These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

261 related items for PubMed ID: 18791060

  • 1. Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory and neuropathic pain.
    Munro G, Lopez-Garcia JA, Rivera-Arconada I, Erichsen HK, Nielsen EØ, Larsen JS, Ahring PK, Mirza NR.
    J Pharmacol Exp Ther; 2008 Dec; 327(3):969-81. PubMed ID: 18791060
    [Abstract] [Full Text] [Related]

  • 2. NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile], a unique subtype-selective GABAA receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy.
    Mirza NR, Larsen JS, Mathiasen C, Jacobsen TA, Munro G, Erichsen HK, Nielsen AN, Troelsen KB, Nielsen EØ, Ahring PK.
    J Pharmacol Exp Ther; 2008 Dec; 327(3):954-68. PubMed ID: 18791063
    [Abstract] [Full Text] [Related]

  • 3. GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric modulator NS16085.
    de Lucas AG, Ahring PK, Larsen JS, Rivera-Arconada I, Lopez-Garcia JA, Mirza NR, Munro G.
    Biochem Pharmacol; 2015 Feb 01; 93(3):370-9. PubMed ID: 25542996
    [Abstract] [Full Text] [Related]

  • 4. A question of balance--positive versus negative allosteric modulation of GABA(A) receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain.
    Munro G, Erichsen HK, Rae MG, Mirza NR.
    Neuropharmacology; 2011 Feb 01; 61(1-2):121-32. PubMed ID: 21439986
    [Abstract] [Full Text] [Related]

  • 5. Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain.
    Rode F, Jensen DG, Blackburn-Munro G, Bjerrum OJ.
    Eur J Pharmacol; 2005 Jun 01; 516(2):131-8. PubMed ID: 15936014
    [Abstract] [Full Text] [Related]

  • 6. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
    Giusti P, Ducić I, Puia G, Arban R, Walser A, Guidotti A, Costa E.
    J Pharmacol Exp Ther; 1993 Aug 01; 266(2):1018-28. PubMed ID: 8394902
    [Abstract] [Full Text] [Related]

  • 7. Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats.
    Hansen RR, Erichsen HK, Brown DT, Mirza NR, Munro G.
    Neuropharmacology; 2012 Dec 01; 63(8):1360-7. PubMed ID: 22985969
    [Abstract] [Full Text] [Related]

  • 8. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS.
    J Pharmacol Exp Ther; 2006 Dec 01; 319(3):1244-52. PubMed ID: 16971504
    [Abstract] [Full Text] [Related]

  • 9. Developing analgesics by enhancing spinal inhibition after injury: GABAA receptor subtypes as novel targets.
    Munro G, Ahring PK, Mirza NR.
    Trends Pharmacol Sci; 2009 Sep 01; 30(9):453-9. PubMed ID: 19729210
    [Abstract] [Full Text] [Related]

  • 10. Comparative cue generalization profiles of L-838, 417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, zopiclone, and various benzodiazepines in chlordiazepoxide and zolpidem drug discrimination.
    Mirza NR, Rodgers RJ, Mathiasen LS.
    J Pharmacol Exp Ther; 2006 Mar 01; 316(3):1291-9. PubMed ID: 16339395
    [Abstract] [Full Text] [Related]

  • 11. Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABAA receptors.
    Söderhielm PC, Balle T, Bak-Nyhus S, Zhang M, Hansen KM, Ahring PK, Jensen AA.
    Biochem Pharmacol; 2018 Dec 01; 158():339-358. PubMed ID: 30121248
    [Abstract] [Full Text] [Related]

  • 12. Gaboxadol -- a different hypnotic profile with no tolerance to sleep EEG and sedative effects after repeated daily dosing.
    Ebert B, Anderson NJ, Cremers TI, Rasmussen S, Vogel V, Fahey JM, Sánchez C.
    Pharmacol Biochem Behav; 2008 Jul 01; 90(1):113-22. PubMed ID: 18304623
    [Abstract] [Full Text] [Related]

  • 13. Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat.
    Auta J, Giusti P, Guidotti A, Costa E.
    J Pharmacol Exp Ther; 1994 Sep 01; 270(3):1262-9. PubMed ID: 7932179
    [Abstract] [Full Text] [Related]

  • 14. Pharmacological properties of GABAA receptors containing gamma1 subunits.
    Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S.
    Mol Pharmacol; 2006 Feb 01; 69(2):640-9. PubMed ID: 16272224
    [Abstract] [Full Text] [Related]

  • 15. Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys.
    Platt DM, Rowlett JK, Spealman RD, Cook J, Ma C.
    Psychopharmacology (Berl); 2002 Nov 01; 164(2):151-9. PubMed ID: 12404077
    [Abstract] [Full Text] [Related]

  • 16. Comparative effects of nonselective and subtype-selective gamma-aminobutyric acidA receptor positive modulators in the rat-conditioned emotional response test.
    Mathiasen LS, Rodgers RJ, Mirza NR.
    Behav Pharmacol; 2007 May 01; 18(3):191-203. PubMed ID: 17426483
    [Abstract] [Full Text] [Related]

  • 17. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function.
    Hofmann M, Kordás KS, Gravius A, Bölcskei K, Parsons CG, Dekundy A, Danysz W, Dézsi L, Wittko-Schneider IM, Sághy K, Gyertyán I, Horváth C.
    Behav Pharmacol; 2012 Dec 01; 23(8):790-801. PubMed ID: 23075708
    [Abstract] [Full Text] [Related]

  • 18. Reduced GABA neurotransmission underlies hyperalgesia induced by repeated forced swimming stress.
    Suarez-Roca H, Leal L, Silva JA, Pinerua-Shuhaibar L, Quintero L.
    Behav Brain Res; 2008 May 16; 189(1):159-69. PubMed ID: 18255166
    [Abstract] [Full Text] [Related]

  • 19. The role of GABA(A) receptor subtypes as analgesic targets.
    Mirza NR, Munro G.
    Drug News Perspect; 2010 May 16; 23(6):351-60. PubMed ID: 20697602
    [Abstract] [Full Text] [Related]

  • 20. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem.
    Vinkers CH, Olivier B, Hanania T, Min W, Schreiber R, Hopkins SC, Campbell U, Paterson N.
    Eur J Pharmacol; 2011 Oct 01; 668(1-2):190-3. PubMed ID: 21762686
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 14.