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910 related items for PubMed ID: 18829553

  • 1. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo.
    Vogler M, Walczak H, Stadel D, Haas TL, Genze F, Jovanovic M, Gschwend JE, Simmet T, Debatin KM, Fulda S.
    Cancer Res; 2008 Oct 01; 68(19):7956-65. PubMed ID: 18829553
    [Abstract] [Full Text] [Related]

  • 2. Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.
    Vogler M, Walczak H, Stadel D, Haas TL, Genze F, Jovanovic M, Bhanot U, Hasel C, Möller P, Gschwend JE, Simmet T, Debatin KM, Fulda S.
    Cancer Res; 2009 Mar 15; 69(6):2425-34. PubMed ID: 19258513
    [Abstract] [Full Text] [Related]

  • 3. Regulation of TRAIL-induced apoptosis by XIAP in pancreatic carcinoma cells.
    Vogler M, Dürr K, Jovanovic M, Debatin KM, Fulda S.
    Oncogene; 2007 Jan 11; 26(2):248-57. PubMed ID: 16832350
    [Abstract] [Full Text] [Related]

  • 4. A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
    Ndozangue-Touriguine O, Sebbagh M, Mérino D, Micheau O, Bertoglio J, Bréard J.
    Oncogene; 2008 Oct 09; 27(46):6012-22. PubMed ID: 18560353
    [Abstract] [Full Text] [Related]

  • 5. Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma.
    Opel D, Naumann I, Schneider M, Bertele D, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 May 15; 17(10):3233-47. PubMed ID: 21355080
    [Abstract] [Full Text] [Related]

  • 6. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
    [Abstract] [Full Text] [Related]

  • 7. Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.
    Mori T, Doi R, Kida A, Nagai K, Kami K, Ito D, Toyoda E, Kawaguchi Y, Uemoto S.
    J Surg Res; 2007 Oct 01; 142(2):281-6. PubMed ID: 17640673
    [Abstract] [Full Text] [Related]

  • 8. Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro.
    Bai J, Sui J, Demirjian A, Vollmer CM, Marasco W, Callery MP.
    Cancer Res; 2005 Mar 15; 65(6):2344-52. PubMed ID: 15781649
    [Abstract] [Full Text] [Related]

  • 9. Sensitization of pancreatic carcinoma cells for gamma-irradiation-induced apoptosis by XIAP inhibition.
    Giagkousiklidis S, Vellanki SH, Debatin KM, Fulda S.
    Oncogene; 2007 Oct 25; 26(49):7006-16. PubMed ID: 17471230
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.
    Fulda S, Meyer E, Debatin KM.
    Oncogene; 2002 Apr 04; 21(15):2283-94. PubMed ID: 11948412
    [Abstract] [Full Text] [Related]

  • 11. Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family.
    Basu A, Castle VP, Bouziane M, Bhalla K, Haldar S.
    Cancer Res; 2006 Apr 15; 66(8):4309-18. PubMed ID: 16618756
    [Abstract] [Full Text] [Related]

  • 12. Synergistic antitumor activity of XIAP-shRNA and TRAIL expressed by oncolytic adenoviruses in experimental HCC.
    Pan Q, Liu B, Liu J, Cai R, Liu X, Qian C.
    Acta Oncol; 2008 Apr 15; 47(1):135-44. PubMed ID: 17934893
    [Abstract] [Full Text] [Related]

  • 13. Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells.
    Shi RX, Ong CN, Shen HM.
    Cancer Res; 2005 Sep 01; 65(17):7815-23. PubMed ID: 16140950
    [Abstract] [Full Text] [Related]

  • 14. Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells.
    Lippa MS, Strockbine LD, Le TT, Branstetter DG, Strathdee CA, Holland PM.
    Apoptosis; 2007 Aug 01; 12(8):1465-78. PubMed ID: 17440816
    [Abstract] [Full Text] [Related]

  • 15. Chetomin induces degradation of XIAP and enhances TRAIL sensitivity in urogenital cancer cells.
    Yano K, Horinaka M, Yoshida T, Yasuda T, Taniguchi H, Goda AE, Wakada M, Yoshikawa S, Nakamura T, Kawauchi A, Miki T, Sakai T.
    Int J Oncol; 2011 Feb 01; 38(2):365-74. PubMed ID: 21165560
    [Abstract] [Full Text] [Related]

  • 16. Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway.
    Naumann I, Kappler R, von Schweinitz D, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 May 15; 17(10):3204-18. PubMed ID: 21459798
    [Abstract] [Full Text] [Related]

  • 17. A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia.
    Loeder S, Zenz T, Schnaiter A, Mertens D, Winkler D, Döhner H, Debatin KM, Stilgenbauer S, Fulda S.
    Cancer Res; 2009 Dec 01; 69(23):8977-86. PubMed ID: 19920200
    [Abstract] [Full Text] [Related]

  • 18. Targeting of XIAP combined with systemic mesenchymal stem cell-mediated delivery of sTRAIL ligand inhibits metastatic growth of pancreatic carcinoma cells.
    Mohr A, Albarenque SM, Deedigan L, Yu R, Reidy M, Fulda S, Zwacka RM.
    Stem Cells; 2010 Nov 01; 28(11):2109-20. PubMed ID: 20882532
    [Abstract] [Full Text] [Related]

  • 19. Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice.
    Naumann U, Bähr O, Wolburg H, Altenberend S, Wick W, Liston P, Ashkenazi A, Weller M.
    Gene Ther; 2007 Jan 01; 14(2):147-61. PubMed ID: 16957768
    [Abstract] [Full Text] [Related]

  • 20. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis.
    Chawla-Sarkar M, Bae SI, Reu FJ, Jacobs BS, Lindner DJ, Borden EC.
    Cell Death Differ; 2004 Aug 01; 11(8):915-23. PubMed ID: 15118763
    [Abstract] [Full Text] [Related]

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