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Journal Abstract Search

230 related items for PubMed ID: 19010906

  • 1. Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.
    Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C.
    Cancer Res; 2008 Nov 15; 68(22):9323-30. PubMed ID: 19010906
    [Abstract] [Full Text] [Related]

  • 2. Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.
    Periyasamy-Thandavan S, Jackson WH, Samaddar JS, Erickson B, Barrett JR, Raney L, Gopal E, Ganapathy V, Hill WD, Bhalla KN, Schoenlein PV.
    Autophagy; 2010 Jan 15; 6(1):19-35. PubMed ID: 20110775
    [Abstract] [Full Text] [Related]

  • 3. Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis.
    Kraus M, Malenke E, Gogel J, Müller H, Rückrich T, Overkleeft H, Ovaa H, Koscielniak E, Hartmann JT, Driessen C.
    Mol Cancer Ther; 2008 Jul 15; 7(7):1940-8. PubMed ID: 18645004
    [Abstract] [Full Text] [Related]

  • 4. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
    Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ.
    Cancer Res; 2005 Dec 15; 65(24):11510-9. PubMed ID: 16357160
    [Abstract] [Full Text] [Related]

  • 5. TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response.
    Nowis D, McConnell EJ, Dierlam L, Palamarchuk A, Lass A, Wójcik C.
    Int J Cancer; 2007 Jul 15; 121(2):431-41. PubMed ID: 17373661
    [Abstract] [Full Text] [Related]

  • 6. Role of CAAT/enhancer binding protein homologous protein in panobinostat-mediated potentiation of bortezomib-induced lethal endoplasmic reticulum stress in mantle cell lymphoma cells.
    Rao R, Nalluri S, Fiskus W, Savoie A, Buckley KM, Ha K, Balusu R, Joshi A, Coothankandaswamy V, Tao J, Sotomayor E, Atadja P, Bhalla KN.
    Clin Cancer Res; 2010 Oct 01; 16(19):4742-54. PubMed ID: 20647473
    [Abstract] [Full Text] [Related]

  • 7. Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells.
    Dong H, Chen L, Chen X, Gu H, Gao G, Gao Y, Dong B.
    Leuk Lymphoma; 2009 Jun 01; 50(6):974-84. PubMed ID: 19391038
    [Abstract] [Full Text] [Related]

  • 8. Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition.
    Hu J, Dang N, Menu E, De Bruyne E, Xu D, Van Camp B, Van Valckenborgh E, Vanderkerken K.
    Blood; 2012 Jan 19; 119(3):826-37. PubMed ID: 22128141
    [Abstract] [Full Text] [Related]

  • 9. Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells.
    Armstrong JL, Flockhart R, Veal GJ, Lovat PE, Redfern CP.
    J Biol Chem; 2010 Feb 26; 285(9):6091-100. PubMed ID: 20022965
    [Abstract] [Full Text] [Related]

  • 10. Clarithromycin enhances bortezomib-induced cytotoxicity via endoplasmic reticulum stress-mediated CHOP (GADD153) induction and autophagy in breast cancer cells.
    Komatsu S, Miyazawa K, Moriya S, Takase A, Naito M, Inazu M, Kohno N, Itoh M, Tomoda A.
    Int J Oncol; 2012 Apr 26; 40(4):1029-39. PubMed ID: 22200786
    [Abstract] [Full Text] [Related]

  • 11. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells.
    Obeng EA, Carlson LM, Gutman DM, Harrington WJ, Lee KP, Boise LH.
    Blood; 2006 Jun 15; 107(12):4907-16. PubMed ID: 16507771
    [Abstract] [Full Text] [Related]

  • 12. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
    Babcock JT, Nguyen HB, He Y, Hendricks JW, Wek RC, Quilliam LA.
    J Biol Chem; 2013 May 31; 288(22):15687-98. PubMed ID: 23612979
    [Abstract] [Full Text] [Related]

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  • 14. Mucin production determines sensitivity to bortezomib and gemcitabine in pancreatic cancer cells.
    Wissniowski TT, Meister S, Hahn EG, Kalden JR, Voll R, Ocker M.
    Int J Oncol; 2012 May 31; 40(5):1581-9. PubMed ID: 22266985
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  • 16. Regulation of autophagy by ATF4 in response to severe hypoxia.
    Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL.
    Oncogene; 2010 Aug 05; 29(31):4424-35. PubMed ID: 20514020
    [Abstract] [Full Text] [Related]

  • 17. Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells.
    Gu H, Chen X, Gao G, Dong H.
    Mol Cancer Ther; 2008 Aug 05; 7(8):2298-307. PubMed ID: 18723477
    [Abstract] [Full Text] [Related]

  • 18. Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis.
    Hirai M, Kadowaki N, Kitawaki T, Fujita H, Takaori-Kondo A, Fukui R, Miyake K, Maeda T, Kamihira S, Miyachi Y, Uchiyama T.
    Blood; 2011 Jan 13; 117(2):500-9. PubMed ID: 20956804
    [Abstract] [Full Text] [Related]

  • 19. Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress.
    Dasmahapatra G, Lembersky D, Rahmani M, Kramer L, Friedberg J, Fisher RI, Dent P, Grant S.
    Cancer Biol Ther; 2009 May 13; 8(9):808-19. PubMed ID: 19270531
    [Abstract] [Full Text] [Related]

  • 20. Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.
    Sun S, Han J, Ralph WM, Chandrasekaran A, Liu K, Auborn KJ, Carter TH.
    Cell Stress Chaperones; 2004 Mar 13; 9(1):76-87. PubMed ID: 15270080
    [Abstract] [Full Text] [Related]

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