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Journal Abstract Search


255 related items for PubMed ID: 1905016

  • 1. Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.
    Umar A, Schweitzer PA, Levy NS, Gearhart JD, Gearhart PJ.
    Proc Natl Acad Sci U S A; 1991 Jun 01; 88(11):4902-6. PubMed ID: 1905016
    [Abstract] [Full Text] [Related]

  • 2. Variable kappa gene rearrangement in lymphoproliferative disorders: an analysis of V kappa gene usage, VJ joining and somatic mutation.
    Cannell PK, Amlot P, Attard M, Hoffbrand AV, Foroni L.
    Leukemia; 1994 Jul 01; 8(7):1139-45. PubMed ID: 8035605
    [Abstract] [Full Text] [Related]

  • 3. Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.
    Lebecque SG, Gearhart PJ.
    J Exp Med; 1990 Dec 01; 172(6):1717-27. PubMed ID: 2258702
    [Abstract] [Full Text] [Related]

  • 4. Position of the rearranged V kappa and its 5' flanking sequences determines the location of somatic mutations in the J kappa locus.
    Weber JS, Berry J, Manser T, Claflin JL.
    J Immunol; 1991 May 15; 146(10):3652-5. PubMed ID: 1902859
    [Abstract] [Full Text] [Related]

  • 5. Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus.
    Lawler AM, Kearney JF, Kuehl M, Gearhart PJ.
    Proc Natl Acad Sci U S A; 1989 Sep 15; 86(17):6744-7. PubMed ID: 2505260
    [Abstract] [Full Text] [Related]

  • 6. Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.
    O'Brien RL, Brinster RL, Storb U.
    Nature; 1989 Sep 15; 326(6111):405-9. PubMed ID: 3104790
    [Abstract] [Full Text] [Related]

  • 7. V gene rearrangement is required to fully activate the hypermutation mechanism in B cells.
    Roes J, Hüppi K, Rajewsky K, Sablitzky F.
    J Immunol; 1989 Feb 01; 142(3):1022-6. PubMed ID: 2492327
    [Abstract] [Full Text] [Related]

  • 8. High-level rearrangement and transcription of yeast artificial chromosome-based mouse Ig kappa transgenes containing distal regions of the contig.
    Li S, Hammer RE, George-Raizen JB, Meyers KC, Garrard WT.
    J Immunol; 2000 Jan 15; 164(2):812-24. PubMed ID: 10623827
    [Abstract] [Full Text] [Related]

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  • 10. B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain.
    Pewzner-Jung Y, Friedmann D, Sonoda E, Jung S, Rajewsky K, Eilat D.
    J Immunol; 1998 Nov 01; 161(9):4634-45. PubMed ID: 9794392
    [Abstract] [Full Text] [Related]

  • 11. Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes.
    Rogerson BJ.
    Mol Immunol; 1994 Feb 01; 31(2):83-98. PubMed ID: 8309480
    [Abstract] [Full Text] [Related]

  • 12. Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts.
    Tuaillon N, Taylor LD, Lonberg N, Tucker PW, Capra JD.
    Proc Natl Acad Sci U S A; 1993 Apr 15; 90(8):3720-4. PubMed ID: 8475122
    [Abstract] [Full Text] [Related]

  • 13. B lineage-restricted rearrangement of a human Ig kappa transgene.
    Cavelier P, Nato F, Coquilleau I, Rolink A, Rougeon F, Goodhardt M.
    Eur J Immunol; 1997 Jul 15; 27(7):1626-31. PubMed ID: 9247570
    [Abstract] [Full Text] [Related]

  • 14. Promoter-associated displacement of hypermutations.
    Wu P, Claflin L.
    Int Immunol; 1998 Aug 15; 10(8):1131-8. PubMed ID: 9723699
    [Abstract] [Full Text] [Related]

  • 15. Somatic mutations in the Ig variable region genes and expression of novel Cmu-germline transcripts in a B-lymphoma cell line ("Farage") not producing Ig polypeptide chains.
    Hochberg M, Gabay C, Laskov R.
    Leuk Lymphoma; 1998 Aug 15; 30(5-6):637-49. PubMed ID: 9711926
    [Abstract] [Full Text] [Related]

  • 16. Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.
    Sharpe MJ, Milstein C, Jarvis JM, Neuberger MS.
    EMBO J; 1991 Aug 15; 10(8):2139-45. PubMed ID: 1905999
    [Abstract] [Full Text] [Related]

  • 17. Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription.
    Martin D, Huang RQ, LeBien T, Van Ness B.
    J Exp Med; 1991 Mar 01; 173(3):639-45. PubMed ID: 1900078
    [Abstract] [Full Text] [Related]

  • 18. Analysis of hypermutation in immunoglobulin heavy chain passenger transgenes.
    Johnston JM, Ihyer SR, Smith RS, Tai KF, Farmer T, Korsmeyer SJ, Nadon NL, Carroll WL.
    Eur J Immunol; 1996 May 01; 26(5):1058-62. PubMed ID: 8647167
    [Abstract] [Full Text] [Related]

  • 19. Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations.
    Adderson EE, Shackelford PG, Insel RA, Quinn A, Wilson PM, Carroll WL.
    J Clin Invest; 1992 Mar 01; 89(3):729-38. PubMed ID: 1541667
    [Abstract] [Full Text] [Related]

  • 20. The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron.
    Rada C, González-Fernández A, Jarvis JM, Milstein C.
    Eur J Immunol; 1994 Jun 01; 24(6):1453-7. PubMed ID: 8206104
    [Abstract] [Full Text] [Related]


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