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127 related items for PubMed ID: 1880717

  • 1. Disposition of methylprednisolone and its sodium succinate prodrug in vivo and in perfused liver of rats: nonlinear and sequential first-pass elimination.
    Kong AN, Jusko WJ.
    J Pharm Sci; 1991 May; 80(5):409-15. PubMed ID: 1880717
    [Abstract] [Full Text] [Related]

  • 2. Bioavailability and nonlinear disposition of methylprednisolone and methylprednisone in the rat.
    Haughey DB, Jusko WJ.
    J Pharm Sci; 1992 Feb; 81(2):117-21. PubMed ID: 1545348
    [Abstract] [Full Text] [Related]

  • 3. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: plasma and tissue disposition.
    Zhang X, Mehvar R.
    J Pharm Sci; 2001 Dec; 90(12):2078-87. PubMed ID: 11745766
    [Abstract] [Full Text] [Related]

  • 4. Kinetics of hydrolysis of dextran-methylprednisolone succinate, a macromolecular prodrug of methylprednisolone, in rat blood and liver lysosomes.
    Mehvar R, Dann RO, Hoganson DA.
    J Control Release; 2000 Jul 31; 68(1):53-61. PubMed ID: 10884579
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics of methylprednisolone sodium succinate and methylprednisolone in patients undergoing cardiopulmonary bypass.
    Kong AN, Jungbluth GL, Pasko MT, Beam TR, Jusko WJ.
    Pharmacotherapy; 1990 Jul 31; 10(1):29-34. PubMed ID: 2179900
    [Abstract] [Full Text] [Related]

  • 6. A comparative population pharmacokinetic analysis for methylprednisolone following multiple dosing of two prodrugs in patients with acute asthma.
    Parker TJ, Daley-Yates PT, Wood SA.
    Br J Clin Pharmacol; 1997 Jun 31; 43(6):589-92. PubMed ID: 9205818
    [Abstract] [Full Text] [Related]

  • 7. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: local immunosuppressive effects in liver after systemic administration to rats.
    Chimalakonda AP, Mehvar R.
    Pharm Res; 2003 Feb 31; 20(2):198-204. PubMed ID: 12636157
    [Abstract] [Full Text] [Related]

  • 8. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: dose-dependent pharmacokinetics in rats.
    Zhang X, Mehvar R.
    Int J Pharm; 2001 Oct 23; 229(1-2):173-82. PubMed ID: 11604270
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics of methylprednisolone hemisuccinate and methylprednisolone in chronic liver disease.
    Ludwig EA, Kong AN, Camara DS, Jusko WJ.
    J Clin Pharmacol; 1993 Sep 23; 33(9):805-10. PubMed ID: 8227476
    [Abstract] [Full Text] [Related]

  • 10. Pilot study of the pharmacokinetics of methylprednisolone after single and multiple intravenous doses of methylprednisolone sodium succinate and methylprednisolone suleptanate to healthy volunteers.
    Ferry JJ, Della-Coletta AA, Weber DJ, VanderLugt JT.
    J Clin Pharmacol; 1994 Nov 23; 34(11):1109-15. PubMed ID: 7876403
    [Abstract] [Full Text] [Related]

  • 11. Pharmacokinetic and pharmacodynamic assessment of bioavailability for two prodrugs of methylprednisolone.
    Daley-Yates PT, Gregory AJ, Brooks CD.
    Br J Clin Pharmacol; 1997 Jun 23; 43(6):593-601. PubMed ID: 9205819
    [Abstract] [Full Text] [Related]

  • 12. Pharmacokinetics of methylprednisolone succinate, methylprednisolone, and lidocaine in the normal dog and during hemorrhagic shock.
    Toutain PL, Autefage A, Oukessou M, Alvinerie M.
    J Pharm Sci; 1987 Jul 23; 76(7):528-34. PubMed ID: 3312572
    [Abstract] [Full Text] [Related]

  • 13. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: immunosuppressive effects after in vivo administration to rats.
    Mehvar R, Hoganson DA.
    Pharm Res; 2000 Nov 23; 17(11):1402-7. PubMed ID: 11205734
    [Abstract] [Full Text] [Related]

  • 14. Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats.
    Konishi H, Sumi M, Shibata N, Takada K, Minouchi T, Yamaji A.
    J Pharm Pharmacol; 2004 Apr 23; 56(4):477-83. PubMed ID: 15099443
    [Abstract] [Full Text] [Related]

  • 15. Methylprednisolone pharmacokinetics after intravenous and oral administration.
    Al-Habet SM, Rogers HJ.
    Br J Clin Pharmacol; 1989 Mar 23; 27(3):285-90. PubMed ID: 2655680
    [Abstract] [Full Text] [Related]

  • 16. Plasma pharmacokinetics and tissue disposition of novel dextran-methylprednisolone conjugates with peptide linkers in rats.
    Penugonda S, Agarwal HK, Parang K, Mehvar R.
    J Pharm Sci; 2010 Mar 23; 99(3):1626-37. PubMed ID: 19780131
    [Abstract] [Full Text] [Related]

  • 17. Hepatic immunosuppressive effects of systemically administered novel dextran-methylprednisolone prodrugs with peptide linkers in rats.
    Shaik IH, Agarwal HK, Parang K, Mehvar R.
    J Pharm Sci; 2012 Oct 23; 101(10):4003-12. PubMed ID: 22829462
    [Abstract] [Full Text] [Related]

  • 18. Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.
    Barth J, Winkler J, Schumann R, Nagaraja NV, Madabushi R, Balbach S, Derendorf H, Möllmann H, Möllenhoff G.
    Int J Clin Pharmacol Ther; 2004 Sep 23; 42(9):504-11. PubMed ID: 15487809
    [Abstract] [Full Text] [Related]

  • 19. Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studies.
    Prueksaritanont T, Gorham LM, Ellis JD, Fernandez-Metzler C, Deluna P, Gehret JR, Strong KL, Hochman JH, Askew BC, Duggan ME, Gilbert JD, Lin JH, Vyas KP.
    Drug Metab Dispos; 1996 Nov 23; 24(11):1263-71. PubMed ID: 8937862
    [Abstract] [Full Text] [Related]

  • 20. Pharmacokinetics of methylprednisolone, methylprednisolone sodium succinate, and methylprednisolone acetate in dogs.
    Toutain PL, Koritz GD, Fayolle PM, Alvinerie M.
    J Pharm Sci; 1986 Mar 23; 75(3):251-5. PubMed ID: 3517294
    [Abstract] [Full Text] [Related]

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