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406 related items for PubMed ID: 18973804

  • 1. Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.
    Chowdhury I, Mo Y, Gao L, Kazi A, Fisher AB, Feinstein SI.
    Free Radic Biol Med; 2009 Jan 15; 46(2):146-53. PubMed ID: 18973804
    [Abstract] [Full Text] [Related]

  • 2. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.
    Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohé R, Kensler TW, Yamamoto M, Biswal S.
    Am J Respir Cell Mol Biol; 2006 Dec 15; 35(6):639-50. PubMed ID: 16794261
    [Abstract] [Full Text] [Related]

  • 3. Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress.
    Kubo E, Chhunchha B, Singh P, Sasaki H, Singh DP.
    Sci Rep; 2017 Oct 26; 7(1):14130. PubMed ID: 29074861
    [Abstract] [Full Text] [Related]

  • 4. Keratinocyte growth factor and glucocorticoid induction of human peroxiredoxin 6 gene expression occur by independent mechanisms that are synergistic.
    Chowdhury I, Fisher AB, Christofidou-Solomidou M, Gao L, Tao JQ, Sorokina EM, Lien YC, Bates SR, Feinstein SI.
    Antioxid Redox Signal; 2014 Jan 20; 20(3):391-402. PubMed ID: 23815338
    [Abstract] [Full Text] [Related]

  • 5. Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements.
    Arinze IJ, Kawai Y.
    J Biol Chem; 2005 Mar 18; 280(11):9786-95. PubMed ID: 15640523
    [Abstract] [Full Text] [Related]

  • 6. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
    Habib E, Linher-Melville K, Lin HX, Singh G.
    Redox Biol; 2015 Aug 18; 5():33-42. PubMed ID: 25827424
    [Abstract] [Full Text] [Related]

  • 7. Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
    Sankaranarayanan K, Jaiswal AK.
    J Biol Chem; 2004 Dec 03; 279(49):50810-7. PubMed ID: 15385560
    [Abstract] [Full Text] [Related]

  • 8. Long-acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway.
    Koriyama Y, Chiba K, Yamazaki M, Suzuki H, Muramoto K, Kato S.
    J Neurochem; 2010 Oct 03; 115(1):79-91. PubMed ID: 20681953
    [Abstract] [Full Text] [Related]

  • 9. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z, Zhang S, Chan JY, Zhang DD.
    Mol Cell Biol; 2007 Sep 03; 27(18):6334-49. PubMed ID: 17636022
    [Abstract] [Full Text] [Related]

  • 10. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
    Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.
    Toxicol Appl Pharmacol; 2010 Apr 01; 244(1):27-36. PubMed ID: 20026152
    [Abstract] [Full Text] [Related]

  • 11. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin.
    Tanigawa S, Fujii M, Hou DX.
    Free Radic Biol Med; 2007 Jun 01; 42(11):1690-703. PubMed ID: 17462537
    [Abstract] [Full Text] [Related]

  • 12. Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.
    Yao JW, Liu J, Kong XZ, Zhang SG, Wang XH, Yu M, Zhan YQ, Li W, Xu WX, Tang LJ, Ge CH, Wang L, Li CY, Yang XM.
    Toxicol Appl Pharmacol; 2012 Mar 01; 259(2):227-35. PubMed ID: 22245129
    [Abstract] [Full Text] [Related]

  • 13. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.
    Dhakshinamoorthy S, Jain AK, Bloom DA, Jaiswal AK.
    J Biol Chem; 2005 Apr 29; 280(17):16891-900. PubMed ID: 15734732
    [Abstract] [Full Text] [Related]

  • 14. Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
    Itoh K, Mimura J, Yamamoto M.
    Antioxid Redox Signal; 2010 Dec 01; 13(11):1665-78. PubMed ID: 20446768
    [Abstract] [Full Text] [Related]

  • 15. Identification of aldo-keto reductases as NRF2-target marker genes in human cells.
    Jung KA, Choi BH, Nam CW, Song M, Kim ST, Lee JY, Kwak MK.
    Toxicol Lett; 2013 Mar 27; 218(1):39-49. PubMed ID: 23305850
    [Abstract] [Full Text] [Related]

  • 16. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model.
    Shimozono R, Asaoka Y, Yoshizawa Y, Aoki T, Noda H, Yamada M, Kaino M, Mochizuki H.
    Mol Pharmacol; 2013 Jul 27; 84(1):62-70. PubMed ID: 23592516
    [Abstract] [Full Text] [Related]

  • 17. Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.
    Kaspar JW, Jaiswal AK.
    J Biol Chem; 2010 Jan 01; 285(1):153-62. PubMed ID: 19897490
    [Abstract] [Full Text] [Related]

  • 18. Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage.
    Cao TT, Ma L, Kandpal G, Warren L, Hess JF, Seabrook GR.
    J Neurochem; 2005 Oct 01; 95(2):406-17. PubMed ID: 16092930
    [Abstract] [Full Text] [Related]

  • 19. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.
    Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S.
    Am J Respir Cell Mol Biol; 2010 May 01; 42(5):524-36. PubMed ID: 19520915
    [Abstract] [Full Text] [Related]

  • 20. Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.
    Kim YJ, Ahn JY, Liang P, Ip C, Zhang Y, Park YM.
    Cancer Res; 2007 Jan 15; 67(2):546-54. PubMed ID: 17234762
    [Abstract] [Full Text] [Related]

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