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147 related items for PubMed ID: 18954039

  • 1. Antithyroid drug carbimazole and its analogues: synthesis and inhibition of peroxidase-catalyzed iodination of L-tyrosine.
    Das D, Roy G, Mugesh G.
    J Med Chem; 2008 Nov 27; 51(22):7313-7. PubMed ID: 18954039
    [Abstract] [Full Text] [Related]

  • 2. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action.
    Manna D, Roy G, Mugesh G.
    Acc Chem Res; 2013 Nov 19; 46(11):2706-15. PubMed ID: 23883148
    [Abstract] [Full Text] [Related]

  • 3. Anti-thyroid drugs and thyroid hormone synthesis: effect of methimazole derivatives on peroxidase-catalyzed reactions.
    Roy G, Mugesh G.
    J Am Chem Soc; 2005 Nov 02; 127(43):15207-17. PubMed ID: 16248663
    [Abstract] [Full Text] [Related]

  • 4. Antithyroid drugs and their analogues protect against peroxynitrite-mediated protein tyrosine nitration--a mechanistic study.
    Bhabak KP, Mugesh G.
    Chemistry; 2010 Jan 25; 16(4):1175-85. PubMed ID: 20029917
    [Abstract] [Full Text] [Related]

  • 5. Interaction of methimazole with I2: X-ray crystal structure of the charge transfer complex methimazole-I2. implications for the mechanism of action of methimazole-based antithyroid drugs.
    Isaia F, Aragoni MC, Arca M, Demartin F, Devillanova FA, Floris G, Garau A, Hursthouse MB, Lippolis V, Medda R, Oppo F, Pira M, Verani G.
    J Med Chem; 2008 Jul 10; 51(13):4050-3. PubMed ID: 18529045
    [Abstract] [Full Text] [Related]

  • 6. Biomimetic studies on anti-thyroid drugs and thyroid hormone synthesis.
    Roy G, Nethaji M, Mugesh G.
    J Am Chem Soc; 2004 Mar 10; 126(9):2712-3. PubMed ID: 14995183
    [Abstract] [Full Text] [Related]

  • 7. Selenium analogues of antithyroid drugs--recent developments.
    Roy G, Mugesh G.
    Chem Biodivers; 2008 Mar 10; 5(3):414-39. PubMed ID: 18357551
    [Abstract] [Full Text] [Related]

  • 8. Reactions of 1-methyl-2-mercaptoimidazole with hypochlorous acid and superoxide.
    Nakamura M, Shishido N, Akutsu H.
    Jpn J Infect Dis; 2004 Oct 10; 57(5):S34-5. PubMed ID: 15507768
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and antithyroid activity of 1,4,5-trialkyl 2-thioimidazole derivatives.
    Fatimi J, Lagorce JF, Chabernaud ML, Comby F, Buxeraud J, Raby C.
    Farmaco; 1994 Apr 10; 49(4):253-7. PubMed ID: 7519428
    [Abstract] [Full Text] [Related]

  • 10. Rapid conversion of carbimazole to methimazole in serum; evidence for an enzymatic mechanism.
    Nakashima T, Taurog A.
    Clin Endocrinol (Oxf); 1979 Jun 10; 10(6):637-48. PubMed ID: 476986
    [Abstract] [Full Text] [Related]

  • 11. Interaction of anti-thyroid drugs with iodine: the isolation of two unusual ionic compounds derived from Se-methimazole.
    Roy G, Nethaji M, Mugesh G.
    Org Biomol Chem; 2006 Aug 07; 4(15):2883-7. PubMed ID: 16855736
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of peroxynitrite- and peroxidase-mediated protein tyrosine nitration by imidazole-based thiourea and selenourea derivatives.
    Bhabak KP, Satheeshkumar K, Jayavelu S, Mugesh G.
    Org Biomol Chem; 2011 Nov 07; 9(21):7343-50. PubMed ID: 21894311
    [Abstract] [Full Text] [Related]

  • 13. [Carbimazole, synthetic antithyroid drug].
    Taéron C.
    Rev Infirm; 2007 Apr 07; (129):41-2. PubMed ID: 17500290
    [No Abstract] [Full Text] [Related]

  • 14. Inhibition of lactoperoxidase-catalyzed oxidation by imidazole-based thiones and selones: a mechanistic study.
    Roy G, Jayaram PN, Mugesh G.
    Chem Asian J; 2013 Aug 07; 8(8):1910-21. PubMed ID: 23737077
    [Abstract] [Full Text] [Related]

  • 15. [Metabolism of thioureylene antithyroid drugs--particularly with relationship between intrathyroidal metabolism of the drugs and the mechanisms of action (author's transl)].
    Nakashima T.
    Rinsho Byori; 1982 Feb 07; 30(2):170-8. PubMed ID: 6177885
    [No Abstract] [Full Text] [Related]

  • 16. Synthesis and structures of Se analogues of the antithyroid drug 6-n-propyl-2-thiouracil and its alkyl derivatives: formation of dimeric Se-Se compounds and deselenation reactions of charge-transfer adducts of diiodine.
    Antoniadis CD, Hadjikakou SK, Hadjiliadis N, Papakyriakou A, Baril M, Butler IS.
    Chemistry; 2006 Sep 06; 12(26):6888-97. PubMed ID: 16773663
    [Abstract] [Full Text] [Related]

  • 17. Carbimazole is an inhibitor of protein synthesis and protects from neuronal hypoxic damage in vitro.
    Lehane C, Guelzow T, Zenker S, Erxleben A, Schwer CI, Heimrich B, Buerkle H, Humar M.
    J Pharmacol Exp Ther; 2013 Dec 06; 347(3):781-93. PubMed ID: 24049063
    [Abstract] [Full Text] [Related]

  • 18. Heme peroxidase-catalyzed iodination of human angiotensins and the effect of iodination on angiotensin converting enzyme activity.
    Bhuyan BJ, Mugesh G.
    Inorg Chem; 2008 Aug 04; 47(15):6569-71. PubMed ID: 18598023
    [Abstract] [Full Text] [Related]

  • 19. Structure-based design, synthesis, and pharmacological evaluation of 3-(aminoalkyl)-5-fluoroindoles as myeloperoxidase inhibitors.
    Soubhye J, Prévost M, Van Antwerpen P, Zouaoui Boudjeltia K, Rousseau A, Furtmüller PG, Obinger C, Vanhaeverbeek M, Ducobu J, Néve J, Gelbcke M, Dufrasne FO.
    J Med Chem; 2010 Dec 23; 53(24):8747-59. PubMed ID: 21090682
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and structure-activity relationships of a class of sodium iodide symporter function inhibitors.
    Waltz F, Pillette L, Verhaeghe E, Ambroise Y.
    ChemMedChem; 2011 Oct 04; 6(10):1775-7. PubMed ID: 21751403
    [No Abstract] [Full Text] [Related]

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