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247 related items for PubMed ID: 18815274

  • 1. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
    Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER.
    Mol Biol Cell; 2008 Dec; 19(12):5226-37. PubMed ID: 18815274
    [Abstract] [Full Text] [Related]

  • 2. SV2 is the protein receptor for botulinum neurotoxin A.
    Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER.
    Science; 2006 Apr 28; 312(5773):592-6. PubMed ID: 16543415
    [Abstract] [Full Text] [Related]

  • 3. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep 28; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 4. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 28; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 5. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Mar 28; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 6. SV2 mediates entry of tetanus neurotoxin into central neurons.
    Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER.
    PLoS Pathog; 2010 Nov 24; 6(11):e1001207. PubMed ID: 21124874
    [Abstract] [Full Text] [Related]

  • 7. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 8. SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family.
    Janz R, Südhof TC.
    Neuroscience; 1999 Jun 23; 94(4):1279-90. PubMed ID: 10625067
    [Abstract] [Full Text] [Related]

  • 9. Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors.
    Azzaz F, Hilaire D, Fantini J.
    Chem Biol Interact; 2023 Mar 01; 373():110384. PubMed ID: 36754227
    [Abstract] [Full Text] [Related]

  • 10. Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells.
    Dong M, Richards DA, Goodnough MC, Tepp WH, Johnson EA, Chapman ER.
    J Cell Biol; 2003 Sep 29; 162(7):1293-303. PubMed ID: 14504267
    [Abstract] [Full Text] [Related]

  • 11. Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons.
    Dong M, Tepp WH, Liu H, Johnson EA, Chapman ER.
    J Cell Biol; 2007 Dec 31; 179(7):1511-22. PubMed ID: 18158333
    [Abstract] [Full Text] [Related]

  • 12. SV2A and SV2C contain a unique synaptotagmin-binding site.
    Schivell AE, Mochida S, Kensel-Hammes P, Custer KL, Bajjalieh SM.
    Mol Cell Neurosci; 2005 May 31; 29(1):56-64. PubMed ID: 15866046
    [Abstract] [Full Text] [Related]

  • 13. Novel ganglioside-mediated entry of botulinum neurotoxin serotype D into neurons.
    Kroken AR, Karalewitz AP, Fu Z, Kim JJ, Barbieri JT.
    J Biol Chem; 2011 Jul 29; 286(30):26828-37. PubMed ID: 21632541
    [Abstract] [Full Text] [Related]

  • 14. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system.
    Blum FC, Chen C, Kroken AR, Barbieri JT.
    Infect Immun; 2012 May 29; 80(5):1662-9. PubMed ID: 22392932
    [Abstract] [Full Text] [Related]

  • 15. Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
    Liu Z, Lee PG, Krez N, Lam KH, Liu H, Przykopanski A, Chen P, Yao G, Zhang S, Tremblay JM, Perry K, Shoemaker CB, Rummel A, Dong M, Jin R.
    Nat Commun; 2023 Apr 24; 14(1):2338. PubMed ID: 37095076
    [Abstract] [Full Text] [Related]

  • 16. Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.
    Venkatesan K, Alix P, Marquet A, Doupagne M, Niespodziany I, Rogister B, Seutin V.
    J Neurosci Res; 2012 Dec 24; 90(12):2317-27. PubMed ID: 22847229
    [Abstract] [Full Text] [Related]

  • 17. SV2 regulates neurotransmitter release via multiple mechanisms.
    Nowack A, Yao J, Custer KL, Bajjalieh SM.
    Am J Physiol Cell Physiol; 2010 Nov 24; 299(5):C960-7. PubMed ID: 20702688
    [Abstract] [Full Text] [Related]

  • 18. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin.
    Weisemann J, Stern D, Mahrhold S, Dorner BG, Rummel A.
    Toxins (Basel); 2016 May 17; 8(5):. PubMed ID: 27196927
    [Abstract] [Full Text] [Related]

  • 19. Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
    Rummel A, Karnath T, Henke T, Bigalke H, Binz T.
    J Biol Chem; 2004 Jul 16; 279(29):30865-70. PubMed ID: 15123599
    [Abstract] [Full Text] [Related]

  • 20. Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
    Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.
    J Biol Chem; 2012 Nov 23; 287(48):40806-16. PubMed ID: 23027864
    [Abstract] [Full Text] [Related]

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