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309 related items for PubMed ID: 19017849
1. New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity. Storme T, Deroussent A, Mercier L, Prost E, Re M, Munier F, Martens T, Bourget P, Vassal G, Royer J, Paci A. J Pharmacol Exp Ther; 2009 Feb; 328(2):598-609. PubMed ID: 19017849 [Abstract] [Full Text] [Related]
3. Excretion kinetics of ifosfamide side-chain metabolites in children on continuous and short-term infusion. Silies H, Blaschke G, Hohenlöchter B, Rossi R, Jürgens H, Boos J. Int J Clin Pharmacol Ther; 1998 May; 36(5):246-52. PubMed ID: 9629987 [Abstract] [Full Text] [Related]
4. Oxazaphosphorines: new therapeutic strategies for an old class of drugs. Giraud B, Hebert G, Deroussent A, Veal GJ, Vassal G, Paci A. Expert Opin Drug Metab Toxicol; 2010 Aug; 6(8):919-38. PubMed ID: 20446865 [Abstract] [Full Text] [Related]
5. High-performance liquid chromatographic-fluorescent method to determine chloroacetaldehyde, a neurotoxic metabolite of the anticancer drug ifosfamide, in plasma and in liver microsomal incubations. Huang Z, Waxman DJ. Anal Biochem; 1999 Aug 15; 273(1):117-25. PubMed ID: 10452807 [Abstract] [Full Text] [Related]
6. Activation of oxazaphosphorines by cytochrome P450: application to gene-directed enzyme prodrug therapy for cancer. Roy P, Waxman DJ. Toxicol In Vitro; 2006 Mar 15; 20(2):176-86. PubMed ID: 16293390 [Abstract] [Full Text] [Related]
8. Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept. Skarbek C, Lesueur LL, Chapuis H, Deroussent A, Pioche Durieu C, Daville A, Caron J, Rivard M, Martens T, Bertrand JR, Le Cam E, Vassal G, Couvreur P, Desmaele D, Paci A. J Med Chem; 2015 Jan 22; 58(2):705-17. PubMed ID: 25494842 [Abstract] [Full Text] [Related]
9. Antitumor activity of methoxymorpholinyl doxorubicin: potentiation by cytochrome P450 3A metabolism. Lu H, Waxman DJ. Mol Pharmacol; 2005 Jan 22; 67(1):212-9. PubMed ID: 15465924 [Abstract] [Full Text] [Related]
10. A tubule cell model for ifosfamide nephrotoxicity. Aleksa K, Halachmi N, Ito S, Koren G. Can J Physiol Pharmacol; 2005 Jun 22; 83(6):499-508. PubMed ID: 16049550 [Abstract] [Full Text] [Related]
11. The effect of N-acetylcysteine on the antitumor activity of ifosfamide. Chen N, Hanly L, Rieder M, Yeger H, Koren G. Can J Physiol Pharmacol; 2011 May 22; 89(5):335-43. PubMed ID: 21609276 [Abstract] [Full Text] [Related]
16. Renal ontogeny of ifosfamide nephrotoxicity. Aleksa K, Halachmi N, Ito S, Koren G. J Lab Clin Med; 2004 Dec 22; 144(6):285-93. PubMed ID: 15614250 [Abstract] [Full Text] [Related]
17. Metabolism of ifosfamide to chloroacetaldehyde contributes to antitumor activity in vivo. Börner K, Kisro J, Brüggemann SK, Hagenah W, Peters SO, Wagner T. Drug Metab Dispos; 2000 May 22; 28(5):573-6. PubMed ID: 10772637 [Abstract] [Full Text] [Related]
18. Suspected ifosfamide-induced neurotoxicity. McVay JI, Wood AM. Pharmacotherapy; 1999 Dec 22; 19(12):1450-5. PubMed ID: 10600096 [Abstract] [Full Text] [Related]
19. Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip. Choucha-Snouber L, Aninat C, Grsicom L, Madalinski G, Brochot C, Poleni PE, Razan F, Guillouzo CG, Legallais C, Corlu A, Leclerc E. Biotechnol Bioeng; 2013 Feb 22; 110(2):597-608. PubMed ID: 22887128 [Abstract] [Full Text] [Related]