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Journal Abstract Search

677 related items for PubMed ID: 18952447

  • 21. Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N₁-arylsulfonyl indole derivatives as 5-HT₆ receptor ligands.
    Nirogi RV, Badange R, Kambhampati R, Chindhe A, Deshpande AD, Tiriveedhi V, Kandikere V, Muddana N, Abraham R, Khagga M.
    Bioorg Med Chem Lett; 2012 Dec 15; 22(24):7431-5. PubMed ID: 23141912
    [Abstract] [Full Text] [Related]

  • 22. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool.
    Shimamura K, Kitazawa H, Miyamoto Y, Kanesaka M, Nagumo A, Yoshimoto R, Aragane K, Morita N, Ohe T, Takahashi T, Nagase T, Sato N, Tokita S.
    J Pharmacol Exp Ther; 2009 Jul 15; 330(1):249-56. PubMed ID: 19359527
    [Abstract] [Full Text] [Related]

  • 23. Diverse effects of two allosteric inhibitors on the phosphorylation state of glycogen phosphorylase in hepatocytes.
    Latsis T, Andersen B, Agius L.
    Biochem J; 2002 Nov 15; 368(Pt 1):309-16. PubMed ID: 12186629
    [Abstract] [Full Text] [Related]

  • 24. Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Chen J, Liu J, Zhang L, Wu G, Hua W, Wu X, Sun H.
    Bioorg Med Chem Lett; 2006 Jun 01; 16(11):2915-9. PubMed ID: 16546381
    [Abstract] [Full Text] [Related]

  • 25. Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation.
    Uto Y, Ogata T, Kiyotsuka Y, Miyazawa Y, Ueno Y, Kurata H, Deguchi T, Yamada M, Watanabe N, Takagi T, Wakimoto S, Okuyama R, Konishi M, Kurikawa N, Kono K, Osumi J.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4159-66. PubMed ID: 19541482
    [Abstract] [Full Text] [Related]

  • 26. Pentacyclic triterpenes. Part 5: synthesis and SAR study of corosolic acid derivatives as inhibitors of glycogen phosphorylases.
    Wen X, Xia J, Cheng K, Zhang L, Zhang P, Liu J, Zhang L, Ni P, Sun H.
    Bioorg Med Chem Lett; 2007 Nov 01; 17(21):5777-82. PubMed ID: 17869102
    [Abstract] [Full Text] [Related]

  • 27. Stereoselective synthesis of bioactive isosteviol derivatives as alpha-glucosidase inhibitors.
    Wu Y, Yang JH, Dai GF, Liu CJ, Tian GQ, Ma WY, Tao JC.
    Bioorg Med Chem; 2009 Feb 15; 17(4):1464-73. PubMed ID: 19167896
    [Abstract] [Full Text] [Related]

  • 28. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.
    Yano S, Kazuno H, Suzuki N, Emura T, Wierzba K, Yamashita J, Tada Y, Yamada Y, Fukushima M, Asao T.
    Bioorg Med Chem; 2004 Jul 01; 12(13):3431-41. PubMed ID: 15186829
    [Abstract] [Full Text] [Related]

  • 29. Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads.
    Habash M, Taha MO.
    Bioorg Med Chem; 2011 Aug 15; 19(16):4746-71. PubMed ID: 21788139
    [Abstract] [Full Text] [Related]

  • 30. Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase.
    Kato A, Nasu N, Takebayashi K, Adachi I, Minami Y, Sanae F, Asano N, Watson AA, Nash RJ.
    J Agric Food Chem; 2008 Jun 25; 56(12):4469-73. PubMed ID: 18494482
    [Abstract] [Full Text] [Related]

  • 31. 1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
    Renton P, Speed J, Maddaford S, Annedi SC, Ramnauth J, Rakhit S, Andrews J.
    Bioorg Med Chem Lett; 2011 Sep 15; 21(18):5301-4. PubMed ID: 21813276
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.
    Takahashi T, Nagase T, Sasaki T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, Sato N.
    J Med Chem; 2009 May 28; 52(10):3142-5. PubMed ID: 19388647
    [Abstract] [Full Text] [Related]

  • 33. Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
    Schirok H, Kast R, Figueroa-Pérez S, Bennabi S, Gnoth MJ, Feurer A, Heckroth H, Thutewohl M, Paulsen H, Knorr A, Hütter J, Lobell M, Münter K, Geiss V, Ehmke H, Lang D, Radtke M, Mittendorf J, Stasch JP.
    ChemMedChem; 2008 Dec 28; 3(12):1893-904. PubMed ID: 18973168
    [Abstract] [Full Text] [Related]

  • 34. Discovery and evaluation of novel benzazepinone derivatives as glycogen phosphorylase inhibitors with potent activity.
    Wang Y, Yan Z, Guo Y, Zhang L.
    Future Med Chem; 2021 May 28; 13(10):897-909. PubMed ID: 33906369
    [Abstract] [Full Text] [Related]

  • 35. Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: potent and selective aromatase inhibitors.
    Lézé MP, Le Borgne M, Pinson P, Palusczak A, Duflos M, Le Baut G, Hartmann RW.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1134-7. PubMed ID: 16380254
    [Abstract] [Full Text] [Related]

  • 36. Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.
    Yao CH, Song JS, Chen CT, Yeh TK, Hung MS, Chang CC, Liu YW, Yuan MC, Hsieh CJ, Huang CY, Wang MH, Chiu CH, Hsieh TC, Wu SH, Hsiao WC, Chu KF, Tsai CH, Chao YS, Lee JC.
    J Med Chem; 2011 Jan 13; 54(1):166-78. PubMed ID: 21128592
    [Abstract] [Full Text] [Related]

  • 37. Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus.
    Park K, Lee BM, Hyun KH, Lee DH, Choi HH, Kim H, Chong W, Kim KB, Nam SY.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2280-93. PubMed ID: 24588963
    [Abstract] [Full Text] [Related]

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  • 40. Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes.
    Xu Q, Huang L, Liu J, Ma L, Chen T, Chen J, Peng F, Cao D, Yang Z, Qiu N, Qiu J, Wang G, Liang X, Peng A, Xiang M, Wei Y, Chen L.
    Eur J Med Chem; 2012 Jun 01; 52():70-81. PubMed ID: 22483089
    [Abstract] [Full Text] [Related]

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