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Journal Abstract Search


101 related items for PubMed ID: 1903948

  • 1. Dihydroisoquinolinones: the design and synthesis of a new series of potent inhibitors of poly(ADP-ribose) polymerase.
    Suto MJ, Turner WR, Arundel-Suto CM, Werbel LM, Sebolt-Leopold JS.
    Anticancer Drug Des; 1991 May; 6(2):107-17. PubMed ID: 1903948
    [Abstract] [Full Text] [Related]

  • 2. Effect of PD 128763, a new potent inhibitor of poly(ADP-ribose) polymerase, on X-ray-induced cellular recovery processes in Chinese hamster V79 cells.
    Arundel-Suto CM, Scavone SV, Turner WR, Suto MJ, Sebolt-Leopold JS.
    Radiat Res; 1991 Jun; 126(3):367-71. PubMed ID: 1903547
    [Abstract] [Full Text] [Related]

  • 3. Poly(ADP-ribose) and the response of cells to ionizing radiation.
    Oleinick NL, Evans HH.
    Radiat Res; 1985 Jan; 101(1):29-46. PubMed ID: 3918331
    [Abstract] [Full Text] [Related]

  • 4. Inhibitors of poly(adenosine diphosphoribose) synthetase, examination of metabolic perturbations, and enhancement of radiation response in Chinese hamster cells.
    Ben-Hur E, Chen CC, Elkind MM.
    Cancer Res; 1985 May; 45(5):2123-7. PubMed ID: 2985245
    [Abstract] [Full Text] [Related]

  • 5. Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP).
    Griffin RJ, Srinivasan S, Bowman K, Calvert AH, Curtin NJ, Newell DR, Pemberton LC, Golding BT.
    J Med Chem; 1998 Dec 17; 41(26):5247-56. PubMed ID: 9857092
    [Abstract] [Full Text] [Related]

  • 6. Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone.
    Jagtap PG, Baloglu E, Southan GJ, Mabley JG, Li H, Zhou J, van Duzer J, Salzman AL, Szabó C.
    J Med Chem; 2005 Aug 11; 48(16):5100-3. PubMed ID: 16078828
    [Abstract] [Full Text] [Related]

  • 7. Poly(ADP-ribose) synthetase inhibitors increase radiation and thermal sensitivity but do not affect thermotolerance.
    Raaphorst GP, Azzam EI.
    Radiat Res; 1988 Dec 11; 116(3):442-52. PubMed ID: 3144719
    [Abstract] [Full Text] [Related]

  • 8. Radiosensitization of human fibroblasts by 3-aminobenzamide: an inhibitor of poly(ADP-ribosylation).
    Thraves P, Mossman KL, Brennan T, Dritschilo A.
    Radiat Res; 1985 Nov 11; 104(2 Pt 1):119-27. PubMed ID: 3936114
    [Abstract] [Full Text] [Related]

  • 9. Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitors.
    Branca D, Cerretani M, Jones P, Koch U, Orvieto F, Palumbi MC, Rowley M, Toniatti C, Muraglia E.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4042-5. PubMed ID: 19553107
    [Abstract] [Full Text] [Related]

  • 10. Suppression of the radiation-sensitive phenotype of hamster irs1 and irs2 strains selected for resistance to 3-aminobenzamide.
    Ganesh A, Phillips E, Thacker J, Meuth M.
    Int J Radiat Biol; 2001 May 01; 77(5):609-16. PubMed ID: 11382339
    [Abstract] [Full Text] [Related]

  • 11. Specificity of inhibitors of poly(ADP-ribose) synthesis. Effects on nucleotide metabolism in cultured cells.
    Hunting DJ, Gowans BJ, Henderson JF.
    Mol Pharmacol; 1985 Aug 01; 28(2):200-6. PubMed ID: 2991739
    [Abstract] [Full Text] [Related]

  • 12. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.
    Menear KA, Adcock C, Boulter R, Cockcroft XL, Copsey L, Cranston A, Dillon KJ, Drzewiecki J, Garman S, Gomez S, Javaid H, Kerrigan F, Knights C, Lau A, Loh VM, Matthews IT, Moore S, O'Connor MJ, Smith GC, Martin NM.
    J Med Chem; 2008 Oct 23; 51(20):6581-91. PubMed ID: 18800822
    [Abstract] [Full Text] [Related]

  • 13. Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
    Eltze T, Boer R, Wagner T, Weinbrenner S, McDonald MC, Thiemermann C, Bürkle A, Klein T.
    Mol Pharmacol; 2008 Dec 23; 74(6):1587-98. PubMed ID: 18809672
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase.
    Tikhe JG, Webber SE, Hostomsky Z, Maegley KA, Ekkers A, Li J, Yu XH, Almassy RJ, Kumpf RA, Boritzki TJ, Zhang C, Calabrese CR, Curtin NJ, Kyle S, Thomas HD, Wang LZ, Calvert AH, Golding BT, Griffin RJ, Newell DR.
    J Med Chem; 2004 Oct 21; 47(22):5467-81. PubMed ID: 15481984
    [Abstract] [Full Text] [Related]

  • 15. The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury.
    Bozlu M, Eskandari G, Cayan S, Canpolat B, Akbay E, Atik U.
    J Urol; 2003 May 21; 169(5):1870-3. PubMed ID: 12686864
    [Abstract] [Full Text] [Related]

  • 16. Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase.
    Hattori K, Kido Y, Yamamoto H, Ishida J, Iwashita A, Mihara K.
    Bioorg Med Chem Lett; 2007 Oct 15; 17(20):5577-81. PubMed ID: 17804225
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent.
    Zhu GD, Gandhi VB, Gong J, Thomas S, Luo Y, Liu X, Shi Y, Klinghofer V, Johnson EF, Frost D, Donawho C, Jarvis K, Bouska J, Marsh KC, Rosenberg SH, Giranda VL, Penning TD.
    Bioorg Med Chem Lett; 2008 Jul 15; 18(14):3955-8. PubMed ID: 18586490
    [Abstract] [Full Text] [Related]

  • 18. Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries.
    Ferraris D, Ko YS, Pahutski T, Ficco RP, Serdyuk L, Alemu C, Bradford C, Chiou T, Hoover R, Huang S, Lautar S, Liang S, Lin Q, Lu MX, Mooney M, Morgan L, Qian Y, Tran S, Williams LR, Wu QY, Zhang J, Zou Y, Kalish V.
    J Med Chem; 2003 Jul 03; 46(14):3138-51. PubMed ID: 12825952
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Miyashiro J, Woods KW, Park CH, Liu X, Shi Y, Johnson EF, Bouska JJ, Olson AM, Luo Y, Fry EH, Giranda VL, Penning TD.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4050-4. PubMed ID: 19553114
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of poly (ADP-ribose) polymerase as a protective effect of nicaraven in ionizing radiation- and ara-C-induced cell death.
    Watanabe M, Akiyama N, Sekine H, Mori M, Manome Y.
    Anticancer Res; 2006 Aug 01; 26(5A):3421-7. PubMed ID: 17094462
    [Abstract] [Full Text] [Related]


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