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Journal Abstract Search

401 related items for PubMed ID: 18822345

  • 1. 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds.
    Blum A, Favia AD, Maser E.
    Mol Cell Endocrinol; 2009 Mar 25; 301(1-2):132-6. PubMed ID: 18822345
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  • 3. Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
    Hult M, Shafqat N, Elleby B, Mitschke D, Svensson S, Forsgren M, Barf T, Vallgårda J, Abrahmsen L, Oppermann U.
    Mol Cell Endocrinol; 2006 Mar 27; 248(1-2):26-33. PubMed ID: 16431016
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  • 4. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X, Vicker N, Trusselle M, Halem H, Culler MD, Potter BV.
    Mol Cell Endocrinol; 2009 Mar 25; 301(1-2):169-73. PubMed ID: 18775471
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  • 5. Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.
    Lagos CF, Vecchiola A, Allende F, Fuentes CA, Tichauer JE, Valdivia C, Solari S, Campino C, Tapia-Castillo A, Baudrand R, Villarroel P, Cifuentes M, Owen GI, Carvajal CA, Fardella CE.
    Mol Cell Endocrinol; 2014 Mar 25; 384(1-2):71-82. PubMed ID: 24447464
    [Abstract] [Full Text] [Related]

  • 6. 17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes.
    Tagawa N, Yuda R, Kubota S, Wakabayashi M, Yamaguchi Y, Kiyonaga D, Mori N, Minamitani E, Masuzaki H, Kobayashi Y.
    J Endocrinol; 2009 Jul 25; 202(1):131-9. PubMed ID: 19380458
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  • 7. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors for metabolic syndrome.
    Schnackenberg CG.
    Curr Opin Investig Drugs; 2008 Mar 25; 9(3):295-300. PubMed ID: 18311666
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  • 8. Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy.
    Wang M.
    Handb Exp Pharmacol; 2011 Mar 25; (203):127-46. PubMed ID: 21484570
    [Abstract] [Full Text] [Related]

  • 9. Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase 1 inhibitors.
    Cho YS, Kim CH, Cheon HG.
    Anal Biochem; 2009 Sep 15; 392(2):110-6. PubMed ID: 19497289
    [Abstract] [Full Text] [Related]

  • 10. Human adipose tissue under in vitro inhibition of 11beta-hydroxysteroid dehydrogenase type 1: differentiation and metabolism changes.
    Bader T, Zoumakis E, Friedberg M, Hiroi N, Chrousos GP, Hochberg Z.
    Horm Metab Res; 2002 Sep 15; 34(11-12):752-7. PubMed ID: 12660894
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  • 12. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents.
    Boyle CD, Kowalski TJ.
    Expert Opin Ther Pat; 2009 Jun 15; 19(6):801-25. PubMed ID: 19456274
    [Abstract] [Full Text] [Related]

  • 13. Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X, Vicker N, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV.
    Mol Cell Endocrinol; 2006 Mar 27; 248(1-2):214-7. PubMed ID: 16325333
    [Abstract] [Full Text] [Related]

  • 14. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Roche D, Carniato D, Leriche C, Lepifre F, Christmann-Franck S, Graedler U, Charon C, Bozec S, Doare L, Schmidlin F, Lecomte M, Valeur E.
    Bioorg Med Chem Lett; 2009 May 15; 19(10):2674-8. PubMed ID: 19395260
    [Abstract] [Full Text] [Related]

  • 15. Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Tu H, Powers JP, Liu J, Ursu S, Sudom A, Yan X, Xu H, Meininger D, Degraffenreid M, He X, Jaen JC, Sun D, Labelle M, Yamamoto H, Shan B, Walker NP, Wang Z.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8922-31. PubMed ID: 18789704
    [Abstract] [Full Text] [Related]

  • 16. Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species.
    Arampatzis S, Kadereit B, Schuster D, Balazs Z, Schweizer RA, Frey FJ, Langer T, Odermatt A.
    J Mol Endocrinol; 2005 Aug 01; 35(1):89-101. PubMed ID: 16087724
    [Abstract] [Full Text] [Related]

  • 17. 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders?
    Anagnostis P, Katsiki N, Adamidou F, Athyros VG, Karagiannis A, Kita M, Mikhailidis DP.
    Metabolism; 2013 Jan 01; 62(1):21-33. PubMed ID: 22652056
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  • 18. Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.
    Xiang J, Wan ZK, Li HQ, Ipek M, Binnun E, Nunez J, Chen L, McKew JC, Mansour TS, Xu X, Suri V, Tam M, Xing Y, Li X, Hahm S, Tobin J, Saiah E.
    J Med Chem; 2008 Jul 24; 51(14):4068-71. PubMed ID: 18578516
    [Abstract] [Full Text] [Related]

  • 19. Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.
    Stimson RH, Walker BR.
    Minerva Endocrinol; 2007 Sep 24; 32(3):141-59. PubMed ID: 17912154
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
    Dhanesha N, Joharapurkar A, Shah G, Kshirsagar S, Dhote V, Sharma A, Jain M.
    Clin Exp Pharmacol Physiol; 2012 Jan 24; 39(1):69-77. PubMed ID: 22060140
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