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Journal Abstract Search

325 related items for PubMed ID: 18826203

  • 21. Synthesis, hydrolysis and anti-EBV activity of a series of 3'-modified cycloSal-BVDUMP pronucleotides.
    Meier C, Lomp A, Meerbach A, Wutzler P.
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):307-14. PubMed ID: 11563042
    [Abstract] [Full Text] [Related]

  • 22. Phosphorodiamides as prodrugs for antiviral nucleosides.
    Shipitsyn AV, Zakirova NF, Belanov EF, Pronyaeva TR, Fedyuk NV, Kukhanova MK, Pokrovsky AG.
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):963-6. PubMed ID: 14565322
    [Abstract] [Full Text] [Related]

  • 23. The DiPPro approach: synthesis, hydrolysis, and antiviral activity of lipophilic d4T diphosphate prodrugs.
    Schulz T, Balzarini J, Meier C.
    ChemMedChem; 2014 Apr; 9(4):762-75. PubMed ID: 24616176
    [Abstract] [Full Text] [Related]

  • 24. Stereoselective synthesis and antiviral activity of methyl-substituted cycloSal-pronucleotides.
    Rios Morales EH, Balzarini J, Meier C.
    J Med Chem; 2012 Aug 23; 55(16):7245-52. PubMed ID: 22827702
    [Abstract] [Full Text] [Related]

  • 25. Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity.
    Santos C, Morais J, Gouveia L, de Clercq E, Pannecouque C, Nielsen CU, Steffansen B, Moreira R, Gomes P.
    ChemMedChem; 2008 Jun 23; 3(6):970-8. PubMed ID: 18389514
    [Abstract] [Full Text] [Related]

  • 26. Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Saboulard D, Naesens L, Cahard D, Salgado A, Pathirana R, Velazquez S, McGuigan C, De Clercq E, Balzarini J.
    Mol Pharmacol; 1999 Oct 23; 56(4):693-704. PubMed ID: 10496951
    [Abstract] [Full Text] [Related]

  • 27. [Design, synthesis and anti-HBV activity of L-amino acid ester prodrugs of acyclic nucleoside phosphonates].
    Fu XZ, Jiang SH, Yang YS, Ji RY.
    Yao Xue Xue Bao; 2008 May 23; 43(5):495-503. PubMed ID: 18717337
    [Abstract] [Full Text] [Related]

  • 28. New insights regarding the potential of the pronucleotide approach in antiviral chemotherapy.
    Gosselin G, Girardet JL, Périgaud C, Benzaria S, Lefebvre I, Schlienger N, Pompon A, Imbach JL.
    Acta Biochim Pol; 1996 May 23; 43(1):196-208. PubMed ID: 8790724
    [Abstract] [Full Text] [Related]

  • 29. Intracellular trapping of cycloSal-pronucleotides by enzymatic cleavage.
    Jessen HJ, Tonn V, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2007 May 23; 26(6-7):827-30. PubMed ID: 18066908
    [Abstract] [Full Text] [Related]

  • 30. Synthesis of stavudine amino acid ester prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS.
    Sriram D, Yogeeswari P, Srichakravarthy N, Bal TR.
    Bioorg Med Chem Lett; 2004 Mar 08; 14(5):1085-7. PubMed ID: 14980640
    [Abstract] [Full Text] [Related]

  • 31. Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity.
    Meier C, Muus U, Renze J, Naesens L, De Clercq E, Balzarini J.
    Antivir Chem Chemother; 2002 Mar 08; 13(2):101-14. PubMed ID: 12238528
    [Abstract] [Full Text] [Related]

  • 32. cycloSal-pronucleotides design of chemical trojan horses.
    Meier C.
    Mini Rev Med Chem; 2002 Jun 08; 2(3):219-34. PubMed ID: 12370064
    [Abstract] [Full Text] [Related]

  • 33. Synthesis and anti-HIV activity of steroidal prodrugs of 3'-azido-3'-deoxythymidine (AZT).
    Balagopala MI, Ollapally AP, Lee HJ.
    Cell Mol Biol (Noisy-le-grand); 1995 Jun 08; 41 Suppl 1():S1-7. PubMed ID: 8574137
    [Abstract] [Full Text] [Related]

  • 34. Second generation of cycloSal-pronucleotides with esterase-cleavable sites: the "lock-in"-concept.
    Meier C, Ruppel MF, Vukadinović D, Balzarini J.
    Nucleosides Nucleotides Nucleic Acids; 2004 Jun 08; 23(1-2):89-115. PubMed ID: 15043139
    [Abstract] [Full Text] [Related]

  • 35. Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.
    Song X, Vig BS, Lorenzi PL, Drach JC, Townsend LB, Amidon GL.
    J Med Chem; 2005 Feb 24; 48(4):1274-7. PubMed ID: 15715497
    [Abstract] [Full Text] [Related]

  • 36. Studies on enzyme-cleavable dialkoxymethyl-cyclosaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates.
    Gisch N, Balzarini J, Meier C.
    J Med Chem; 2008 Nov 13; 51(21):6752-60. PubMed ID: 18834186
    [Abstract] [Full Text] [Related]

  • 37. cycloSal-PMEA and cycloAmb-PMEA: potentially new phosphonate prodrugs based on the cycloSal-pronucleotide approach.
    Meier C, Görbig U, Müller C, Balzarini J.
    J Med Chem; 2005 Dec 15; 48(25):8079-86. PubMed ID: 16335932
    [Abstract] [Full Text] [Related]

  • 38. Synthesis and in vitro evaluation of S-acyl-3-thiopropyl prodrugs of Foscarnet.
    Gagnard V, Leydet A, Morère A, Montero JL, Lefèbvre I, Gosselin G, Pannecouque C, De Clercq E.
    Bioorg Med Chem; 2004 Mar 15; 12(6):1393-402. PubMed ID: 15018912
    [Abstract] [Full Text] [Related]

  • 39. Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides.
    Shirokova EA, Jasko MV, Khandazhinskaya AL, Ivanov AV, Yanvarev DV, Skoblov YS, Mitkevich VA, Bocharov EV, Pronyaeva TR, Fedyuk NV, Kukhanova MK, Pokrovsky AG.
    J Med Chem; 2004 Jul 01; 47(14):3606-14. PubMed ID: 15214788
    [Abstract] [Full Text] [Related]

  • 40. Structure-activity relationships for dipeptide prodrugs of acyclovir: implications for prodrug design.
    Santos CR, Capela R, Pereira CS, Valente E, Gouveia L, Pannecouque C, De Clercq E, Moreira R, Gomes P.
    Eur J Med Chem; 2009 Jun 01; 44(6):2339-46. PubMed ID: 18848738
    [Abstract] [Full Text] [Related]

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