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373 related items for PubMed ID: 19047164

  • 1. Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue.
    Leamon CP, Reddy JA, Vetzel M, Dorton R, Westrick E, Parker N, Wang Y, Vlahov I.
    Cancer Res; 2008 Dec 01; 68(23):9839-44. PubMed ID: 19047164
    [Abstract] [Full Text] [Related]

  • 2. Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.
    Reddy JA, Westrick E, Santhapuram HK, Howard SJ, Miller ML, Vetzel M, Vlahov I, Chari RV, Goldmacher VS, Leamon CP.
    Cancer Res; 2007 Jul 01; 67(13):6376-82. PubMed ID: 17616697
    [Abstract] [Full Text] [Related]

  • 3. In vivo structural activity and optimization studies of folate-tubulysin conjugates.
    Reddy JA, Dorton R, Dawson A, Vetzel M, Parker N, Nicoson JS, Westrick E, Klein PJ, Wang Y, Vlahov IR, Leamon CP.
    Mol Pharm; 2009 Jul 01; 6(5):1518-25. PubMed ID: 19630399
    [Abstract] [Full Text] [Related]

  • 4. The therapeutic efficiency of FP-PEA/TAM67 gene complexes via folate receptor-mediated endocytosis in a xenograft mice model.
    Arote RB, Hwang SK, Lim HT, Kim TH, Jere D, Jiang HL, Kim YK, Cho MH, Cho CS.
    Biomaterials; 2010 Mar 01; 31(8):2435-45. PubMed ID: 20022105
    [Abstract] [Full Text] [Related]

  • 5. Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models.
    Gabizon A, Tzemach D, Gorin J, Mak L, Amitay Y, Shmeeda H, Zalipsky S.
    Cancer Chemother Pharmacol; 2010 May 01; 66(1):43-52. PubMed ID: 19779718
    [Abstract] [Full Text] [Related]

  • 6. Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy.
    Leamon CP, Reddy JA, Vlahov IR, Dorton R, Bloomfield A, Vetzel M, Klein PJ, Westrick E, Xu LC, Wang Y.
    Cancer Chemother Pharmacol; 2017 Jun 01; 79(6):1151-1160. PubMed ID: 28451831
    [Abstract] [Full Text] [Related]

  • 7. Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.
    Reddy JA, Dorton R, Westrick E, Dawson A, Smith T, Xu LC, Vetzel M, Kleindl P, Vlahov IR, Leamon CP.
    Cancer Res; 2007 May 01; 67(9):4434-42. PubMed ID: 17483358
    [Abstract] [Full Text] [Related]

  • 8. Impact of high and low folate diets on tissue folate receptor levels and antitumor responses toward folate-drug conjugates.
    Leamon CP, Reddy JA, Dorton R, Bloomfield A, Emsweller K, Parker N, Westrick E.
    J Pharmacol Exp Ther; 2008 Dec 01; 327(3):918-25. PubMed ID: 18791065
    [Abstract] [Full Text] [Related]

  • 9. Folate-targeted dinitrophenyl hapten immunotherapy: effect of linker chemistry on antitumor activity and allergic potential.
    Lu Y, You F, Vlahov I, Westrick E, Fan M, Low PS, Leamon CP.
    Mol Pharm; 2007 Dec 01; 4(5):695-706. PubMed ID: 17784727
    [Abstract] [Full Text] [Related]

  • 10. Isostructural folate conjugates radiolabeled with the matched pair 99mTc/188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors.
    Müller C, Schubiger PA, Schibli R.
    Nucl Med Biol; 2007 Aug 01; 34(6):595-601. PubMed ID: 17707798
    [Abstract] [Full Text] [Related]

  • 11. Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative.
    Ross TL, Honer M, Lam PY, Mindt TL, Groehn V, Schibli R, Schubiger PA, Ametamey SM.
    Bioconjug Chem; 2008 Dec 01; 19(12):2462-70. PubMed ID: 19053298
    [Abstract] [Full Text] [Related]

  • 12. Folate-targeted chemotherapy.
    Leamon CP, Reddy JA.
    Adv Drug Deliv Rev; 2004 Apr 29; 56(8):1127-41. PubMed ID: 15094211
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate.
    Leamon CP, Reddy JA, Vlahov IR, Kleindl PJ, Vetzel M, Westrick E.
    Bioconjug Chem; 2006 Apr 29; 17(5):1226-32. PubMed ID: 16984132
    [Abstract] [Full Text] [Related]

  • 14. [Folate receptor-mediated antitumor drugs].
    Zhao J, Cao SL, Zheng XL, Zhao B.
    Yao Xue Xue Bao; 2009 Feb 29; 44(2):109-14. PubMed ID: 19408677
    [Abstract] [Full Text] [Related]

  • 15. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
    Gibbs DD, Theti DS, Wood N, Green M, Raynaud F, Valenti M, Forster MD, Mitchell F, Bavetsias V, Henderson E, Jackman AL.
    Cancer Res; 2005 Dec 15; 65(24):11721-8. PubMed ID: 16357184
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic.
    Leamon CP, Reddy JA, Vlahov IR, Vetzel M, Parker N, Nicoson JS, Xu LC, Westrick E.
    Bioconjug Chem; 2005 Dec 15; 16(4):803-11. PubMed ID: 16029021
    [Abstract] [Full Text] [Related]

  • 17. Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo.
    Leamon CP, Cooper SR, Hardee GE.
    Bioconjug Chem; 2003 Dec 15; 14(4):738-47. PubMed ID: 12862426
    [Abstract] [Full Text] [Related]

  • 18. Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of (99m)Tc-EC20 in xenografted and syngeneic tumor-bearing mice.
    Müller C, Reddy JA, Leamon CP, Schibli R.
    Mol Pharm; 2010 Apr 05; 7(2):597-604. PubMed ID: 20199053
    [Abstract] [Full Text] [Related]

  • 19. Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts.
    Yoshizawa T, Hattori Y, Hakoshima M, Koga K, Maitani Y.
    Eur J Pharm Biopharm; 2008 Nov 05; 70(3):718-25. PubMed ID: 18647651
    [Abstract] [Full Text] [Related]

  • 20. Folate receptor specific anti-tumor activity of folate-mitomycin conjugates.
    Reddy JA, Westrick E, Vlahov I, Howard SJ, Santhapuram HK, Leamon CP.
    Cancer Chemother Pharmacol; 2006 Aug 05; 58(2):229-36. PubMed ID: 16331500
    [Abstract] [Full Text] [Related]

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