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217 related items for PubMed ID: 19038232

  • 1. Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.
    Sánchez Y, Amrán D, de Blas E, Aller P.
    Biochem Pharmacol; 2009 Feb 01; 77(3):384-96. PubMed ID: 19038232
    [Abstract] [Full Text] [Related]

  • 2. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y, Calle C, de Blas E, Aller P.
    Chem Biol Interact; 2009 Nov 10; 182(1):37-44. PubMed ID: 19720055
    [Abstract] [Full Text] [Related]

  • 3. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
    Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P.
    J Pharmacol Exp Ther; 2010 Oct 10; 335(1):114-23. PubMed ID: 20605902
    [Abstract] [Full Text] [Related]

  • 4. Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.
    Ozpolat B, Akar U, Steiner M, Zorrilla-Calancha I, Tirado-Gomez M, Colburn N, Danilenko M, Kornblau S, Berestein GL.
    Mol Cancer Res; 2007 Jan 10; 5(1):95-108. PubMed ID: 17259349
    [Abstract] [Full Text] [Related]

  • 5. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.
    Rosato RR, Almenara JA, Grant S.
    Cancer Res; 2003 Jul 01; 63(13):3637-45. PubMed ID: 12839953
    [Abstract] [Full Text] [Related]

  • 6. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec 01; 209(3):1006-15. PubMed ID: 16972261
    [Abstract] [Full Text] [Related]

  • 7. Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.
    Calviño E, Estañ MC, Simón GP, Sancho P, Boyano-Adánez Mdel C, de Blas E, Bréard J, Aller P.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1619-29. PubMed ID: 21889928
    [Abstract] [Full Text] [Related]

  • 8. Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation.
    Su JC, Lin KL, Chien CM, Lu CM, Chen YL, Chang LS, Lin SR.
    Life Sci; 2009 Sep 23; 85(13-14):505-16. PubMed ID: 19699753
    [Abstract] [Full Text] [Related]

  • 9. Akt regulates vitamin D3-induced leukemia cell functional differentiation via Raf/MEK/ERK MAPK signaling.
    Wang J, Zhao Y, Kauss MA, Spindel S, Lian H.
    Eur J Cell Biol; 2009 Feb 23; 88(2):103-15. PubMed ID: 19058874
    [Abstract] [Full Text] [Related]

  • 10. 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
    Estañ MC, Calviño E, de Blas E, Boyano-Adánez Mdel C, Mena ML, Gómez-Gómez M, Rial E, Aller P.
    Biochem Pharmacol; 2012 Dec 15; 84(12):1604-16. PubMed ID: 23041229
    [Abstract] [Full Text] [Related]

  • 11. Betuletol 3-methyl ether induces G(2)-M phase arrest and activates the sphingomyelin and MAPK pathways in human leukemia cells.
    Rubio S, Quintana J, Eiroa JL, Triana J, Estévez F.
    Mol Carcinog; 2010 Jan 15; 49(1):32-43. PubMed ID: 19676104
    [Abstract] [Full Text] [Related]

  • 12. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun 15; 329(3):1063-70. PubMed ID: 19258520
    [Abstract] [Full Text] [Related]

  • 13. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    Sánchez Y, Amrán D, Fernández C, de Blas E, Aller P.
    Int J Cancer; 2008 Sep 01; 123(5):1205-14. PubMed ID: 18546268
    [Abstract] [Full Text] [Related]

  • 14. The anti-leukaemic activity of novel synthetic naphthoquinones against acute myeloid leukaemia: induction of cell death via the triggering of multiple signalling pathways.
    Hallak M, Win T, Shpilberg O, Bittner S, Granot Y, Levy I, Nathan I.
    Br J Haematol; 2009 Nov 01; 147(4):459-70. PubMed ID: 19747367
    [Abstract] [Full Text] [Related]

  • 15. MEK inhibition induces caspases activation, differentiation blockade and PML/RARalpha degradation in acute promyelocytic leukaemia.
    Barbarroja N, Siendones E, Torres LA, Luque MJ, Martinez JM, Dorado G, Velasco F, Torres A, López-Pedrera C.
    Br J Haematol; 2008 Jul 01; 142(1):27-35. PubMed ID: 18445086
    [Abstract] [Full Text] [Related]

  • 16. PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.
    Matsumoto E, Hatanaka M, Bohgaki M, Maeda S.
    Kobe J Med Sci; 2006 Jul 01; 52(6):181-94. PubMed ID: 17329956
    [Abstract] [Full Text] [Related]

  • 17. Diallyl trisulfide-induced G(2)-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc 25 C.
    Xiao D, Herman-Antosiewicz A, Antosiewicz J, Xiao H, Brisson M, Lazo JS, Singh SV.
    Oncogene; 2005 Sep 15; 24(41):6256-68. PubMed ID: 15940258
    [Abstract] [Full Text] [Related]

  • 18. Genistein blocks breast cancer cells in the G(2)M phase of the cell cycle.
    Cappelletti V, Fioravanti L, Miodini P, Di Fronzo G.
    J Cell Biochem; 2000 Sep 14; 79(4):594-600. PubMed ID: 10996850
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation.
    Billottet C, Banerjee L, Vanhaesebroeck B, Khwaja A.
    Cancer Res; 2009 Feb 01; 69(3):1027-36. PubMed ID: 19176369
    [Abstract] [Full Text] [Related]

  • 20. ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis.
    Yan W, Arai A, Aoki M, Ichijo H, Miura O.
    Biochem Biophys Res Commun; 2007 Apr 20; 355(4):1038-44. PubMed ID: 17331470
    [Abstract] [Full Text] [Related]

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