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115 related items for PubMed ID: 18776555

  • 1. Nucleoside phosphonic acids in thymidine phosphorylase inhibition: structure-activity relationship.
    Panova N, Kosiová I, Petrová M, Vanĕk V, Liboska R, Kovacková S, Kocalka P, Králíková S, Tocík Z, Páv O, Paces O, Rejman D, Rosenberg I.
    Nucleic Acids Symp Ser (Oxf); 2008; (52):665-6. PubMed ID: 18776555
    [Abstract] [Full Text] [Related]

  • 2. Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
    Kocalka P, Rejman D, Vanek V, Rinnová M, Tomecková I, Králíková S, Petrová M, Páv O, Pohl R, Budesínský M, Liboska R, Tocík Z, Panova N, Votruba I, Rosenberg I.
    Bioorg Med Chem Lett; 2010 Feb 01; 20(3):862-5. PubMed ID: 20053558
    [Abstract] [Full Text] [Related]

  • 3. Syntheses of N3-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylase.
    Pomeisl K, Holý A, Votruba I, Pohl R.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1364-7. PubMed ID: 18221873
    [Abstract] [Full Text] [Related]

  • 4. Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
    Toms AV, Wang W, Li Y, Ganem B, Ealick SE.
    Acta Crystallogr D Biol Crystallogr; 2005 Nov 15; 61(Pt 11):1449-58. PubMed ID: 16239721
    [Abstract] [Full Text] [Related]

  • 5. Fluorophosphonylated nucleoside derivatives as new series of thymidine phosphorylase multisubstrate inhibitors.
    Diab SA, De Schutter C, Muzard M, Plantier-Royon R, Pfund E, Lequeux T.
    J Med Chem; 2012 Mar 22; 55(6):2758-68. PubMed ID: 22372816
    [Abstract] [Full Text] [Related]

  • 6. Pyrimidine acyclic nucleoside phosphonates and phosphorylated analogs. Part 2. Syntheses and investigation of their inhibitory effects towards human thymidine phosphorylase.
    Pomeisl K, Holý A, Votruba I.
    Nucleic Acids Symp Ser (Oxf); 2008 Mar 22; (52):657-8. PubMed ID: 18776551
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.
    Košiová I, Šimák O, Panova N, Buděšínský M, Petrová M, Rejman D, Liboska R, Páv O, Rosenberg I.
    Eur J Med Chem; 2014 Mar 03; 74():145-68. PubMed ID: 24462848
    [Abstract] [Full Text] [Related]

  • 8. Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma.
    Pomeisl K, Votruba I, Holý A, Pohl R.
    Nucleosides Nucleotides Nucleic Acids; 2007 Mar 03; 26(8-9):1025-8. PubMed ID: 18058530
    [Abstract] [Full Text] [Related]

  • 9. Syntheses of 1-[2-(Phosphonomethoxy)Alkyl] thymine monophosphates and an evaluation of their inhibitory activity toward human thymidine phosphorylase.
    Pomeisl K, Horská K, Pohl R, Blažek J, Krečmerová M.
    Nucleosides Nucleotides Nucleic Acids; 2012 Mar 03; 31(3):159-71. PubMed ID: 22356232
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition states.
    Dayde B, Benzaria S, Pierra C, Gosselin G, Surleraux D, Volle JN, Pirat JL, Virieux D.
    Org Biomol Chem; 2012 May 07; 10(17):3448-54. PubMed ID: 22434259
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of thymidine phosphorylase (PD-ECGF) from SD-lymphoma by phosphonomethoxyalkyl thymines.
    Votruba I, Pomeisl K, Tloust'ová E, Holý A, Otová B.
    Biochem Pharmacol; 2005 May 15; 69(10):1517-21. PubMed ID: 15857616
    [Abstract] [Full Text] [Related]

  • 12. Structure-activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase.
    Rajabi M, Mansell D, Freeman S, Bryce RA.
    Eur J Med Chem; 2011 Apr 15; 46(4):1165-71. PubMed ID: 21324566
    [Abstract] [Full Text] [Related]

  • 13. 5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis.
    Liekens S, Bronckaers A, Hernández AI, Priego EM, Casanova E, Camarasa MJ, Pérez-Pérez MJ, Balzarini J.
    Mol Pharmacol; 2006 Aug 15; 70(2):501-9. PubMed ID: 16675660
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase.
    Yano S, Kazuno H, Sato T, Suzuki N, Emura T, Wierzba K, Yamashita J, Tada Y, Yamada Y, Fukushima M, Asao T.
    Bioorg Med Chem; 2004 Jul 01; 12(13):3443-50. PubMed ID: 15186830
    [Abstract] [Full Text] [Related]

  • 15. 8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase.
    Mařák D, Otmar M, Votruba I, Dračínský M, Krečmerová M.
    Bioorg Med Chem Lett; 2011 Jan 15; 21(2):652-4. PubMed ID: 21195612
    [Abstract] [Full Text] [Related]

  • 16. 5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase.
    Casanova E, Hernandez AI, Priego EM, Liekens S, Camarasa MJ, Balzarini J, Pérez-Pérez MJ.
    J Med Chem; 2006 Sep 07; 49(18):5562-70. PubMed ID: 16942029
    [Abstract] [Full Text] [Related]

  • 17. Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors.
    Khan KM, Ambreen N, Hussain S, Perveen S, Choudhary MI.
    Bioorg Med Chem; 2009 Apr 15; 17(8):2983-8. PubMed ID: 19329330
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase.
    Allan AL, Gladstone PL, Price ML, Hopkins SA, Juarez JC, Doñate F, Ternansky RJ, Shaw DE, Ganem B, Li Y, Wang W, Ealick S.
    J Med Chem; 2006 Dec 28; 49(26):7807-15. PubMed ID: 17181163
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
    Nencka R, Votruba I, Hrebabecký H, Tloust'ová E, Horská K, Masojídková M, Holý A.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1335-7. PubMed ID: 16337119
    [Abstract] [Full Text] [Related]

  • 20. Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.
    Glavas-Obrovac L, Suver M, Hikishima S, Hashimoto M, Yokomatsu T, Magnowska L, Bzowska A.
    Chem Biol Drug Des; 2010 Apr 01; 75(4):392-9. PubMed ID: 20102369
    [Abstract] [Full Text] [Related]

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