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Journal Abstract Search

507 related items for PubMed ID: 18925943

  • 1. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
    DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, Slager AM, Burczynski ME, Dorner AJ, LaVallie ER.
    J Transl Med; 2008 Oct 16; 6():59. PubMed ID: 18925943
    [Abstract] [Full Text] [Related]

  • 2. Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells.
    Trasino SE, Kim YS, Wang TT.
    Mol Cancer Ther; 2009 Jul 16; 8(7):1934-45. PubMed ID: 19531574
    [Abstract] [Full Text] [Related]

  • 3. Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.
    Quinet EM, Savio DA, Halpern AR, Chen L, Schuster GU, Gustafsson JA, Basso MD, Nambi P.
    Mol Pharmacol; 2006 Oct 16; 70(4):1340-9. PubMed ID: 16825483
    [Abstract] [Full Text] [Related]

  • 4. Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
    Lund EG, Peterson LB, Adams AD, Lam MH, Burton CA, Chin J, Guo Q, Huang S, Latham M, Lopez JC, Menke JG, Milot DP, Mitnaul LJ, Rex-Rabe SE, Rosa RL, Tian JY, Wright SD, Sparrow CP.
    Biochem Pharmacol; 2006 Feb 14; 71(4):453-63. PubMed ID: 16325781
    [Abstract] [Full Text] [Related]

  • 5. Effects of lipid-lowering drugs on reverse cholesterol transport gene expressions in peripheral blood mononuclear and HepG2 cells.
    Genvigir FD, Rodrigues AC, Cerda A, Arazi SS, Willrich MA, Oliveira R, Hirata MH, Dorea EL, Bernik MM, Curi R, Hirata RD.
    Pharmacogenomics; 2010 Sep 14; 11(9):1235-46. PubMed ID: 20860464
    [Abstract] [Full Text] [Related]

  • 6. Ligation of RAGE with ligand S100B attenuates ABCA1 expression in monocytes.
    Kumar P, Raghavan S, Shanmugam G, Shanmugam N.
    Metabolism; 2013 Aug 14; 62(8):1149-58. PubMed ID: 23523156
    [Abstract] [Full Text] [Related]

  • 7. Safety, pharmacokinetics, and pharmacodynamics of single doses of LXR-623, a novel liver X-receptor agonist, in healthy participants.
    Katz A, Udata C, Ott E, Hickey L, Burczynski ME, Burghart P, Vesterqvist O, Meng X.
    J Clin Pharmacol; 2009 Jun 14; 49(6):643-9. PubMed ID: 19398602
    [Abstract] [Full Text] [Related]

  • 8. [Decline of ATP-binding cassette transporter G1 expressions with a liver X receptor-independent pathway in patients with type 2 diabetes].
    Wang HJ, Zhao XS, Sun HY, Chen LF, Yan XW.
    Beijing Da Xue Xue Bao Yi Xue Ban; 2014 Dec 18; 46(6):899-905. PubMed ID: 25512280
    [Abstract] [Full Text] [Related]

  • 9. Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells.
    Ma X, Li SF, Qin ZS, Ye J, Zhao ZL, Fang HH, Yao ZW, Gu MN, Hu YW.
    Cardiovasc Pathol; 2015 Dec 18; 24(4):230-5. PubMed ID: 25600616
    [Abstract] [Full Text] [Related]

  • 10. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.
    Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.
    J Lipid Res; 2003 Sep 18; 44(9):1728-36. PubMed ID: 12777468
    [Abstract] [Full Text] [Related]

  • 11. Pharmacological characterization of a novel liver X receptor agonist with partial LXRα activity and a favorable window in nonhuman primates.
    Kirchgessner TG, Martin R, Sleph P, Grimm D, Liu X, Lupisella J, Smalley J, Narayanan R, Xie Y, Ostrowski J, Cantor GH, Mohan R, Kick E.
    J Pharmacol Exp Ther; 2015 Feb 18; 352(2):305-14. PubMed ID: 25467132
    [Abstract] [Full Text] [Related]

  • 12. Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue.
    Ulven SM, Dalen KT, Gustafsson JA, Nebb HI.
    J Lipid Res; 2004 Nov 18; 45(11):2052-62. PubMed ID: 15292368
    [Abstract] [Full Text] [Related]

  • 13. A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux.
    Sparrow CP, Baffic J, Lam MH, Lund EG, Adams AD, Fu X, Hayes N, Jones AB, Macnaul KL, Ondeyka J, Singh S, Wang J, Zhou G, Moller DE, Wright SD, Menke JG.
    J Biol Chem; 2002 Mar 22; 277(12):10021-7. PubMed ID: 11790770
    [Abstract] [Full Text] [Related]

  • 14. Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism.
    Li Y, Bolten C, Bhat BG, Woodring-Dietz J, Li S, Prayaga SK, Xia C, Lala DS.
    Mol Endocrinol; 2002 Mar 22; 16(3):506-14. PubMed ID: 11875109
    [Abstract] [Full Text] [Related]

  • 15. PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXRα through the IGF-I-mediated signaling pathway.
    Tang SL, Chen WJ, Yin K, Zhao GJ, Mo ZC, Lv YC, Ouyang XP, Yu XH, Kuang HJ, Jiang ZS, Fu YC, Tang CK.
    Atherosclerosis; 2012 Jun 22; 222(2):344-54. PubMed ID: 22503545
    [Abstract] [Full Text] [Related]

  • 16. Atorvastatin inhibits ABCA1 expression and cholesterol efflux in THP-1 macrophages by an LXR-dependent pathway.
    Qiu G, Hill JS.
    J Cardiovasc Pharmacol; 2008 Apr 22; 51(4):388-95. PubMed ID: 18427282
    [Abstract] [Full Text] [Related]

  • 17. Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.
    Yan W, Zhang T, Cheng J, Zhou X, Qu X, Hu H.
    Pharmacology; 2010 Apr 22; 86(5-6):306-12. PubMed ID: 21071998
    [Abstract] [Full Text] [Related]

  • 18. LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells.
    Murthy S, Born E, Mathur SN, Field FJ.
    J Lipid Res; 2002 Jul 22; 43(7):1054-64. PubMed ID: 12091489
    [Abstract] [Full Text] [Related]

  • 19. TGF-beta1 up-regulates expression of ABCA1, ABCG1 and SR-BI through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells.
    Hu YW, Wang Q, Ma X, Li XX, Liu XH, Xiao J, Liao DF, Xiang J, Tang CK.
    J Atheroscler Thromb; 2010 May 22; 17(5):493-502. PubMed ID: 20057170
    [Abstract] [Full Text] [Related]

  • 20. Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.
    Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-Kondo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K.
    Atherosclerosis; 2011 Nov 22; 219(1):141-50. PubMed ID: 21862012
    [Abstract] [Full Text] [Related]

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