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89 related items for PubMed ID: 18954531

  • 1. Bioactivity, pharmacokinetics, and immunogenicity assays in preclinical and clinical trials for recombinant human endostatin.
    Hu B, Zhu HW, Zhu LP, Li C, Rong ZG, Xu JM, Wu ZW, Wang JJ, Xu GX.
    Acta Pharmacol Sin; 2008 Nov; 29(11):1357-69. PubMed ID: 18954531
    [Abstract] [Full Text] [Related]

  • 2. Phase I clinical trial of recombinant human endostatin administered as a short intravenous infusion repeated daily.
    Eder JP, Supko JG, Clark JW, Puchalski TA, Garcia-Carbonero R, Ryan DP, Shulman LN, Proper J, Kirvan M, Rattner B, Connors S, Keogan MT, Janicek MJ, Fogler WE, Schnipper L, Kinchla N, Sidor C, Phillips E, Folkman J, Kufe DW.
    J Clin Oncol; 2002 Sep 15; 20(18):3772-84. PubMed ID: 12228197
    [Abstract] [Full Text] [Related]

  • 3. [Studies on antitumor activity of rhEndostatin].
    Li HY, Li Y, Liu ZH, Wu HJ, Chen FH, Chen XG.
    Yao Xue Xue Bao; 2002 Oct 15; 37(10):763-6. PubMed ID: 12567857
    [Abstract] [Full Text] [Related]

  • 4. Pharmacokinetics of His-tag recombinant human endostatin in Rhesus monkeys.
    Song HF, Liu XW, Zhang HN, Zhu BZ, Yuan SJ, Liu SY, Tang ZM.
    Acta Pharmacol Sin; 2005 Jan 15; 26(1):124-8. PubMed ID: 15659125
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic efficacy of recombinant human endostatin combined with chemotherapeutics in mice-transplanted tumors.
    Zhu LP, Xing J, Wang QX, Kou L, Li C, Hu B, Wu ZW, Wang JJ, Xu GX.
    Eur J Pharmacol; 2009 Sep 01; 617(1-3):23-7. PubMed ID: 19615993
    [Abstract] [Full Text] [Related]

  • 6. Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors.
    Kulke MH, Bergsland EK, Ryan DP, Enzinger PC, Lynch TJ, Zhu AX, Meyerhardt JA, Heymach JV, Fogler WE, Sidor C, Michelini A, Kinsella K, Venook AP, Fuchs CS.
    J Clin Oncol; 2006 Aug 01; 24(22):3555-61. PubMed ID: 16877721
    [Abstract] [Full Text] [Related]

  • 7. The methods for determining the purity and in vitro or in vivo activity of recombinant human endostatin.
    Zhang HY, Han QW, Xu YF, Fan YR, Dai QM, Xu JM, Zhu HW, Rong ZG, Wang JJ, Xu GX.
    Cancer Biol Ther; 2005 Feb 01; 4(2):207-12. PubMed ID: 15753663
    [Abstract] [Full Text] [Related]

  • 8. Synergistic activity of recombinant human endostatin in combination with adriamycin: analysis of in vitro activity on endothelial cells and in vivo tumor progression in an orthotopic murine mammary carcinoma model.
    Plum SM, Hanson AD, Volker KM, Vu HA, Sim BK, Fogler WE, Fortier AH.
    Clin Cancer Res; 2003 Oct 01; 9(12):4619-26. PubMed ID: 14555538
    [Abstract] [Full Text] [Related]

  • 9. Anti-tumor effect of a novel soluble recombinant human endostatin: administered as a single agent or in combination with chemotherapy agents in mouse tumor models.
    Ren Z, Wang Y, Jiang W, Dai W, Jiang Y.
    PLoS One; 2014 Oct 01; 9(9):e107823. PubMed ID: 25229620
    [Abstract] [Full Text] [Related]

  • 10. A quantitative method for measuring the antitumor potency of recombinant human endostatin in vivo.
    Xu YF, Zhu LP, Hu B, Rong ZG, Zhu HW, Xu JM, Wu ZW, Wang JJ, Xu GX.
    Eur J Pharmacol; 2007 Jun 14; 564(1-3):1-6. PubMed ID: 17346697
    [Abstract] [Full Text] [Related]

  • 11. Optimizing drug delivery for enhancing therapeutic efficacy of recombinant human endostatin in cancer treatment.
    Xu F, Ma Q, Sha H.
    Crit Rev Ther Drug Carrier Syst; 2007 Jun 14; 24(5):445-92. PubMed ID: 18197781
    [Abstract] [Full Text] [Related]

  • 12. Expression of soluble, biologically active recombinant human endostatin in Escherichia coli.
    Xu HM, Zhang GY, Ji XD, Cao L, Shu L, Hua ZC.
    Protein Expr Purif; 2005 Jun 14; 41(2):252-8. PubMed ID: 15866710
    [Abstract] [Full Text] [Related]

  • 13. Effects of recombinant human endostatin on a human neuroblastoma xenograft.
    Kuroiwa M, Ikeda H, Hongo T, Tsuchida Y, Hirato J, Kaneko Y, Suzuki N, Obana K, Makino SI.
    Int J Mol Med; 2001 Oct 14; 8(4):391-6. PubMed ID: 11562777
    [Abstract] [Full Text] [Related]

  • 14. Inhibitory effect of recombinant human endostatin on the proliferation of hypertrophic scar fibroblasts in a rabbit ear model.
    Gong YF, Zhang XM, Liu F, Wang ZZ, Deng XF, Jiao Y, Li XJ, Huang XY.
    Eur J Pharmacol; 2016 Nov 15; 791():647-654. PubMed ID: 27693124
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics of PEGylated recombinant human endostatin in rhesus monkeys.
    Guo L, Li Z, Xu B, Yu M, Fu Y, Liu L, Wang J, Luo Y.
    Life Sci; 2019 Dec 01; 238():116967. PubMed ID: 31626794
    [Abstract] [Full Text] [Related]

  • 16. Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys.
    Guo L, Geng X, Chen Y, Qi F, Liu L, Miao Y, Lin Z, Yu M, Li Z, Fu Y, Li B, Luo Y.
    Regul Toxicol Pharmacol; 2014 Aug 01; 69(3):512-23. PubMed ID: 24878240
    [Abstract] [Full Text] [Related]

  • 17. Anti-proliferative effect of recombinant human endostatin on synovial fibroblasts in rats with adjuvant arthritis.
    Huang XY, Zhang XM, Chen FH, Zhou LL, Deng XF, Liu YJ, Li XJ.
    Eur J Pharmacol; 2014 Jan 15; 723():7-14. PubMed ID: 24239715
    [Abstract] [Full Text] [Related]

  • 18. Tolerance and Pharmacokinetics of Recombinant Human Endostatin Administered as Single-Dose or Multiple-Dose Infusions in Patients With Advanced Solid Tumors: A Phase I Clinical Trial.
    Wang X, Shi Y, Jia Y, Zhao W, Zhang L, Bai G, Ren Y, Chen YZ, Tong Z.
    Technol Cancer Res Treat; 2021 Jan 15; 20():15330338211064434. PubMed ID: 34931914
    [Abstract] [Full Text] [Related]

  • 19. Effect of recombinant human endostatin on hypertrophic scar fibroblast apoptosis in a rabbit ear model.
    Gong YF, Zhang XM, Yu J, Huang TY, Wang ZZ, Liu F, Huang XY.
    Biomed Pharmacother; 2017 Jul 15; 91():680-686. PubMed ID: 28499239
    [Abstract] [Full Text] [Related]

  • 20. Continuous versus intermittent administration of human endostatin in xenografted human neuroblastoma.
    Kuroiwa M, Takeuchi T, Lee JH, Yoshizawa J, Hirato J, Kaneko S, Choi SH, Suzuki N, Ikeda H, Tsuchida Y.
    J Pediatr Surg; 2003 Oct 15; 38(10):1499-505. PubMed ID: 14577075
    [Abstract] [Full Text] [Related]


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