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115 related items for PubMed ID: 19014910

  • 1. Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells.
    Yang SY, Jia XZ, Feng LY, Li SY, An GS, Ni JH, Jia HT.
    Biochem Pharmacol; 2009 Feb 01; 77(3):433-43. PubMed ID: 19014910
    [Abstract] [Full Text] [Related]

  • 2. Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II.
    Li Y, Luan Y, Qi X, Li M, Gong L, Xue X, Wu X, Wu Y, Chen M, Xing G, Yao J, Ren J.
    Toxicol Sci; 2010 Dec 01; 118(2):435-43. PubMed ID: 20855424
    [Abstract] [Full Text] [Related]

  • 3. 8-Chloro-adenosine inhibits growth at least partly by interfering with actin polymerization in cultured human lung cancer cells.
    Gu YY, Zhang HY, Zhang HJ, Li SY, Ni JH, Jia HT.
    Biochem Pharmacol; 2006 Aug 28; 72(5):541-50. PubMed ID: 16844099
    [Abstract] [Full Text] [Related]

  • 4. Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats.
    Gandhi V, Chen W, Ayres M, Rhie JK, Madden TL, Newman RA.
    Cancer Chemother Pharmacol; 2002 Aug 28; 50(2):85-94. PubMed ID: 12172971
    [Abstract] [Full Text] [Related]

  • 5. 8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells.
    Gandhi V, Ayres M, Halgren RG, Krett NL, Newman RA, Rosen ST.
    Cancer Res; 2001 Jul 15; 61(14):5474-9. PubMed ID: 11454694
    [Abstract] [Full Text] [Related]

  • 6. RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells.
    Stellrecht CM, Rodriguez CO, Ayres M, Gandhi V.
    Cancer Res; 2003 Nov 15; 63(22):7968-74. PubMed ID: 14633728
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells.
    Jia XZ, Yang SY, Zhou J, Li SY, Ni JH, An GS, Jia HT.
    Biochem Pharmacol; 2009 Mar 01; 77(5):770-80. PubMed ID: 19059218
    [Abstract] [Full Text] [Related]

  • 8. Induction of p14ARF by E2F1 contributes to 8-chloro-adenosine-induced apoptosis in human lung cancer H1299 cells.
    Li WJ, Gu YY, Zhang HJ, Zhou J, Jia HT.
    Chemotherapy; 2009 Mar 01; 55(5):335-43. PubMed ID: 19641316
    [Abstract] [Full Text] [Related]

  • 9. Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition.
    Cai YJ, Lu JJ, Zhu H, Xie H, Huang M, Lin LP, Zhang XW, Ding J.
    Free Radic Biol Med; 2008 Sep 01; 45(5):627-35. PubMed ID: 18582559
    [Abstract] [Full Text] [Related]

  • 10. Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.
    López-Lázaro M, Willmore E, Jobson A, Gilroy KL, Curtis H, Padget K, Austin CA.
    J Nat Prod; 2007 Dec 01; 70(12):1884-8. PubMed ID: 18076140
    [Abstract] [Full Text] [Related]

  • 11. Structural determinants of the catalytic inhibition of human topoisomerase IIα by salicylate analogs and salicylate-based drugs.
    Bau JT, Kurz EU.
    Biochem Pharmacol; 2014 Jun 15; 89(4):464-76. PubMed ID: 24695359
    [Abstract] [Full Text] [Related]

  • 12. Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II.
    Hasinoff BB, Wu X, Begleiter A, Guziec LJ, Guziec F, Giorgianni A, Yang S, Jiang Y, Yalowich JC.
    Cancer Chemother Pharmacol; 2006 Jan 15; 57(2):221-33. PubMed ID: 16010589
    [Abstract] [Full Text] [Related]

  • 13. DNA topoisomerases I and II in human mature sperm cells: characterization and unique properties.
    Har-Vardi I, Mali R, Breietman M, Sonin Y, Albotiano S, Levitas E, Potashnik G, Priel E.
    Hum Reprod; 2007 Aug 15; 22(8):2183-9. PubMed ID: 17656417
    [Abstract] [Full Text] [Related]

  • 14. E2F1-mediated DNA damage is implicated in 8-Cl-adenosine-induced chromosome missegregation and apoptosis in human lung cancer H1299 cells.
    Han YY, Zhou Z, Cao JX, Jin YQ, Li SY, Ni JH, An GS, Zhang YX, Jia HT.
    Mol Cell Biochem; 2013 Dec 15; 384(1-2):187-96. PubMed ID: 24037421
    [Abstract] [Full Text] [Related]

  • 15. E2F1 enhances 8-chloro-adenosine-induced G2/M arrest and apoptosis in A549 and H1299 lung cancer cells.
    Duan HY, Cao JX, Qi JJ, Wu GS, Li SY, An GS, Jia HT, Cai WW, Ni JH.
    Biochemistry (Mosc); 2012 Mar 15; 77(3):261-9. PubMed ID: 22803943
    [Abstract] [Full Text] [Related]

  • 16. 2-Chloroadenosine: a selective lethal effect to mouse macrophages and its mechanism.
    Saito T, Yamaguchi J.
    J Immunol; 1985 Mar 15; 134(3):1815-22. PubMed ID: 3968433
    [Abstract] [Full Text] [Related]

  • 17. Phenoxodiol (2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl)), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex.
    Constantinou AI, Husband A.
    Anticancer Res; 2002 Mar 15; 22(5):2581-5. PubMed ID: 12529967
    [Abstract] [Full Text] [Related]

  • 18. Salvicine functions as novel topoisomerase II poison by binding to ATP pocket.
    Hu CX, Zuo ZL, Xiong B, Ma JG, Geng MY, Lin LP, Jiang HL, Ding J.
    Mol Pharmacol; 2006 Nov 15; 70(5):1593-601. PubMed ID: 16914642
    [Abstract] [Full Text] [Related]

  • 19. Topoisomerase II beta levels are a determinant of melphalan-induced DNA crosslinks and sensitivity to cell death.
    Emmons M, Boulware D, Sullivan DM, Hazlehurst LA.
    Biochem Pharmacol; 2006 Jun 28; 72(1):11-8. PubMed ID: 16678798
    [Abstract] [Full Text] [Related]

  • 20. 8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway.
    Ding HY, Yang WY, Zhang LH, Li L, Xie F, Li HY, Chen XY, Tu Z, Li Y, Chen Y, Yang SY.
    Cell Transplant; 2020 Jun 28; 29():963689720958656. PubMed ID: 32907379
    [Abstract] [Full Text] [Related]

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