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875 related items for PubMed ID: 18978810

  • 1. Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy.
    García-Maceira P, Mateo J.
    Oncogene; 2009 Jan 22; 28(3):313-24. PubMed ID: 18978810
    [Abstract] [Full Text] [Related]

  • 2. YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
    Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM.
    Oncogene; 2007 Jun 07; 26(27):3941-51. PubMed ID: 17213816
    [Abstract] [Full Text] [Related]

  • 3. A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation.
    Jin X, Jin HR, Lee D, Lee JH, Kim SK, Lee JJ.
    Eur J Pharmacol; 2008 Sep 11; 592(1-3):41-7. PubMed ID: 18639543
    [Abstract] [Full Text] [Related]

  • 4. Liquiritigenin inhibits serum-induced HIF-1α and VEGF expression via the AKT/mTOR-p70S6K signalling pathway in HeLa cells.
    Xie SR, Wang Y, Liu CW, Luo K, Cai YQ.
    Phytother Res; 2012 Aug 11; 26(8):1133-41. PubMed ID: 22170854
    [Abstract] [Full Text] [Related]

  • 5. Silibinin inhibits expression of HIF-1alpha through suppression of protein translation in prostate cancer cells.
    Jung HJ, Park JW, Lee JS, Lee SR, Jang BC, Suh SI, Suh MH, Baek WK.
    Biochem Biophys Res Commun; 2009 Dec 04; 390(1):71-6. PubMed ID: 19778521
    [Abstract] [Full Text] [Related]

  • 6. trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
    Cao Z, Fang J, Xia C, Shi X, Jiang BH.
    Clin Cancer Res; 2004 Aug 01; 10(15):5253-63. PubMed ID: 15297429
    [Abstract] [Full Text] [Related]

  • 7. The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia.
    Li L, Qu Y, Mao M, Xiong Y, Mu D.
    Brain Res; 2008 Mar 04; 1197():152-8. PubMed ID: 18241842
    [Abstract] [Full Text] [Related]

  • 8. Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway.
    Jin HO, An S, Lee HC, Woo SH, Seo SK, Choe TB, Yoo DH, Lee SB, Um HD, Lee SJ, Park MJ, Kim JI, Hong SI, Rhee CH, Park IC.
    Cell Signal; 2007 Jul 04; 19(7):1393-403. PubMed ID: 17307335
    [Abstract] [Full Text] [Related]

  • 9. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
    Mi C, Ma J, Wang KS, Zuo HX, Wang Z, Li MY, Piao LX, Xu GH, Li X, Quan ZS, Jin X.
    J Ethnopharmacol; 2017 May 05; 203():27-38. PubMed ID: 28341244
    [Abstract] [Full Text] [Related]

  • 10. Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Simioni C, Leung E, Maclennan S, Baraldi PG, Borea PA.
    Mol Pharmacol; 2007 Aug 05; 72(2):395-406. PubMed ID: 17488804
    [Abstract] [Full Text] [Related]

  • 11. Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
    Wang Y, Zhao Q, Ma S, Yang F, Gong Y, Ke C.
    IUBMB Life; 2007 Nov 05; 59(11):717-21. PubMed ID: 17968710
    [Abstract] [Full Text] [Related]

  • 12. Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1alpha expression through activation of AKT and P70S6K1 in human ovarian cancer cells.
    Liu LZ, Hu XW, Xia C, He J, Zhou Q, Shi X, Fang J, Jiang BH.
    Free Radic Biol Med; 2006 Nov 15; 41(10):1521-33. PubMed ID: 17045920
    [Abstract] [Full Text] [Related]

  • 13. Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells.
    Tomita M, Semenza GL, Michiels C, Matsuda T, Uchihara JN, Okudaira T, Tanaka Y, Taira N, Ohshiro K, Mori N.
    Biochem J; 2007 Sep 01; 406(2):317-23. PubMed ID: 17576198
    [Abstract] [Full Text] [Related]

  • 14. Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
    Dayan F, Bilton RL, Laferrière J, Trottier E, Roux D, Pouyssegur J, Mazure NM.
    J Cell Physiol; 2009 Jan 01; 218(1):167-74. PubMed ID: 18781596
    [Abstract] [Full Text] [Related]

  • 15. Suppression of the proliferation of hypoxia-Induced retinal pigment epithelial cell by rapamycin through the /mTOR/HIF-1α/VEGF/ signaling.
    Liu NN, Zhao N, Cai N.
    IUBMB Life; 2015 Jun 01; 67(6):446-52. PubMed ID: 25988388
    [Abstract] [Full Text] [Related]

  • 16. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N, Nester RA, Sarkar MA.
    Toxicol Appl Pharmacol; 2004 Apr 01; 196(1):124-35. PubMed ID: 15050414
    [Abstract] [Full Text] [Related]

  • 17. 4′,6-dihydroxy-4-methoxyisoaurone inhibits the HIF-1α pathway through inhibition of Akt/mTOR/p70S6K/4E-BP1 phosphorylation.
    Mi C, Ma J, Shi H, Li J, Wang F, Lee JJ, Jin X.
    J Pharmacol Sci; 2014 Apr 01; 125(2):193-201. PubMed ID: 25075425
    [Abstract] [Full Text] [Related]

  • 18. Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.
    Ma J, Zi Jiang Y, Shi H, Mi C, Li J, Xing Nan J, Wu X, Joon Lee J, Jin X.
    Eur J Pharmacol; 2014 Jan 15; 723():46-54. PubMed ID: 24333213
    [Abstract] [Full Text] [Related]

  • 19. Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
    Liu L, Li F, Cardelli JA, Martin KA, Blenis J, Huang S.
    Oncogene; 2006 Nov 09; 25(53):7029-40. PubMed ID: 16715128
    [Abstract] [Full Text] [Related]

  • 20. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX, Yang X, Sreejayan N, Ren J.
    Exp Neurol; 2007 Jan 09; 203(1):196-204. PubMed ID: 16962100
    [Abstract] [Full Text] [Related]

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