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Journal Abstract Search

266 related items for PubMed ID: 18974130

  • 1. Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.
    Anand P, Kunnumakkara AB, Harikumar KB, Ahn KS, Badmaev V, Aggarwal BB.
    Cancer Res; 2008 Nov 01; 68(21):8861-70. PubMed ID: 18974130
    [Abstract] [Full Text] [Related]

  • 2. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y, Singh S, Aggarwal BB.
    J Biol Chem; 2004 Apr 09; 279(15):15096-104. PubMed ID: 14711835
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  • 3. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
    Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB.
    J Biol Chem; 2006 Jun 23; 281(25):17023-17033. PubMed ID: 16624823
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  • 4. Bharangin, a diterpenoid quinonemethide, abolishes constitutive and inducible nuclear factor-κB (NF-κB) activation by modifying p65 on cysteine 38 residue and reducing inhibitor of nuclear factor-κB α kinase activation, leading to suppression of NF-κB-regulated gene expression and sensitization of tumor cells to chemotherapeutic agents.
    Gupta SC, Kannappan R, Kim J, Rahman GM, Francis SK, Raveendran R, Nair MS, Das J, Aggarwal BB.
    Mol Pharmacol; 2011 Nov 23; 80(5):769-81. PubMed ID: 21795584
    [Abstract] [Full Text] [Related]

  • 5. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 23; 69(1):195-206. PubMed ID: 16219905
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  • 6. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H, Takada Y, Murakami A, Aggarwal BB.
    J Immunol; 2005 Jun 01; 174(11):7383-92. PubMed ID: 15905586
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  • 11. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S, Majumdar S, Banerjee S, Aggarwal BB.
    Cancer Res; 2003 Aug 01; 63(15):4375-83. PubMed ID: 12907607
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  • 12. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.
    Takada Y, Gillenwater A, Ichikawa H, Aggarwal BB.
    J Biol Chem; 2006 Mar 03; 281(9):5612-22. PubMed ID: 16377638
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  • 13. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y, Murakami A, Aggarwal BB.
    Oncogene; 2005 Oct 20; 24(46):6957-69. PubMed ID: 16007145
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  • 14. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
    Ahn KS, Sethi G, Krishnan K, Aggarwal BB.
    J Biol Chem; 2007 Jan 05; 282(1):809-20. PubMed ID: 17114179
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  • 15. Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expression.
    Ichikawa H, Nair MS, Takada Y, Sheeja DB, Kumar MA, Oommen OV, Aggarwal BB.
    Clin Cancer Res; 2006 Oct 01; 12(19):5910-8. PubMed ID: 17021000
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  • 16. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 01; 7(6):1604-14. PubMed ID: 18566231
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  • 17. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
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  • 19. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.
    J Biol Chem; 2012 Jan 02; 287(1):245-256. PubMed ID: 22065587
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  • 20. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
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