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Journal Abstract Search

247 related items for PubMed ID: 18997389

  • 1.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 2. Selectivity of microbial acyl-CoA: cholesterol acyltransferase inhibitors toward isozymes.
    Ohshiro T, Rudel LL, Omura S, Tomoda H.
    J Antibiot (Tokyo); 2007 Jan; 60(1):43-51. PubMed ID: 17390588
    [Abstract] [Full Text] [Related]

  • 3. Selective inhibition of acyl-CoA:cholesterol acyltransferase 2 isozyme by flavasperone and sterigmatocystin from Aspergillus species.
    Sakai K, Ohte S, Ohshiro T, Matsuda D, Masuma R, Rudel LL, Tomoda H.
    J Antibiot (Tokyo); 2008 Sep; 61(9):568-72. PubMed ID: 19160525
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1.
    Ohtawa M, Yamazaki H, Ohte S, Matsuda D, Ohshiro T, Rudel LL, Omura S, Tomoda H, Nagamitsu T.
    Bioorg Med Chem Lett; 2013 Mar 01; 23(5):1285-7. PubMed ID: 23369538
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 3.
    Ohtawa M, Yamazaki H, Ohte S, Matsuda D, Ohshiro T, Rudel LL, Ōmura S, Tomoda H, Nagamitsu T.
    Bioorg Med Chem Lett; 2013 Jul 01; 23(13):3798-801. PubMed ID: 23711919
    [Abstract] [Full Text] [Related]

  • 6. Penicillium griseofulvum F1959, high-production strain of pyripyropene a, specific inhibitor of acyl-CoA: cholesterol acyltransferase 2.
    Choi JH, Rho MC, Lee SW, Choi JN, Lee HJ, Bae KS, Kim K, Kim YK.
    J Microbiol Biotechnol; 2008 Oct 01; 18(10):1663-5. PubMed ID: 18955816
    [Abstract] [Full Text] [Related]

  • 7. Isoform-specific inhibitors of ACATs: recent advances and promising developments.
    Ohshiro T, Tomoda H.
    Future Med Chem; 2011 Dec 01; 3(16):2039-61. PubMed ID: 22098352
    [Abstract] [Full Text] [Related]

  • 8. Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
    Ohshiro T, Matsuda D, Sakai K, Degirolamo C, Yagyu H, Rudel LL, Omura S, Ishibashi S, Tomoda H.
    Arterioscler Thromb Vasc Biol; 2011 May 01; 31(5):1108-15. PubMed ID: 21393580
    [Abstract] [Full Text] [Related]

  • 9. The selectivity of beauveriolide derivatives in inhibition toward the two isozymes of acyl-CoA: cholesterol acyltransferase.
    Ohshiro T, Matsuda D, Nagai K, Doi T, Sunazuka T, Takahashi T, Rudel LL, Omura S, Tomoda H.
    Chem Pharm Bull (Tokyo); 2009 Apr 01; 57(4):377-81. PubMed ID: 19336931
    [Abstract] [Full Text] [Related]

  • 10. Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents.
    Tomoda H, Doi T.
    Acc Chem Res; 2008 Jan 01; 41(1):32-9. PubMed ID: 17803269
    [Abstract] [Full Text] [Related]

  • 11.
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    [No Abstract] [Full Text] [Related]

  • 12. Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness.
    Lada AT, Davis M, Kent C, Chapman J, Tomoda H, Omura S, Rudel LL.
    J Lipid Res; 2004 Feb 01; 45(2):378-86. PubMed ID: 14617738
    [Abstract] [Full Text] [Related]

  • 13. New verticilides, inhibitors of acyl-CoA:cholesterol acyltransferase, produced by Verticillium sp. FKI-2679.
    Ohshiro T, Matsuda D, Kazuhiro T, Uchida R, Nonaka K, Masuma R, Tomoda H.
    J Antibiot (Tokyo); 2012 May 01; 65(5):255-62. PubMed ID: 22415459
    [Abstract] [Full Text] [Related]

  • 14. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety.
    Obata R, Sunazuka T, Tian Z, Tomoda H, Harigaya Y, Omura S.
    J Antibiot (Tokyo); 1997 Mar 01; 50(3):229-36. PubMed ID: 9127194
    [Abstract] [Full Text] [Related]

  • 15. A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.
    An S, Cho KH, Lee WS, Lee JO, Paik YK, Jeong TS.
    FEBS Lett; 2006 May 15; 580(11):2741-9. PubMed ID: 16647063
    [Abstract] [Full Text] [Related]

  • 16. ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver.
    Parini P, Davis M, Lada AT, Erickson SK, Wright TL, Gustafsson U, Sahlin S, Einarsson C, Eriksson M, Angelin B, Tomoda H, Omura S, Willingham MC, Rudel LL.
    Circulation; 2004 Oct 05; 110(14):2017-23. PubMed ID: 15451793
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 2.
    Ohtawa M, Yamazaki H, Matsuda D, Ohshiro T, Rudel LL, Ōmura S, Tomoda H, Nagamitsu T.
    Bioorg Med Chem Lett; 2013 May 01; 23(9):2659-62. PubMed ID: 23535327
    [Abstract] [Full Text] [Related]

  • 18. Chemical modification and structure-activity relationships of pyripyropenes. 2. 1,11-Cyclic analogs.
    Obata R, Sunazuka T, Kato Y, Tomoda H, Harigaya Y, Omura S.
    J Antibiot (Tokyo); 1996 Nov 01; 49(11):1149-56. PubMed ID: 8982344
    [Abstract] [Full Text] [Related]

  • 19. Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors.
    Ohtawa M, Arima S, Ichida N, Terayama T, Ohno H, Yamazaki T, Ohshiro T, Sato N, Omura S, Tomoda H, Nagamitsu T.
    ChemMedChem; 2018 Mar 06; 13(5):411-421. PubMed ID: 29323466
    [Abstract] [Full Text] [Related]

  • 20. Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe.
    Kitayama K, Tanimoto T, Koga T, Terasaka N, Fujioka T, Inaba T.
    Eur J Pharmacol; 2006 Jul 01; 540(1-3):121-30. PubMed ID: 16730694
    [Abstract] [Full Text] [Related]

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