
    [Abstract] [Full Text] [Related]

  • 14. The interference of polychlorinated biphenyls (Aroclor 1254) with membrane regulation of the activities of cytochromes P-450C21 and P-450(17) alpha,lyase in guinea-pig adrenal microsomes.
    Goldman D, Yawetz A.
    J Steroid Biochem Mol Biol; 1992 Mar 15; 42(1):37-47. PubMed ID: 1558819
    [Abstract] [Full Text] [Related]

  • 15. Mechanisms responsible for the thermal sensitivity of adrenal microsomal monooxygenases.
    Colby HD, Johnson PB, Pope MR.
    Drug Metab Dispos; 1991 Mar 15; 19(3):679-82. PubMed ID: 1680636
    [Abstract] [Full Text] [Related]

  • 16. Selective inactivation by 21-chlorinated steroids of rabbit liver and adrenal microsomal cytochromes P-450 involved in progesterone hydroxylation.
    Halpert J, Jaw JY, Balfour C, Mash EA, Johnson EF.
    Arch Biochem Biophys; 1988 Aug 01; 264(2):462-71. PubMed ID: 3261153
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of action of spironolactone on adrenocortical function in guinea pigs.
    Greiner JW, Kramer RE, Jarrell J, Colby HD.
    J Pharmacol Exp Ther; 1976 Sep 01; 198(3):709-15. PubMed ID: 978470
    [Abstract] [Full Text] [Related]

  • 18. The role of cytochrome b5 in adrenal microsomal steroidogenesis.
    Kominami S, Ogawa N, Morimune R, De-Ying H, Takemori S.
    J Steroid Biochem Mol Biol; 1992 Mar 01; 42(1):57-64. PubMed ID: 1558820
    [Abstract] [Full Text] [Related]

  • 19. Studies on the destruction of adrenal and testicular cytochrome P-450 by spironolactone. Requirement for the 7alpha-thio group and evidence for the loss of the heme and apoproteins of cytochrome P-450.
    Menard RH, Guenthner TM, Kon H, Gillette JR.
    J Biol Chem; 1979 Mar 10; 254(5):1726-33. PubMed ID: 762169
    [No Abstract] [Full Text] [Related]

  • 20. Relation of canrenone to the actions of spironolactone on adrenal cytochrome P-450 dependent enzymes.
    Greiner JW, Rumbaugh RC, Kramer RE, Colby HD.
    Endocrinology; 1978 Oct 10; 103(4):1313-20. PubMed ID: 311283
    [No Abstract] [Full Text] [Related]

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