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Journal Abstract Search

287 related items for PubMed ID: 18987624

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  • 2. The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
    Elsby R, Gillen M, Butters C, Imisson G, Sharma P, Smith V, Surry DD.
    Drug Metab Dispos; 2011 Feb; 39(2):275-82. PubMed ID: 21075975
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  • 3. Refining the in vitro and in vivo critical parameters for P-glycoprotein, [I]/IC50 and [I2]/IC50, that allow for the exclusion of drug candidates from clinical digoxin interaction studies.
    Cook JA, Feng B, Fenner KS, Kempshall S, Liu R, Rotter C, Smith DA, Troutman MD, Ullah M, Lee CA.
    Mol Pharm; 2010 Apr 05; 7(2):398-411. PubMed ID: 20025245
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  • 4. Quantitative investigation of the impact of P-glycoprotein inhibition on drug transport across blood-brain barrier in rats.
    Sugimoto H, Hirabayashi H, Kimura Y, Furuta A, Amano N, Moriwaki T.
    Drug Metab Dispos; 2011 Jan 05; 39(1):8-14. PubMed ID: 20962062
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  • 7. 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
    Zhang J, Zhou F, Wu X, Gu Y, Ai H, Zheng Y, Li Y, Zhang X, Hao G, Sun J, Peng Y, Wang G.
    Drug Metab Dispos; 2010 Dec 05; 38(12):2179-87. PubMed ID: 20837659
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  • 10. Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers.
    Ding R, Tayrouz Y, Riedel KD, Burhenne J, Weiss J, Mikus G, Haefeli WE.
    Clin Pharmacol Ther; 2004 Jul 05; 76(1):73-84. PubMed ID: 15229466
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  • 11. In vitro P-glycoprotein interactions and steady-state pharmacokinetic interactions between tolvaptan and digoxin in healthy subjects.
    Shoaf SE, Ohzone Y, Ninomiya S, Furukawa M, Bricmont P, Kashiyama E, Mallikaarjun S.
    J Clin Pharmacol; 2011 May 05; 51(5):761-9. PubMed ID: 20679500
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  • 12. Caco-2 cell methodology and inhibition of the P-glycoprotein transport of digoxin by Aloe vera juice.
    Djuv A, Nilsen OG.
    Phytother Res; 2008 Dec 05; 22(12):1623-8. PubMed ID: 19003953
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  • 13. Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells.
    Hansen TS, Nilsen OG.
    Phytother Res; 2009 Jan 05; 23(1):86-91. PubMed ID: 18688789
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  • 14. Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design.
    Reitman ML, Chu X, Cai X, Yabut J, Venkatasubramanian R, Zajic S, Stone JA, Ding Y, Witter R, Gibson C, Roupe K, Evers R, Wagner JA, Stoch A.
    Clin Pharmacol Ther; 2011 Feb 05; 89(2):234-42. PubMed ID: 21191377
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  • 16. Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.
    Wagner AD, Kolb JM, Ozbal CC, Herbst JJ, Olah TV, Weller HN, Zvyaga TA, Shou WZ.
    Rapid Commun Mass Spectrom; 2011 May 15; 25(9):1231-40. PubMed ID: 21488121
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  • 17. Development of a quantitative LC-MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay.
    Smalley J, Marino AM, Xin B, Olah T, Balimane PV.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jul 01; 854(1-2):260-7. PubMed ID: 17524973
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  • 18. In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
    Kishimoto W, Ishiguro N, Ludwig-Schwellinger E, Ebner T, Schaefer O.
    Drug Metab Dispos; 2014 Feb 01; 42(2):257-63. PubMed ID: 24212378
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  • 20. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
    Acharya P, O'Connor MP, Polli JW, Ayrton A, Ellens H, Bentz J.
    Drug Metab Dispos; 2008 Feb 01; 36(2):452-60. PubMed ID: 17967933
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