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Journal Abstract Search

172 related items for PubMed ID: 18795946

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  • 3. The kinetic mechanism of S. pneumoniae DNA ligase and inhibition by adenosine-based antibacterial compounds.
    Jahić H, Liu CF, Thresher J, Livchak S, Wang H, Ehmann DE.
    Biochem Pharmacol; 2012 Sep 01; 84(5):654-60. PubMed ID: 22743594
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  • 4. Identification through structure-based methods of a bacterial NAD(+)-dependent DNA ligase inhibitor that avoids known resistance mutations.
    Murphy-Benenato K, Wang H, McGuire HM, Davis HE, Gao N, Prince DB, Jahic H, Stokes SS, Boriack-Sjodin PA.
    Bioorg Med Chem Lett; 2014 Jan 01; 24(1):360-6. PubMed ID: 24287382
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  • 5. Discovery of bacterial NAD+-dependent DNA ligase inhibitors: optimization of antibacterial activity.
    Stokes SS, Huynh H, Gowravaram M, Albert R, Cavero-Tomas M, Chen B, Harang J, Loch JT, Lu M, Mullen GB, Zhao S, Liu CF, Mills SD.
    Bioorg Med Chem Lett; 2011 Aug 01; 21(15):4556-60. PubMed ID: 21719282
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  • 6. Novel bacterial NAD+-dependent DNA ligase inhibitors with broad-spectrum activity and antibacterial efficacy in vivo.
    Mills SD, Eakin AE, Buurman ET, Newman JV, Gao N, Huynh H, Johnson KD, Lahiri S, Shapiro AB, Walkup GK, Yang W, Stokes SS.
    Antimicrob Agents Chemother; 2011 Mar 01; 55(3):1088-96. PubMed ID: 21189350
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  • 7. Streptococcus pneumononiae gyrase ATPase: development and validation of an assay for inhibitor discovery and characterization.
    Miller JR, Herberg JT, Tomilo M, McCroskey MC, Feilmeier BJ.
    Anal Biochem; 2007 Jun 01; 365(1):132-43. PubMed ID: 17395144
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  • 8. A high-throughput assay for the adenylation reaction of bacterial DNA ligase.
    Miesel L, Kravec C, Xin AT, McMonagle P, Ma S, Pichardo J, Feld B, Barrabee E, Palermo R.
    Anal Biochem; 2007 Jul 01; 366(1):9-17. PubMed ID: 17493575
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  • 9. Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination.
    Chen XC, Hentz NG, Hubbard F, Meier TI, Sittampalam S, Zhao G.
    Anal Biochem; 2002 Oct 15; 309(2):232-40. PubMed ID: 12413456
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  • 10. Enzymes involved in DNA ligation and end-healing in the radioresistant bacterium Deinococcus radiodurans.
    Blasius M, Buob R, Shevelev IV, Hubscher U.
    BMC Mol Biol; 2007 Aug 16; 8():69. PubMed ID: 17705817
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  • 11. Cloning and functional characterization of an NAD(+)-dependent DNA ligase from Staphylococcus aureus.
    Kaczmarek FS, Zaniewski RP, Gootz TD, Danley DE, Mansour MN, Griffor M, Kamath AV, Cronan M, Mueller J, Sun D, Martin PK, Benton B, McDowell L, Biek D, Schmid MB.
    J Bacteriol; 2001 May 16; 183(10):3016-24. PubMed ID: 11325928
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  • 12. Characterization of mimivirus NAD+-dependent DNA ligase.
    Benarroch D, Shuman S.
    Virology; 2006 Sep 15; 353(1):133-43. PubMed ID: 16844179
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  • 13. A high-throughput fluorescence resonance energy transfer-based assay for DNA ligase.
    Shapiro AB, Eakin AE, Walkup GK, Rivin O.
    J Biomol Screen; 2011 Jun 15; 16(5):486-93. PubMed ID: 21398623
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  • 14. Evaluation of NAD(+) -dependent DNA ligase of mycobacteria as a potential target for antibiotics.
    Korycka-Machala M, Rychta E, Brzostek A, Sayer HR, Rumijowska-Galewicz A, Bowater RP, Dziadek J.
    Antimicrob Agents Chemother; 2007 Aug 15; 51(8):2888-97. PubMed ID: 17548501
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  • 15. Mycobacterium tuberculosis NAD+-dependent DNA ligase is selectively inhibited by glycosylamines compared with human DNA ligase I.
    Srivastava SK, Dube D, Tewari N, Dwivedi N, Tripathi RP, Ramachandran R.
    Nucleic Acids Res; 2005 Aug 15; 33(22):7090-101. PubMed ID: 16361267
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  • 16. Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part I: aminoalkoxypyrimidine carboxamides.
    Gu W, Wang T, Maltais F, Ledford B, Kennedy J, Wei Y, Gross CH, Parsons J, Duncan L, Arends SJ, Moody C, Perola E, Green J, Charifson PS.
    Bioorg Med Chem Lett; 2012 Jun 01; 22(11):3693-8. PubMed ID: 22560473
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  • 17. Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal.
    Gajiwala KS, Pinko C.
    Structure; 2004 Aug 01; 12(8):1449-59. PubMed ID: 15296738
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  • 18. Negishi cross-coupling enabled synthesis of novel NAD(+)-dependent DNA ligase inhibitors and SAR development.
    Murphy-Benenato KE, Gingipalli L, Boriack-Sjodin PA, Martinez-Botella G, Carcanague D, Eyermann CJ, Gowravaram M, Harang J, Hale MR, Ioannidis G, Jahic H, Johnstone M, Kutschke A, Laganas VA, Loch JT, Miller MD, Oguto H, Patel SJ.
    Bioorg Med Chem Lett; 2015 Nov 15; 25(22):5172-7. PubMed ID: 26463129
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  • 19. Discovery and Optimization of NAD+-Dependent DNA Ligase Inhibitors as Novel Antibacterial Compounds.
    Bi F, Ma R, Ma S.
    Curr Pharm Des; 2017 Nov 15; 23(14):2117-2130. PubMed ID: 27784238
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  • 20. Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I.
    Yadav N, Khanam T, Shukla A, Rai N, Hajela K, Ramachandran R.
    Org Biomol Chem; 2015 May 21; 13(19):5475-87. PubMed ID: 25875403
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