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Journal Abstract Search

353 related items for PubMed ID: 18938084

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  • 3. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
    Carotti A, Cadavid MI, Centeno NB, Esteve C, Loza MI, Martinez A, Nieto R, Raviña E, Sanz F, Segarra V, Sotelo E, Stefanachi A, Vidal B.
    J Med Chem; 2006 Jan 12; 49(1):282-99. PubMed ID: 16392813
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  • 4. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
    Baraldi PG, Tabrizi MA, Preti D, Bovero A, Romagnoli R, Fruttarolo F, Zaid NA, Moorman AR, Varani K, Gessi S, Merighi S, Borea PA.
    J Med Chem; 2004 Mar 11; 47(6):1434-47. PubMed ID: 14998332
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  • 5. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
    Stefanachi A, Brea JM, Cadavid MI, Centeno NB, Esteve C, Loza MI, Martinez A, Nieto R, Raviña E, Sanz F, Segarra V, Sotelo E, Vidal B, Carotti A.
    Bioorg Med Chem; 2008 Mar 15; 16(6):2852-69. PubMed ID: 18226909
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  • 7. Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists.
    Nieto MI, Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Rodríguez-Borges JE, Vidal B.
    Eur J Med Chem; 2010 Jul 15; 45(7):2884-92. PubMed ID: 20371139
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  • 8. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
    Kalla RV, Elzein E, Perry T, Li X, Palle V, Varkhedkar V, Gimbel A, Maa T, Zeng D, Zablocki J.
    J Med Chem; 2006 Jun 15; 49(12):3682-92. PubMed ID: 16759111
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  • 9. Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists.
    Baraldi PG, Baraldi S, Saponaro G, Preti D, Romagnoli R, Piccagli L, Cavalli A, Recanatini M, Moorman AR, Zaid AN, Varani K, Borea PA, Tabrizi MA.
    J Med Chem; 2012 Jan 26; 55(2):797-811. PubMed ID: 22148859
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  • 10. 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
    Tabrizi MA, Baraldi PG, Preti D, Romagnoli R, Saponaro G, Baraldi S, Moorman AR, Zaid AN, Varani K, Borea PA.
    Bioorg Med Chem; 2008 Mar 01; 16(5):2419-30. PubMed ID: 18077171
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  • 12. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
    Rodríguez-Borges JE, García-Mera X, Balo MC, Brea J, Caamaño O, Fernández F, López C, Loza MI, Nieto MI.
    Bioorg Med Chem; 2010 Mar 01; 18(5):2001-9. PubMed ID: 20137957
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  • 13. Development of spin-labeled probes for adenosine receptors.
    Ilas J, Pecar S, Hockemeyer J, Euler H, Kirfel A, Müller CE.
    J Med Chem; 2005 Mar 24; 48(6):2108-14. PubMed ID: 15771453
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  • 14. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
    Pastorin G, Da Ros T, Spalluto G, Deflorian F, Moro S, Cacciari B, Baraldi PG, Gessi S, Varani K, Borea PA.
    J Med Chem; 2003 Sep 25; 46(20):4287-96. PubMed ID: 13678407
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  • 15. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
    Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Nieto MI, Rodríguez-Borges JE.
    Bioorg Med Chem; 2009 Sep 15; 17(18):6755-60. PubMed ID: 19682912
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  • 16. Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.
    Elzein E, Kalla RV, Li X, Perry T, Gimbel A, Zeng D, Lustig D, Leung K, Zablocki J.
    J Med Chem; 2008 Apr 10; 51(7):2267-78. PubMed ID: 18321039
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  • 18. 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
    Borrmann T, Hinz S, Bertarelli DC, Li W, Florin NC, Scheiff AB, Müller CE.
    J Med Chem; 2009 Jul 09; 52(13):3994-4006. PubMed ID: 19569717
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  • 19. Selective, high affinity A(2B) adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines.
    Kalla RV, Elzein E, Perry T, Li X, Gimbel A, Yang M, Zeng D, Zablocki J.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1397-401. PubMed ID: 18226896
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