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Journal Abstract Search


387 related items for PubMed ID: 18937219

  • 1. A polylinker approach to reductive loop swaps in modular polyketide synthases.
    Kellenberger L, Galloway IS, Sauter G, Böhm G, Hanefeld U, Cortés J, Staunton J, Leadlay PF.
    Chembiochem; 2008 Nov 03; 9(16):2740-9. PubMed ID: 18937219
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  • 2. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C.
    Biochemistry; 2004 Nov 09; 43(44):13892-8. PubMed ID: 15518537
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  • 4. A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.
    Reid R, Piagentini M, Rodriguez E, Ashley G, Viswanathan N, Carney J, Santi DV, Hutchinson CR, McDaniel R.
    Biochemistry; 2003 Jan 14; 42(1):72-9. PubMed ID: 12515540
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  • 7. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
    Lau J, Fu H, Cane DE, Khosla C.
    Biochemistry; 1999 Feb 02; 38(5):1643-51. PubMed ID: 9931032
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  • 9. The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.
    Keatinge-Clay AT, Stroud RM.
    Structure; 2006 Apr 02; 14(4):737-48. PubMed ID: 16564177
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  • 10. High-throughput mutagenesis to evaluate models of stereochemical control in ketoreductase domains from the erythromycin polyketide synthase.
    O'Hare HM, Baerga-Ortiz A, Popovic B, Spencer JB, Leadlay PF.
    Chem Biol; 2006 Mar 02; 13(3):287-96. PubMed ID: 16638534
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  • 11. Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain.
    Soehano I, Yang L, Ding F, Sun H, Low ZJ, Liu X, Liang ZX.
    Org Biomol Chem; 2014 Nov 14; 12(42):8542-9. PubMed ID: 25238086
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  • 12. Identification of domains within megalomicin and erythromycin polyketide synthase modules responsible for differences in polyketide production levels in Escherichia coli.
    Murli S, Piagentini M, McDaniel R, Hutchinson CR.
    Biochemistry; 2004 Dec 21; 43(50):15884-90. PubMed ID: 15595843
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  • 13. Molecular basis of Celmer's rules: the role of two ketoreductase domains in the control of chirality by the erythromycin modular polyketide synthase.
    Holzbaur IE, Harris RC, Bycroft M, Cortes J, Bisang C, Staunton J, Rudd BA, Leadlay PF.
    Chem Biol; 1999 Apr 21; 6(4):189-95. PubMed ID: 10099131
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  • 14. Chain initiation on type I modular polyketide synthases revealed by limited proteolysis and ion-trap mass spectrometry.
    Hong H, Appleyard AN, Siskos AP, Garcia-Bernardo J, Staunton J, Leadlay PF.
    FEBS J; 2005 May 21; 272(10):2373-87. PubMed ID: 15885088
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  • 17. Broad substrate specificity of ketoreductases derived from modular polyketide synthases.
    Bali S, O'Hare HM, Weissman KJ.
    Chembiochem; 2006 Mar 21; 7(3):478-84. PubMed ID: 16453348
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  • 20. Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes.
    Menzella HG, Reid R, Carney JR, Chandran SS, Reisinger SJ, Patel KG, Hopwood DA, Santi DV.
    Nat Biotechnol; 2005 Sep 21; 23(9):1171-6. PubMed ID: 16116420
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