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Journal Abstract Search

301 related items for PubMed ID: 18829893

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  • 2. 4-phenylbutyrate enhances the cell surface expression and the transport capacity of wild-type and mutated bile salt export pumps.
    Hayashi H, Sugiyama Y.
    Hepatology; 2007 Jun; 45(6):1506-16. PubMed ID: 17538928
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  • 4. Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases.
    Lam P, Pearson CL, Soroka CJ, Xu S, Mennone A, Boyer JL.
    Am J Physiol Cell Physiol; 2007 Nov; 293(5):C1709-16. PubMed ID: 17855769
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  • 5. Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.
    Kagawa T, Watanabe N, Mochizuki K, Numari A, Ikeno Y, Itoh J, Tanaka H, Arias IM, Mine T.
    Am J Physiol Gastrointest Liver Physiol; 2008 Jan; 294(1):G58-67. PubMed ID: 17947449
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  • 6. AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.
    Hayashi H, Inamura K, Aida K, Naoi S, Horikawa R, Nagasaka H, Takatani T, Fukushima T, Hattori A, Yabuki T, Horii I, Sugiyama Y.
    Hepatology; 2012 Jun; 55(6):1889-900. PubMed ID: 22262466
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  • 7. Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.
    Hayashi H, Takada T, Suzuki H, Akita H, Sugiyama Y.
    Hepatology; 2005 Apr; 41(4):916-24. PubMed ID: 15791618
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  • 8. Successful mutation-specific chaperone therapy with 4-phenylbutyrate in a child with progressive familial intrahepatic cholestasis type 2.
    Gonzales E, Grosse B, Cassio D, Davit-Spraul A, Fabre M, Jacquemin E.
    J Hepatol; 2012 Sep; 57(3):695-8. PubMed ID: 22609309
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  • 10. Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2.
    Misawa T, Hayashi H, Sugiyama Y, Hashimoto Y.
    Bioorg Med Chem; 2012 May 01; 20(9):2940-9. PubMed ID: 22464344
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  • 11. Targeted pharmacotherapy in progressive familial intrahepatic cholestasis type 2: Evidence for improvement of cholestasis with 4-phenylbutyrate.
    Gonzales E, Grosse B, Schuller B, Davit-Spraul A, Conti F, Guettier C, Cassio D, Jacquemin E.
    Hepatology; 2015 Aug 01; 62(2):558-66. PubMed ID: 25716872
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  • 12. Differential roles of ubiquitination in the degradation mechanism of cell surface-resident bile salt export pump and multidrug resistance-associated protein 2.
    Aida K, Hayashi H, Inamura K, Mizuno T, Sugiyama Y.
    Mol Pharmacol; 2014 Mar 01; 85(3):482-91. PubMed ID: 24378332
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  • 16. Clinical phenotype and molecular analysis of a homozygous ABCB11 mutation responsible for progressive infantile cholestasis.
    Imagawa K, Hayashi H, Sabu Y, Tanikawa K, Fujishiro J, Kajikawa D, Wada H, Kudo T, Kage M, Kusuhara H, Sumazaki R.
    J Hum Genet; 2018 May 01; 63(5):569-577. PubMed ID: 29507376
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  • 17. Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families.
    Strautnieks SS, Byrne JA, Pawlikowska L, Cebecauerová D, Rayner A, Dutton L, Meier Y, Antoniou A, Stieger B, Arnell H, Ozçay F, Al-Hussaini HF, Bassas AF, Verkade HJ, Fischler B, Németh A, Kotalová R, Shneider BL, Cielecka-Kuszyk J, McClean P, Whitington PF, Sokal E, Jirsa M, Wali SH, Jankowska I, Pawłowska J, Mieli-Vergani G, Knisely AS, Bull LN, Thompson RJ.
    Gastroenterology; 2008 Apr 01; 134(4):1203-14. PubMed ID: 18395098
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  • 19. A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump.
    Plass JR, Mol O, Heegsma J, Geuken M, de Bruin J, Elling G, Müller M, Faber KN, Jansen PL.
    J Hepatol; 2004 Jan 01; 40(1):24-30. PubMed ID: 14672610
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