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5. Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo. Gupta R, Rao Gogineni V, Nalla AK, Chetty C, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS. Int J Oncol; 2011 Apr; 38(4):973-83. PubMed ID: 21290090 [Abstract] [Full Text] [Related]
6. RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth. Kondraganti S, Gondi CS, McCutcheon I, Dinh DH, Gujrati M, Rao JS, Olivero WC. Int J Oncol; 2006 Jun; 28(6):1353-60. PubMed ID: 16685436 [Abstract] [Full Text] [Related]
7. siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells. Subramanian R, Gondi CS, Lakka SS, Jutla A, Rao JS. Int J Oncol; 2006 Apr; 28(4):831-9. PubMed ID: 16525631 [Abstract] [Full Text] [Related]
8. Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma. Nalla AK, Gogineni VR, Gupta R, Dinh DH, Rao JS. Cell Signal; 2011 Aug; 23(8):1299-310. PubMed ID: 21426933 [Abstract] [Full Text] [Related]
9. RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. Pulukuri SM, Gondi CS, Lakka SS, Jutla A, Estes N, Gujrati M, Rao JS. J Biol Chem; 2005 Oct 28; 280(43):36529-40. PubMed ID: 16127174 [Abstract] [Full Text] [Related]
10. Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS. Clin Cancer Res; 2007 Jul 15; 13(14):4051-60. PubMed ID: 17634529 [Abstract] [Full Text] [Related]
11. Urokinase-induced smooth muscle cell responses require distinct signaling pathways: a role for the epidermal growth factor receptor. Nicholl SM, Roztocil E, Davies MG. J Vasc Surg; 2005 Apr 15; 41(4):672-81. PubMed ID: 15874933 [Abstract] [Full Text] [Related]
14. uPAR regulates pericellular proteolysis through a mechanism involving integrins and fMLF-receptors. Montuori N, Cosimato V, Rinaldi L, Rea VE, Alfano D, Ragno P. Thromb Haemost; 2013 Feb 15; 109(2):309-18. PubMed ID: 23238745 [Abstract] [Full Text] [Related]
16. uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma. Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS. PLoS One; 2011 Feb 11; 6(2):e17123. PubMed ID: 21347260 [Abstract] [Full Text] [Related]
17. Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells. Gupta R, Chetty C, Bhoopathi P, Lakka S, Mohanam S, Rao JS, Dinh DE. Int J Oncol; 2011 Mar 11; 38(3):733-44. PubMed ID: 21181094 [Abstract] [Full Text] [Related]
18. Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice. Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM. Cancer Res; 2005 Sep 01; 65(17):7775-81. PubMed ID: 16140945 [Abstract] [Full Text] [Related]
19. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC, Gujrati M, Rao JS. Oncogene; 2003 Sep 04; 22(38):5967-75. PubMed ID: 12955075 [Abstract] [Full Text] [Related]
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