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274 related items for PubMed ID: 18945348
1. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease. Kanthasamy AG, Kitazawa M, Yang Y, Anantharam V, Kanthasamy A. Mol Brain; 2008 Oct 22; 1():12. PubMed ID: 18945348 [Abstract] [Full Text] [Related]
2. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration. Kitazawa M, Anantharam V, Kanthasamy AG. Neuroscience; 2003 Oct 22; 119(4):945-64. PubMed ID: 12831855 [Abstract] [Full Text] [Related]
3. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death. Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy AG. Ann N Y Acad Sci; 2004 Dec 22; 1035():271-89. PubMed ID: 15681813 [Abstract] [Full Text] [Related]
4. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease. Afeseh Ngwa H, Kanthasamy A, Anantharam V, Song C, Witte T, Houk R, Kanthasamy AG. Toxicol Appl Pharmacol; 2009 Oct 15; 240(2):273-85. PubMed ID: 19646462 [Abstract] [Full Text] [Related]
10. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models. Kanthasamy AG, Anantharam V, Zhang D, Latchoumycandane C, Jin H, Kaul S, Kanthasamy A. Free Radic Biol Med; 2006 Nov 15; 41(10):1578-89. PubMed ID: 17045926 [Abstract] [Full Text] [Related]
12. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation. Sun F, Kanthasamy A, Song C, Yang Y, Anantharam V, Kanthasamy AG. J Cell Mol Med; 2008 Dec 15; 12(6A):2467-81. PubMed ID: 18298651 [Abstract] [Full Text] [Related]
13. Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: implications for oxidative stress and environmental factors in Parkinson's disease. Kanthasamy AG, Kitazawa M, Kaul S, Yang Y, Lahiri DK, Anantharam V, Kanthasamy A. Ann N Y Acad Sci; 2003 Dec 15; 1010():683-6. PubMed ID: 15033812 [Abstract] [Full Text] [Related]
14. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration. Yang Y, Kaul S, Zhang D, Anantharam V, Kanthasamy AG. Mol Cell Neurosci; 2004 Mar 15; 25(3):406-21. PubMed ID: 15033169 [Abstract] [Full Text] [Related]