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Journal Abstract Search

383 related items for PubMed ID: 18851976

  • 1. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
    Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M.
    J Mol Biol; 2008 Dec 19; 384(3):673-89. PubMed ID: 18851976
    [Abstract] [Full Text] [Related]

  • 2. Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
    Cossu F, Milani M, Mastrangelo E, Vachette P, Servida F, Lecis D, Canevari G, Delia D, Drago C, Rizzo V, Manzoni L, Seneci P, Scolastico C, Bolognesi M.
    J Mol Biol; 2009 Sep 25; 392(3):630-44. PubMed ID: 19393243
    [Abstract] [Full Text] [Related]

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  • 4. Theoretical studies on the interactions of XIAP-BIR3 domain with bicyclic and tricyclic core monovalent Smac mimetics.
    Ling B, Dong L, Zhang R, Wang Z, Liu Y, Liu C.
    J Mol Graph Model; 2010 Nov 25; 29(3):354-62. PubMed ID: 20980180
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  • 7. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.
    Nikolovska-Coleska Z, Meagher JL, Jiang S, Kawamoto SA, Gao W, Yi H, Qin D, Roller PP, Stuckey JA, Wang S.
    Anal Biochem; 2008 Mar 01; 374(1):87-98. PubMed ID: 18023397
    [Abstract] [Full Text] [Related]

  • 8. The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
    Kulathila R, Vash B, Sage D, Cornell-Kennon S, Wright K, Koehn J, Stams T, Clark K, Price A.
    Acta Crystallogr D Biol Crystallogr; 2009 Jan 01; 65(Pt 1):58-66. PubMed ID: 19153467
    [Abstract] [Full Text] [Related]

  • 9. Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).
    Franklin MC, Kadkhodayan S, Ackerly H, Alexandru D, Distefano MD, Elliott LO, Flygare JA, Mausisa G, Okawa DC, Ong D, Vucic D, Deshayes K, Fairbrother WJ.
    Biochemistry; 2003 Jul 15; 42(27):8223-31. PubMed ID: 12846571
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  • 10. Conformational selection, dynamic restriction and the hydrophobic effect coupled to stabilization of the BIR3 domain of the human X-linked inhibitor of apoptosis protein by the tetrapeptide AVPI.
    de Souza TL, Sanches D, Gonçalves RB, da RochaPita SS, Pascutti PG, Bianconi ML, de Almeida FC, Silva JL, de Oliveira AC.
    Biophys Chem; 2010 Nov 15; 152(1-3):99-108. PubMed ID: 20843595
    [Abstract] [Full Text] [Related]

  • 11. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
    Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SW.
    Nature; 2010 Nov 15; 408(6815):1004-8. PubMed ID: 11140637
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  • 12. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
    Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S.
    J Med Chem; 2004 May 06; 47(10):2430-40. PubMed ID: 15115387
    [Abstract] [Full Text] [Related]

  • 13. Protein-protein recognition as a first step towards the inhibition of XIAP and Survivin anti-apoptotic proteins.
    Obiol-Pardo C, Granadino-Roldán JM, Rubio-Martinez J.
    J Mol Recognit; 2008 May 06; 21(3):190-204. PubMed ID: 18438971
    [Abstract] [Full Text] [Related]

  • 14. Biochemical basis for enhanced binding of peptide dimers to X-linked inhibitor of apoptosis protein.
    Splan KE, Allen JE, McLendon GL.
    Biochemistry; 2007 Oct 23; 46(42):11938-44. PubMed ID: 17910418
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  • 15. Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.
    Nikolovska-Coleska Z, Wang R, Fang X, Pan H, Tomita Y, Li P, Roller PP, Krajewski K, Saito NG, Stuckey JA, Wang S.
    Anal Biochem; 2004 Sep 15; 332(2):261-73. PubMed ID: 15325294
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  • 17. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D, Franklin MC, Wallweber HJ, Das K, Eckelman BP, Shin H, Elliott LO, Kadkhodayan S, Deshayes K, Salvesen GS, Fairbrother WJ.
    Biochem J; 2005 Jan 01; 385(Pt 1):11-20. PubMed ID: 15485396
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  • 18. Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library.
    Sweeney MC, Wang X, Park J, Liu Y, Pei D.
    Biochemistry; 2006 Dec 12; 45(49):14740-8. PubMed ID: 17144666
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  • 19. Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.
    Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S.
    J Med Chem; 2004 Aug 12; 47(17):4147-50. PubMed ID: 15293984
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  • 20. Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
    Cossu F, Milani M, Vachette P, Malvezzi F, Grassi S, Lecis D, Delia D, Drago C, Seneci P, Bolognesi M, Mastrangelo E.
    PLoS One; 2012 Aug 12; 7(11):e49527. PubMed ID: 23166698
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