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647 related items for PubMed ID: 18854359

  • 1. Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.
    Kohler EM, Chandra SH, Behrens J, Schneikert J.
    Hum Mol Genet; 2009 Jan 15; 18(2):213-26. PubMed ID: 18854359
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  • 2. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM, Brauburger K, Behrens J, Schneikert J.
    Oncogene; 2010 Mar 18; 29(11):1663-71. PubMed ID: 19966865
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  • 3. APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
    Latchford A, Volikos E, Johnson V, Rogers P, Suraweera N, Tomlinson I, Phillips R, Silver A.
    Hum Mol Genet; 2007 Jan 01; 16(1):78-82. PubMed ID: 17135276
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  • 4. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
    Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP.
    Oncogene; 2003 Jul 03; 22(27):4257-65. PubMed ID: 12833148
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  • 5. APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC.
    Schneikert J, Brauburger K, Behrens J.
    Hum Mol Genet; 2011 Sep 15; 20(18):3554-64. PubMed ID: 21665989
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  • 8. Colorectal cancer and genetic alterations in the Wnt pathway.
    Segditsas S, Tomlinson I.
    Oncogene; 2006 Dec 04; 25(57):7531-7. PubMed ID: 17143297
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  • 9. Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours.
    Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J.
    Hum Mol Genet; 2008 Jul 01; 17(13):1978-87. PubMed ID: 18387968
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  • 12. Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.
    Segditsas S, Sieber OM, Rowan A, Setien F, Neale K, Phillips RK, Ward R, Esteller M, Tomlinson IP.
    Exp Mol Pathol; 2008 Dec 01; 85(3):201-6. PubMed ID: 18977219
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  • 13. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A, Kullmann F.
    Med Klin (Munich); 2003 Dec 15; 98(12):776-82. PubMed ID: 14685680
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  • 14. Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer.
    Ruiz-Ponte C, Vega A, Carracedo A, Barros F.
    Hum Mutat; 2001 Oct 15; 18(4):355. PubMed ID: 11668620
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  • 15. Identification of Familial Adenomatous Polyposis carriers among children with desmoid tumours.
    Kattentidt Mouravieva AA, Geurts-Giele IR, de Krijger RR, van Noesel MM, van de Ven CP, van den Ouweland AM, Kromosoeto JN, Dinjens WN, Dubbink HJ, Smits R, Wagner A.
    Eur J Cancer; 2012 Aug 15; 48(12):1867-74. PubMed ID: 22305464
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  • 16. Subcellular localization of beta-catenin and APC proteins in colorectal preneoplastic and neoplastic lesions.
    Sena P, Saviano M, Monni S, Losi L, Roncucci L, Marzona L, De Pol A.
    Cancer Lett; 2006 Sep 28; 241(2):203-12. PubMed ID: 16298038
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  • 17. Functional characterization of the novel APC N1026S variant associated with attenuated familial adenomatous polyposis.
    Menéndez M, González S, Obrador-Hevia A, Domínguez A, Pujol MJ, Valls J, Canela N, Blanco I, Torres A, Pineda-Lucena A, Moreno V, Bachs O, Capellá G.
    Gastroenterology; 2008 Jan 28; 134(1):56-64. PubMed ID: 18166348
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  • 19. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H, Sutter C, Kadmon M, Otto HF, Von Knebel-Doeberitz M, Gebert J, Helmke BM.
    Genes Chromosomes Cancer; 2004 Oct 28; 41(2):93-8. PubMed ID: 15287021
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  • 20. Adenomatous polyposis coli alteration in digestive endocrine tumours: correlation with nuclear translocation of beta-catenin and chromosomal instability.
    Pizzi S, Azzoni C, Tamburini E, Bottarelli L, Campanini N, D'Adda T, Fellegara G, Luong TV, Pasquali C, Rossi G, Delle Fave G, Camisa R, Bordi C, Rindi G.
    Endocr Relat Cancer; 2008 Dec 28; 15(4):1013-24. PubMed ID: 18632876
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