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Journal Abstract Search

576 related items for PubMed ID: 18976648

  • 1. Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y5 receptor and development of a novel Y5-selective radioligand.
    Mullins D, Adham N, Hesk D, Wu Y, Kelly J, Huang Y, Guzzi M, Zhang X, McCombie S, Stamford A, Parker E.
    Eur J Pharmacol; 2008 Dec 28; 601(1-3):1-7. PubMed ID: 18976648
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  • 3. Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor.
    Kakui N, Tanaka J, Tabata Y, Asai K, Masuda N, Miyara T, Nakatani Y, Ohsawa F, Nishikawa N, Sugai M, Suzuki M, Aoki K, Kitaguchi H.
    J Pharmacol Exp Ther; 2006 May 28; 317(2):562-70. PubMed ID: 16436501
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  • 6. Characterization of a new neuropeptide Y Y5 agonist radioligand: [125I][cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34]hPP.
    Dumont Y, Thakur M, Beck-Sickinger A, Fournier A, Quirion R.
    Neuropeptides; 2004 Aug 28; 38(4):163-74. PubMed ID: 15337369
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  • 7. Design, synthesis, and biological evaluation of substituted 2-cyclohexyl-4-phenyl-1H-imidazoles: potent and selective neuropeptide Y Y5-receptor antagonists.
    Blum CA, Zheng X, De Lombaert S.
    J Med Chem; 2004 Apr 22; 47(9):2318-25. PubMed ID: 15084130
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  • 9. The novel neuropeptide Y Y(1) receptor antagonist J-104870: a potent feeding suppressant with oral bioavailability.
    Kanatani A, Kanno T, Ishihara A, Hata M, Sakuraba A, Tanaka T, Tsuchiya Y, Mase T, Fukuroda T, Fukami T, Ihara M.
    Biochem Biophys Res Commun; 1999 Dec 09; 266(1):88-91. PubMed ID: 10581170
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  • 10. Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.
    Bonaventure P, Nepomuceno D, Mazur C, Lord B, Rudolph DA, Jablonowski JA, Carruthers NI, Lovenberg TW.
    J Pharmacol Exp Ther; 2004 Mar 09; 308(3):1130-7. PubMed ID: 14617685
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  • 11. Synthesis and evaluation of new hydrazide derivatives as neuropeptide Y Y5 receptor antagonists for the treatment of obesity.
    Juanenea L, Galiano S, Erviti O, Moreno A, Pérez S, Aldana I, Monge A.
    Bioorg Med Chem; 2004 Sep 01; 12(17):4717-23. PubMed ID: 15358298
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  • 14. The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.
    Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA.
    J Pharmacol Exp Ther; 2009 Mar 01; 328(3):900-11. PubMed ID: 19098165
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  • 16. Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands.
    Ziemek R, Brennauer A, Schneider E, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A.
    Eur J Pharmacol; 2006 Dec 03; 551(1-3):10-8. PubMed ID: 17027743
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  • 17. Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor.
    Langmead CJ, Jerman JC, Brough SJ, Scott C, Porter RA, Herdon HJ.
    Br J Pharmacol; 2004 Jan 03; 141(2):340-6. PubMed ID: 14691055
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  • 20. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.
    Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L.
    J Pharmacol Exp Ther; 2009 Jul 03; 330(1):342-51. PubMed ID: 19401496
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