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196 related items for PubMed ID: 1893372

  • 1. Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkylation in vitro and its inhibition by isothiocyanates.
    Guo Z, Smith TJ, Thomas PE, Yang CS.
    Cancer Res; 1991 Sep 15; 51(18):4798-803. PubMed ID: 1893372
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
    Guo Z, Smith TJ, Wang E, Eklind KI, Chung FL, Yang CS.
    Carcinogenesis; 1993 Jun 15; 14(6):1167-73. PubMed ID: 8508504
    [Abstract] [Full Text] [Related]

  • 5. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 15; 18(8):1577-84. PubMed ID: 9276633
    [Abstract] [Full Text] [Related]

  • 6. Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
    Smith TJ, Guo Z, Hong JY, Ning SM, Thomas PE, Yang CS.
    Carcinogenesis; 1992 Aug 15; 13(8):1409-14. PubMed ID: 1499091
    [Abstract] [Full Text] [Related]

  • 7. Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Morse MA, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Jun 01; 49(11):2894-7. PubMed ID: 2720649
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.
    Morse MA, Wang CX, Stoner GD, Mandal S, Conran PB, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Feb 01; 49(3):549-53. PubMed ID: 2910476
    [Abstract] [Full Text] [Related]

  • 9. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun 01; 12(6):1029-34. PubMed ID: 2044181
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates.
    Morse MA, Eklind KI, Hecht SS, Chung FL.
    IARC Sci Publ; 1991 Jun 01; (105):529-34. PubMed ID: 1855911
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system.
    Guo Z, Smith TJ, Ishizaki H, Yang CS.
    Carcinogenesis; 1991 Dec 01; 12(12):2277-82. PubMed ID: 1747927
    [Abstract] [Full Text] [Related]

  • 12. Effects of isothiocyanates on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene by hamster and rat liver microsomes.
    Hamilton SM, Teel RW.
    Anticancer Res; 1994 Dec 01; 14(3A):1089-94. PubMed ID: 8074455
    [Abstract] [Full Text] [Related]

  • 13. Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
    Guo Z, Smith TJ, Wang E, Sadrieh N, Ma Q, Thomas PE, Yang CS.
    Carcinogenesis; 1992 Dec 01; 13(12):2205-10. PubMed ID: 1473225
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 01; 17(4):809-13. PubMed ID: 8625495
    [Abstract] [Full Text] [Related]

  • 15. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME, Koenig LA, Hecht SS.
    Carcinogenesis; 1997 Sep 01; 18(9):1715-22. PubMed ID: 9328166
    [Abstract] [Full Text] [Related]

  • 16. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME, Foiles PG, Miglietta LM, Hecht SS.
    Cancer Res; 1997 Jan 15; 57(2):259-66. PubMed ID: 9000565
    [Abstract] [Full Text] [Related]

  • 17. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ, Stoner GD, Yang CS.
    Cancer Res; 1995 Dec 01; 55(23):5566-73. PubMed ID: 7585636
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice.
    Morse MA, Eklind KI, Hecht SS, Jordan KG, Choi CI, Desai DH, Amin SG, Chung FL.
    Cancer Res; 1991 Apr 01; 51(7):1846-50. PubMed ID: 2004368
    [Abstract] [Full Text] [Related]

  • 19. Factors regulating activation and DNA alkylation by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and nitrosodimethylamine in rat lung and isolated lung cells, and the relationship to carcinogenicity.
    Devereux TR, Anderson MW, Belinsky SA.
    Cancer Res; 1988 Aug 01; 48(15):4215-21. PubMed ID: 3390815
    [Abstract] [Full Text] [Related]

  • 20. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 01; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

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