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677 related items for PubMed ID: 18952447

  • 1. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Ogiyama T, Yokoyama K, Momose K, Katayama N, Orita M, Yamaguchi T, Furutani M, Hamada N, Takeuchi M, Okada M, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Dec 01; 16(23):10001-12. PubMed ID: 18952447
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.
    Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 May 15; 16(10):5452-64. PubMed ID: 18434170
    [Abstract] [Full Text] [Related]

  • 3. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
    [Abstract] [Full Text] [Related]

  • 4. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
    [Abstract] [Full Text] [Related]

  • 5. The effect of glucose on the potency of two distinct glycogen phosphorylase inhibitors.
    Andersen B, Westergaard N.
    Biochem J; 2002 Oct 15; 367(Pt 2):443-50. PubMed ID: 12099891
    [Abstract] [Full Text] [Related]

  • 6. Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.
    Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL.
    J Med Chem; 1998 Jul 30; 41(16):2934-8. PubMed ID: 9685232
    [No Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
    Dudash J, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4790-3. PubMed ID: 16143521
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases.
    Zhang L, Chen J, Gong Y, Liu J, Zhang L, Hua W, Sun H.
    Chem Biodivers; 2009 Jun 01; 6(6):864-74. PubMed ID: 19551727
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
    Miao GX, Wang YD, Yan ZW, Zhang LY.
    Bioorg Med Chem Lett; 2020 Jul 15; 30(14):127117. PubMed ID: 32527535
    [Abstract] [Full Text] [Related]

  • 10. Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819 ([R-R*,S*]-5-chloro-N-[2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide).
    Suh SW, Bergher JP, Anderson CM, Treadway JL, Fosgerau K, Swanson RA.
    J Pharmacol Exp Ther; 2007 Apr 15; 321(1):45-50. PubMed ID: 17251391
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory mode of indole-2-carboxamide derivatives against HLGPa: molecular docking and 3D-QSAR analyses.
    Liu G, Zhang Z, Luo X, Shen J, Liu H, Shen X, Chen K, Jiang H.
    Bioorg Med Chem; 2004 Aug 01; 12(15):4147-57. PubMed ID: 15246091
    [Abstract] [Full Text] [Related]

  • 12. Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase.
    Zhang L, Li H, Zhu Q, Liu J, Chen L, Leng Y, Jiang H, Liu H.
    Bioorg Med Chem; 2009 Oct 15; 17(20):7301-12. PubMed ID: 19758809
    [Abstract] [Full Text] [Related]

  • 13. Discovery of potent and orally active 3-alkoxy-5-phenoxy-N-thiazolyl benzamides as novel allosteric glucokinase activators.
    Iino T, Tsukahara D, Kamata K, Sasaki K, Ohyama S, Hosaka H, Hasegawa T, Chiba M, Nagata Y, Eiki J, Nishimura T.
    Bioorg Med Chem; 2009 Apr 01; 17(7):2733-43. PubMed ID: 19282189
    [Abstract] [Full Text] [Related]

  • 14. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D.
    Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758
    [Abstract] [Full Text] [Related]

  • 15. N-(4-{[4-(1H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors.
    Xu YJ, Miao HQ, Pan W, Navarro EC, Tonra JR, Mitelman S, Camara MM, Deevi DS, Kiselyov AS, Kussie P, Wong WC, Liu H.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):404-8. PubMed ID: 16246551
    [Abstract] [Full Text] [Related]

  • 16. Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Zhu P, Bi Y, Xu J, Li Z, Liu J, Zhang L, Ye W, Wu X.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6966-9. PubMed ID: 19889536
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Yonetoku Y, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Sep 15; 16(18):8627-34. PubMed ID: 18723356
    [Abstract] [Full Text] [Related]

  • 18. Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.
    Da Settimo F, Primofiore G, Da Settimo A, La Motta C, Simorini F, Novellino E, Greco G, Lavecchia A, Boldrini E.
    J Med Chem; 2003 Apr 10; 46(8):1419-28. PubMed ID: 12672241
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and glycogen phosphorylase inhibitor activity of functionalized 1,4-benzodioxanes.
    Czakó Z, Docsa T, Gergely P, Juhász L, Antus S.
    Pharmazie; 2010 Apr 10; 65(4):235-8. PubMed ID: 20432616
    [Abstract] [Full Text] [Related]

  • 20. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 10; 9(4):379-95. PubMed ID: 18393105
    [Abstract] [Full Text] [Related]

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