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298 related items for PubMed ID: 18845636

  • 1. Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to follicle-stimulating hormone.
    Alam H, Weck J, Maizels E, Park Y, Lee EJ, Ashcroft M, Hunzicker-Dunn M.
    Endocrinology; 2009 Feb; 150(2):915-28. PubMed ID: 18845636
    [Abstract] [Full Text] [Related]

  • 2. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
    Alam H, Maizels ET, Park Y, Ghaey S, Feiger ZJ, Chandel NS, Hunzicker-Dunn M.
    J Biol Chem; 2004 May 07; 279(19):19431-40. PubMed ID: 14982927
    [Abstract] [Full Text] [Related]

  • 3. Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells.
    Gonzalez-Robayna IJ, Falender AE, Ochsner S, Firestone GL, Richards JS.
    Mol Endocrinol; 2000 Aug 07; 14(8):1283-300. PubMed ID: 10935551
    [Abstract] [Full Text] [Related]

  • 4. Follicle-stimulating hormone and insulin-like growth factor I synergistically induce up-regulation of cartilage link protein (Crtl1) via activation of phosphatidylinositol-dependent kinase/Akt in rat granulosa cells.
    Sun GW, Kobayashi H, Suzuki M, Kanayama N, Terao T.
    Endocrinology; 2003 Mar 07; 144(3):793-801. PubMed ID: 12586755
    [Abstract] [Full Text] [Related]

  • 5. Extracellular Signal-regulated Kinase (ERK)-dependent Phosphorylation of Y-Box-binding Protein 1 (YB-1) Enhances Gene Expression in Granulosa Cells in Response to Follicle-stimulating Hormone (FSH).
    Donaubauer EM, Hunzicker-Dunn ME.
    J Biol Chem; 2016 Jun 03; 291(23):12145-60. PubMed ID: 27080258
    [Abstract] [Full Text] [Related]

  • 6. Insulin-like growth factor-I prevents hypoxia-inducible factor-1 alpha-dependent G1/S arrest by activating cyclin E/cyclin-dependent kinase2 via the phoshatidylinositol-3 kinase/AKT/forkhead box O1/Cdkn1b pathway in porcine granulosa cells†.
    Li C, Liu Z, Zhou J, Meng X, Liu S, Li W, Zhang X, Zhou J, Yao W, Dong C, Cao Y, Li R, Chen B, Jiang A, Jiang Y, Ning C, Zhao F, Wei Y, Sun SC, Tao J, Wu W, Shen M, Liu H.
    Biol Reprod; 2020 Feb 12; 102(1):116-132. PubMed ID: 31435642
    [Abstract] [Full Text] [Related]

  • 7. Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.
    Richards JS, Sharma SC, Falender AE, Lo YH.
    Mol Endocrinol; 2002 Mar 12; 16(3):580-99. PubMed ID: 11875118
    [Abstract] [Full Text] [Related]

  • 8. Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad.
    Park Y, Maizels ET, Feiger ZJ, Alam H, Peters CA, Woodruff TK, Unterman TG, Lee EJ, Jameson JL, Hunzicker-Dunn M.
    J Biol Chem; 2005 Mar 11; 280(10):9135-48. PubMed ID: 15613482
    [Abstract] [Full Text] [Related]

  • 9. Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells.
    Kayampilly PP, Menon KM.
    Endocrinology; 2007 Aug 11; 148(8):3950-7. PubMed ID: 17510244
    [Abstract] [Full Text] [Related]

  • 10. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG.
    J Pathol; 2005 Mar 11; 205(4):530-6. PubMed ID: 15714461
    [Abstract] [Full Text] [Related]

  • 11. FSH preserves the viability of hypoxic granulosa cells via activating the HIF-1α-GAS6-Axl-Akt pathway.
    Li C, Fu C, He T, Liu Z, Zhou J, Wu G, Liu H, Shen M.
    J Cell Physiol; 2024 Feb 11; 239(2):e31162. PubMed ID: 37994152
    [Abstract] [Full Text] [Related]

  • 12. Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy.
    Shen M, Jiang Y, Guan Z, Cao Y, Li L, Liu H, Sun SC.
    Autophagy; 2017 Aug 03; 13(8):1364-1385. PubMed ID: 28598230
    [Abstract] [Full Text] [Related]

  • 13. Involvement of FoxO1 in the effects of follicle-stimulating hormone on inhibition of apoptosis in mouse granulosa cells.
    Shen M, Liu Z, Li B, Teng Y, Zhang J, Tang Y, Sun SC, Liu H.
    Cell Death Dis; 2014 Oct 16; 5(10):e1475. PubMed ID: 25321482
    [Abstract] [Full Text] [Related]

  • 14. Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFbeta1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells.
    Chen YJ, Hsiao PW, Lee MT, Mason JI, Ke FC, Hwang JJ.
    J Endocrinol; 2007 Feb 16; 192(2):405-19. PubMed ID: 17283241
    [Abstract] [Full Text] [Related]

  • 15. IL-6 Promotes FSH-Induced VEGF Expression Through JAK/STAT3 Signaling Pathway in Bovine Granulosa Cells.
    Yang M, Wang L, Wang X, Wang X, Yang Z, Li J.
    Cell Physiol Biochem; 2017 Feb 16; 44(1):293-302. PubMed ID: 29132131
    [Abstract] [Full Text] [Related]

  • 16. Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.
    Yang XM, Wang YS, Zhang J, Li Y, Xu JF, Zhu J, Zhao W, Chu DK, Wiedemann P.
    Invest Ophthalmol Vis Sci; 2009 Apr 16; 50(4):1873-9. PubMed ID: 19098317
    [Abstract] [Full Text] [Related]

  • 17. Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1.
    Law NC, Weck J, Kyriss B, Nilson JH, Hunzicker-Dunn M.
    Mol Endocrinol; 2013 Aug 16; 27(8):1295-310. PubMed ID: 23754802
    [Abstract] [Full Text] [Related]

  • 18. Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
    Pore N, Jiang Z, Shu HK, Bernhard E, Kao GD, Maity A.
    Mol Cancer Res; 2006 Jul 16; 4(7):471-9. PubMed ID: 16849522
    [Abstract] [Full Text] [Related]

  • 19. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL.
    Cancer Res; 2000 Mar 15; 60(6):1541-5. PubMed ID: 10749120
    [Abstract] [Full Text] [Related]

  • 20. IGF-I signaling is essential for FSH stimulation of AKT and steroidogenic genes in granulosa cells.
    Zhou P, Baumgarten SC, Wu Y, Bennett J, Winston N, Hirshfeld-Cytron J, Stocco C.
    Mol Endocrinol; 2013 Mar 15; 27(3):511-23. PubMed ID: 23340251
    [Abstract] [Full Text] [Related]


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