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Journal Abstract Search

194 related items for PubMed ID: 18992850

  • 1. Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.
    Kadoshima-Yamaoka K, Murakawa M, Goto M, Tanaka Y, Inoue H, Murafuji H, Hayashi Y, Nagahira K, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.
    Int Immunopharmacol; 2009 Jan; 9(1):97-102. PubMed ID: 18992850
    [Abstract] [Full Text] [Related]

  • 2. ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-gamma production by mouse activated T lymphocytes.
    Kadoshima-Yamaoka K, Murakawa M, Goto M, Tanaka Y, Inoue H, Murafuji H, Nagahira A, Hayashi Y, Nagahira K, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.
    Immunol Lett; 2009 Feb 21; 122(2):193-7. PubMed ID: 19195485
    [Abstract] [Full Text] [Related]

  • 3. Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo.
    Goto M, Kadoshima-Yamaoka K, Murakawa M, Yoshioka R, Tanaka Y, Inoue H, Murafuji H, Kanki S, Hayashi Y, Nagahira K, Ogata A, Nakatsuka T, Fukuda Y.
    Eur J Pharmacol; 2010 May 10; 633(1-3):93-7. PubMed ID: 20132810
    [Abstract] [Full Text] [Related]

  • 4. ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.
    Kadoshima-Yamaoka K, Goto M, Murakawa M, Yoshioka R, Tanaka Y, Inoue H, Murafuji H, Kanki S, Hayashi Y, Nagahira K, Ogata A, Nakatsuka T, Fukuda Y.
    Eur J Pharmacol; 2009 Jun 24; 613(1-3):163-6. PubMed ID: 19379723
    [Abstract] [Full Text] [Related]

  • 5. Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.
    Goto M, Murakawa M, Kadoshima-Yamaoka K, Tanaka Y, Inoue H, Murafuji H, Hayashi Y, Miura K, Nakatsuka T, Nagahira K, Chamoto K, Fukuda Y, Nishimura T.
    Cell Immunol; 2009 Jun 24; 258(2):147-51. PubMed ID: 19477436
    [Abstract] [Full Text] [Related]

  • 6. Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling.
    Hu H, Dong Y, Feng P, Fechner J, Hamawy M, Knechtle SJ.
    Transplantation; 2003 Apr 15; 75(7):1075-7. PubMed ID: 12698107
    [Abstract] [Full Text] [Related]

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  • 8. A sensitive flow cytometry-based cytotoxic T-lymphocyte assay through detection of cleaved caspase 3 in target cells.
    He L, Hakimi J, Salha D, Miron I, Dunn P, Radvanyi L.
    J Immunol Methods; 2005 Sep 15; 304(1-2):43-59. PubMed ID: 16076473
    [Abstract] [Full Text] [Related]

  • 9. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
    Zhu B, Kelly J, Vemavarapu L, Thompson WJ, Strada SJ.
    Biochem Pharmacol; 2004 Aug 01; 68(3):479-91. PubMed ID: 15242814
    [Abstract] [Full Text] [Related]

  • 10. Norepinephrine-mediated inhibition of antitumor cytotoxic T lymphocyte generation involves a beta-adrenergic receptor mechanism and decreased TNF-alpha gene expression.
    Kalinichenko VV, Mokyr MB, Graf LH, Cohen RL, Chambers DA.
    J Immunol; 1999 Sep 01; 163(5):2492-9. PubMed ID: 10452985
    [Abstract] [Full Text] [Related]

  • 11. Effect of orally administered rolipram, a phosphodiesterase 4 inhibitor, on a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application.
    Harada D, Tsukumo Y, Takashima Y, Manabe H.
    Eur J Pharmacol; 2006 Feb 17; 532(1-2):128-37. PubMed ID: 16442096
    [Abstract] [Full Text] [Related]

  • 12. Rational design of cytotoxic T-cell inhibitors.
    Tretiakova AP, Little CS, Blank KJ, Jameson BA.
    Nat Biotechnol; 2000 Sep 17; 18(9):984-8. PubMed ID: 10973221
    [Abstract] [Full Text] [Related]

  • 13. Dipeptidyl peptidase I is enriched in granules of in vitro- and in vivo-activated cytotoxic T lymphocytes.
    Brown GR, McGuire MJ, Thiele DL.
    J Immunol; 1993 Jun 01; 150(11):4733-42. PubMed ID: 8496587
    [Abstract] [Full Text] [Related]

  • 14. The role of cyclic AMP in modulating cytotoxic T lymphocytes. II. Sequential changes during culture in responsiveness of cytotoxic lymphocytes to cyclic AMP-active agents.
    Plaut M, Marone G, Gillespie E.
    J Immunol; 1983 Dec 01; 131(6):2945-52. PubMed ID: 6315818
    [Abstract] [Full Text] [Related]

  • 15. Decreased sensitivity to cAMP in the in vitro generation of memory splenic cytotoxic T-lymphocytes from aged mice: role of phosphodiesterase.
    Bender BS, Bell WE, Taylor S, Scarpace PJ.
    J Pharmacol Exp Ther; 1993 Mar 01; 264(3):1381-6. PubMed ID: 8383747
    [Abstract] [Full Text] [Related]

  • 16. Identification of potent pyrimidine inhibitors of phosphodiesterase 7 (PDE7) and their ability to inhibit T cell proliferation.
    Guo J, Watson A, Kempson J, Carlsen M, Barbosa J, Stebbins K, Lee D, Dodd J, Nadler SG, McKinnon M, Barrish J, Pitts WJ.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):1935-8. PubMed ID: 19272774
    [Abstract] [Full Text] [Related]

  • 17. Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.
    Smith SJ, Cieslinski LB, Newton R, Donnelly LE, Fenwick PS, Nicholson AG, Barnes PJ, Barnette MS, Giembycz MA.
    Mol Pharmacol; 2004 Dec 01; 66(6):1679-89. PubMed ID: 15371556
    [Abstract] [Full Text] [Related]

  • 18. Induction of endotoxin tolerance inhibits alloimmune responses.
    Ishiyama K, Ohdan H, Tokita D, Shishida M, Tanaka Y, Irei T, Asahara T.
    Transpl Immunol; 2006 Nov 01; 16(3-4):158-65. PubMed ID: 17138048
    [Abstract] [Full Text] [Related]

  • 19. In vivo and in vitro immunosuppressive effects of benzo[k]fluoranthene in female Balb/c mice.
    Jeon TW, Jin CH, Lee SK, Lee DW, Hyun SH, Kim GH, Jun IH, Lee BM, Yum YN, Kim JK, Kim OH, Jeong TC.
    J Toxicol Environ Health A; 2005 Dec 10; 68(23-24):2033-50. PubMed ID: 16326422
    [Abstract] [Full Text] [Related]

  • 20. The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity.
    Riquelme E, Carreño LJ, González PA, Kalergis AM.
    Eur J Immunol; 2009 Aug 10; 39(8):2259-69. PubMed ID: 19637198
    [Abstract] [Full Text] [Related]

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