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211 related items for PubMed ID: 18981174

  • 1. Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2.
    Edinger RS, Lebowitz J, Li H, Alzamora R, Wang H, Johnson JP, Hallows KR.
    J Biol Chem; 2009 Jan 02; 284(1):150-157. PubMed ID: 18981174
    [Abstract] [Full Text] [Related]

  • 2. AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.
    Bhalla V, Oyster NM, Fitch AC, Wijngaarden MA, Neumann D, Schlattner U, Pearce D, Hallows KR.
    J Biol Chem; 2006 Sep 08; 281(36):26159-69. PubMed ID: 16844684
    [Abstract] [Full Text] [Related]

  • 3. Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells.
    Flores SY, Loffing-Cueni D, Kamynina E, Daidié D, Gerbex C, Chabanel S, Dudler J, Loffing J, Staub O.
    J Am Soc Nephrol; 2005 Aug 08; 16(8):2279-87. PubMed ID: 15958725
    [Abstract] [Full Text] [Related]

  • 4. 14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.
    Ichimura T, Yamamura H, Sasamoto K, Tominaga Y, Taoka M, Kakiuchi K, Shinkawa T, Takahashi N, Shimada S, Isobe T.
    J Biol Chem; 2005 Apr 01; 280(13):13187-94. PubMed ID: 15677482
    [Abstract] [Full Text] [Related]

  • 5. Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.
    Chandran S, Li H, Dong W, Krasinska K, Adams C, Alexandrova L, Chien A, Hallows KR, Bhalla V.
    J Biol Chem; 2011 Oct 28; 286(43):37830-40. PubMed ID: 21900244
    [Abstract] [Full Text] [Related]

  • 6. A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes.
    Fouladkou F, Alikhani-Koopaei R, Vogt B, Flores SY, Malbert-Colas L, Lecomte MC, Loffing J, Frey FJ, Frey BM, Staub O.
    Am J Physiol Renal Physiol; 2004 Sep 28; 287(3):F550-61. PubMed ID: 15140763
    [Abstract] [Full Text] [Related]

  • 7. Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.
    Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O.
    J Am Soc Nephrol; 2011 Sep 28; 22(9):1707-19. PubMed ID: 21852580
    [Abstract] [Full Text] [Related]

  • 8. The phosphorylation site T613 in the β-subunit of rat epithelial Na+ channel (ENaC) modulates channel inhibition by Nedd4-2.
    Krueger B, Yang L, Korbmacher C, Rauh R.
    Pflugers Arch; 2018 Apr 28; 470(4):649-660. PubMed ID: 29397423
    [Abstract] [Full Text] [Related]

  • 9. COMMD1 downregulates the epithelial sodium channel through Nedd4-2.
    Ke Y, Butt AG, Swart M, Liu YF, McDonald FJ.
    Am J Physiol Renal Physiol; 2010 Jun 28; 298(6):F1445-56. PubMed ID: 20237237
    [Abstract] [Full Text] [Related]

  • 10. Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB.
    Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F.
    Obes Res; 2004 May 28; 12(5):862-70. PubMed ID: 15166308
    [Abstract] [Full Text] [Related]

  • 11. Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.
    Bhalla V, Daidié D, Li H, Pao AC, LaGrange LP, Wang J, Vandewalle A, Stockand JD, Staub O, Pearce D.
    Mol Endocrinol; 2005 Dec 28; 19(12):3073-84. PubMed ID: 16099816
    [Abstract] [Full Text] [Related]

  • 12. Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2.
    Lee IH, Dinudom A, Sanchez-Perez A, Kumar S, Cook DI.
    J Biol Chem; 2007 Oct 12; 282(41):29866-73. PubMed ID: 17715136
    [Abstract] [Full Text] [Related]

  • 13. The phosphorylation of endogenous Nedd4-2 In Na(+)-absorbing human airway epithelial cells.
    Ismail NA, Baines DL, Wilson SM.
    Eur J Pharmacol; 2014 Jun 05; 732(100):32-42. PubMed ID: 24657276
    [Abstract] [Full Text] [Related]

  • 14. β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells.
    Ho PY, Li H, Pavlov TS, Tuerk RD, Tabares D, Brunisholz R, Neumann D, Staruschenko A, Hallows KR.
    J Biol Chem; 2018 Jul 20; 293(29):11612-11624. PubMed ID: 29858246
    [Abstract] [Full Text] [Related]

  • 15. Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
    Al-Qusairi L, Basquin D, Roy A, Stifanelli M, Rajaram RD, Debonneville A, Nita I, Maillard M, Loffing J, Subramanya AR, Staub O.
    Am J Physiol Renal Physiol; 2016 Aug 01; 311(2):F330-42. PubMed ID: 27009335
    [Abstract] [Full Text] [Related]

  • 16. An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel.
    Liang X, Butterworth MB, Peters KW, Walker WH, Frizzell RA.
    J Biol Chem; 2008 Oct 10; 283(41):27418-27425. PubMed ID: 18687683
    [Abstract] [Full Text] [Related]

  • 17. Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel.
    Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D.
    J Biol Chem; 2010 Jul 09; 285(28):21671-8. PubMed ID: 20466724
    [Abstract] [Full Text] [Related]

  • 18. (Pro)renin receptor contributes to regulation of renal epithelial sodium channel.
    Quadri S, Siragy HM.
    J Hypertens; 2016 Mar 09; 34(3):486-94; discussion 494. PubMed ID: 26771338
    [Abstract] [Full Text] [Related]

  • 19. Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression.
    Debonneville C, Flores SY, Kamynina E, Plant PJ, Tauxe C, Thomas MA, Münster C, Chraïbi A, Pratt JH, Horisberger JD, Pearce D, Loffing J, Staub O.
    EMBO J; 2001 Dec 17; 20(24):7052-9. PubMed ID: 11742982
    [Abstract] [Full Text] [Related]

  • 20. cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2.
    Snyder PM, Olson DR, Kabra R, Zhou R, Steines JC.
    J Biol Chem; 2004 Oct 29; 279(44):45753-8. PubMed ID: 15328345
    [Abstract] [Full Text] [Related]

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