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407 related items for PubMed ID: 19001549

  • 1. Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes.
    Ikubo M, Wada T, Fukui K, Ishiki M, Ishihara H, Asano T, Tsuneki H, Sasaoka T.
    Am J Physiol Endocrinol Metab; 2009 Jan; 296(1):E157-64. PubMed ID: 19001549
    [Abstract] [Full Text] [Related]

  • 2. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.
    Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.
    Mol Cell Biol; 2001 Mar; 21(5):1633-46. PubMed ID: 11238900
    [Abstract] [Full Text] [Related]

  • 3. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.
    Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.
    J Biol Chem; 2005 Jun 10; 280(23):22523-9. PubMed ID: 15824124
    [Abstract] [Full Text] [Related]

  • 4. SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.
    Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M.
    J Biol Chem; 2004 Apr 09; 279(15):14835-43. PubMed ID: 14744864
    [Abstract] [Full Text] [Related]

  • 5. Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.
    Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M.
    Endocrinology; 2004 Jul 09; 145(7):3215-23. PubMed ID: 15044364
    [Abstract] [Full Text] [Related]

  • 6. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H, Katagiri H, Funaki M, Anai M, Inukai K, Fukushima Y, Sakoda H, Ogihara T, Onishi Y, Fujishiro M, Kikuchi M, Oka Y, Asano T.
    Mol Endocrinol; 2001 Aug 09; 15(8):1411-22. PubMed ID: 11463863
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes.
    Sasaoka T, Fukui K, Wada T, Murakami S, Kawahara J, Ishihara H, Funaki M, Asano T, Kobayashi M.
    Diabetologia; 2005 Feb 09; 48(2):336-44. PubMed ID: 15654601
    [Abstract] [Full Text] [Related]

  • 8. SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.
    Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M.
    Diabetologia; 2001 Oct 09; 44(10):1258-67. PubMed ID: 11692174
    [Abstract] [Full Text] [Related]

  • 9. Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors.
    Ishihara H, Sasaoka T, Ishiki M, Wada T, Hori H, Kagawa S, Kobayashi M.
    Mol Endocrinol; 2002 Oct 09; 16(10):2371-81. PubMed ID: 12351701
    [Abstract] [Full Text] [Related]

  • 10. The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners.
    Onnockx S, De Schutter J, Blockmans M, Xie J, Jacobs C, Vanderwinden JM, Erneux C, Pirson I.
    J Cell Physiol; 2008 Jan 09; 214(1):260-72. PubMed ID: 17620296
    [Abstract] [Full Text] [Related]

  • 11. Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes.
    Artemenko Y, Gagnon A, Sorisky A.
    J Cell Physiol; 2009 Jan 09; 218(1):228-36. PubMed ID: 18814181
    [Abstract] [Full Text] [Related]

  • 12. Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.
    Sasaoka T, Kikuchi K, Wada T, Sato A, Hori H, Murakami S, Fukui K, Ishihara H, Aota R, Kimura I, Kobayashi M.
    Endocrinology; 2003 Sep 09; 144(9):4204-14. PubMed ID: 12933696
    [Abstract] [Full Text] [Related]

  • 13. PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.
    Gupta A, Dey CS.
    Mol Cell Endocrinol; 2009 Oct 15; 309(1-2):55-62. PubMed ID: 19501627
    [Abstract] [Full Text] [Related]

  • 14. Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity.
    Sasaoka T, Wada T, Tsuneki H.
    Pharmacol Ther; 2006 Dec 15; 112(3):799-809. PubMed ID: 16842857
    [Abstract] [Full Text] [Related]

  • 15. Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes.
    Artemenko Y, Gagnon A, Ibrahim S, Sorisky A.
    J Cell Physiol; 2007 Jun 15; 211(3):598-607. PubMed ID: 17219406
    [Abstract] [Full Text] [Related]

  • 16. Regulation of endogenous SH2 domain-containing inositol 5-phosphatase (SHIP2) in 3T3-L1 and human preadipocytes.
    Gagnon A, Artemenko Y, Crapper T, Sorisky A.
    J Cell Physiol; 2003 Nov 15; 197(2):243-50. PubMed ID: 14502564
    [Abstract] [Full Text] [Related]

  • 17. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM.
    Mol Cell Biol; 2004 Oct 15; 24(19):8778-89. PubMed ID: 15367694
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