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Journal Abstract Search


332 related items for PubMed ID: 18925944

  • 1. Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.
    Kiyosawa N, Kwekel JC, Burgoon LD, Dere E, Williams KJ, Tashiro C, Chittim B, Zacharewski TR.
    BMC Genomics; 2008 Oct 16; 9():487. PubMed ID: 18925944
    [Abstract] [Full Text] [Related]

  • 2. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
    Kiyosawa N, Kwekel JC, Burgoon LD, Williams KJ, Tashiro C, Chittim B, Zacharewski TR.
    Toxicol Sci; 2008 Feb 16; 101(2):350-63. PubMed ID: 17984292
    [Abstract] [Full Text] [Related]

  • 3. Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).
    Sakai H, Iwata H, Kim EY, Tsydenova O, Miyazaki N, Petrov EA, Batoev VB, Tanabe S.
    Toxicol Sci; 2006 Nov 16; 94(1):57-70. PubMed ID: 16929008
    [Abstract] [Full Text] [Related]

  • 4. o-p'-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague-Dawley rats.
    Kwekel JC, Forgacs AL, Williams KJ, Zacharewski TR.
    Toxicol Appl Pharmacol; 2013 Dec 15; 273(3):532-41. PubMed ID: 24096037
    [Abstract] [Full Text] [Related]

  • 5. Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers.
    Kazantseva YA, Yarushkin AA, Pustylnyak VO.
    Toxicol Appl Pharmacol; 2013 Sep 01; 271(2):137-43. PubMed ID: 23684557
    [Abstract] [Full Text] [Related]

  • 6. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
    Slatter JG, Cheng O, Cornwell PD, de Souza A, Rockett J, Rushmore T, Hartley D, Evers R, He Y, Dai X, Hu R, Caguyong M, Roberts CJ, Castle J, Ulrich RG.
    Xenobiotica; 2006 Sep 01; 36(10-11):902-37. PubMed ID: 17118914
    [Abstract] [Full Text] [Related]

  • 7. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY, Klaassen CD.
    Biochim Biophys Acta; 2016 Sep 01; 1859(9):1198-1217. PubMed ID: 27113289
    [Abstract] [Full Text] [Related]

  • 8. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB, Leghait J, Lacroix MZ, Lasserre F, Pineau T, Viguié C, Martin PG.
    Biochem Pharmacol; 2013 Oct 01; 86(7):997-1039. PubMed ID: 23962444
    [Abstract] [Full Text] [Related]

  • 9. Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor.
    Wang Z, Li X, Wu Q, Lamb JC, Klaunig JE.
    J Appl Toxicol; 2017 Aug 01; 37(8):967-975. PubMed ID: 28218408
    [Abstract] [Full Text] [Related]

  • 10. Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR.
    Tojima H, Kakizaki S, Yamazaki Y, Takizawa D, Horiguchi N, Sato K, Mori M.
    Toxicol Lett; 2012 Aug 03; 212(3):288-97. PubMed ID: 22698814
    [Abstract] [Full Text] [Related]

  • 11. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
    Wyde ME, Bartolucci E, Ueda A, Zhang H, Yan B, Negishi M, You L.
    Mol Pharmacol; 2003 Aug 03; 64(2):474-81. PubMed ID: 12869653
    [Abstract] [Full Text] [Related]

  • 12. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG.
    Toxicol Sci; 2014 Jun 03; 139(2):501-11. PubMed ID: 24690595
    [Abstract] [Full Text] [Related]

  • 13. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 14. Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors.
    Rouquié D, Tinwell H, Blanck O, Schorsch F, Geter D, Wason S, Bars R.
    Regul Toxicol Pharmacol; 2014 Dec 01; 70(3):673-80. PubMed ID: 25455223
    [Abstract] [Full Text] [Related]

  • 15. Editor's Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver.
    Li CY, Cheng SL, Bammler TK, Cui JY.
    Toxicol Sci; 2016 Oct 01; 153(2):282-302. PubMed ID: 27413110
    [Abstract] [Full Text] [Related]

  • 16. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.
    Hartley DP, Dai X, He YD, Carlini EJ, Wang B, Huskey SE, Ulrich RG, Rushmore TH, Evers R, Evans DC.
    Mol Pharmacol; 2004 May 01; 65(5):1159-71. PubMed ID: 15102944
    [Abstract] [Full Text] [Related]

  • 17. Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.
    Di Lorenzo D, Villa R, Biasiotto G, Belloli S, Ruggeri G, Albertini A, Apostoli P, Raviscioni M, Ciana P, Maggi A.
    Endocrinology; 2002 Dec 01; 143(12):4544-51. PubMed ID: 12446581
    [Abstract] [Full Text] [Related]

  • 18. CAR and PXR: xenosensors of endocrine disrupters?
    Kretschmer XC, Baldwin WS.
    Chem Biol Interact; 2005 Aug 15; 155(3):111-28. PubMed ID: 16054614
    [Abstract] [Full Text] [Related]

  • 19. Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl)ethane.
    Medina-Díaz IM, Arteaga-Illán G, de León MB, Cisneros B, Sierra-Santoyo A, Vega L, Gonzalez FJ, Elizondo G.
    Drug Metab Dispos; 2007 Jan 15; 35(1):95-102. PubMed ID: 17035600
    [Abstract] [Full Text] [Related]

  • 20. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
    Roth A, Looser R, Kaufmann M, Meyer UA.
    Pharmacogenet Genomics; 2008 Apr 15; 18(4):325-37. PubMed ID: 18334917
    [Abstract] [Full Text] [Related]


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