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131 related items for PubMed ID: 19053745

  • 1. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease.
    Deraos G, Chatzantoni K, Matsoukas MT, Tselios T, Deraos S, Katsara M, Papathanasopoulos P, Vynios D, Apostolopoulos V, Mouzaki A, Matsoukas J.
    J Med Chem; 2008 Dec 25; 51(24):7834-42. PubMed ID: 19053745
    [Abstract] [Full Text] [Related]

  • 2. Design of novel cyclic altered peptide ligands of myelin basic protein MBP83-99 that modulate immune responses in SJL/J mice.
    Katsara M, Deraos G, Tselios T, Matsoukas J, Apostolopoulos V.
    J Med Chem; 2008 Jul 10; 51(13):3971-8. PubMed ID: 18563891
    [Abstract] [Full Text] [Related]

  • 3. Cryoelectron microscopy of protein-lipid complexes of human myelin basic protein charge isomers differing in degree of citrullination.
    Beniac DR, Wood DD, Palaniyar N, Ottensmeyer FP, Moscarello MA, Harauz G.
    J Struct Biol; 2000 Feb 10; 129(1):80-95. PubMed ID: 10675299
    [Abstract] [Full Text] [Related]

  • 4. Design and synthesis of a cyclic double mutant peptide (cyclo(87-99)[A91,A96]MBP87-99) induces altered responses in mice after conjugation to mannan: implications in the immunotherapy of multiple sclerosis.
    Katsara M, Deraos G, Tselios T, Matsoukas MT, Friligou I, Matsoukas J, Apostolopoulos V.
    J Med Chem; 2009 Jan 08; 52(1):214-8. PubMed ID: 19072222
    [Abstract] [Full Text] [Related]

  • 5. Highly deiminated isoform of myelin basic protein from multiple sclerosis brain causes fragmentation of lipid vesicles.
    Boggs JM, Rangaraj G, Koshy KM, Ackerley C, Wood DD, Moscarello MA.
    J Neurosci Res; 1999 Aug 15; 57(4):529-35. PubMed ID: 10440902
    [Abstract] [Full Text] [Related]

  • 6. Properties of myelin altered peptide ligand cyclo(87-99)(Ala91,Ala96)MBP87-99 render it a promising drug lead for immunotherapy of multiple sclerosis.
    Deraos G, Rodi M, Kalbacher H, Chatzantoni K, Karagiannis F, Synodinos L, Plotas P, Papalois A, Dimisianos N, Papathanasopoulos P, Gatos D, Tselios T, Apostolopoulos V, Mouzaki A, Matsoukas J.
    Eur J Med Chem; 2015 Aug 28; 101():13-23. PubMed ID: 26112377
    [Abstract] [Full Text] [Related]

  • 7. Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS.
    Musse AA, Harauz G.
    Int Rev Neurobiol; 2007 Aug 28; 79():149-72. PubMed ID: 17531841
    [Abstract] [Full Text] [Related]

  • 8. Targeted analysis of protein citrullination using chemical modification and tandem mass spectrometry.
    Stensland M, Holm A, Kiehne A, Fleckenstein B.
    Rapid Commun Mass Spectrom; 2009 Sep 28; 23(17):2754-62. PubMed ID: 19639564
    [Abstract] [Full Text] [Related]

  • 9. Dendritic cells loaded with apoptotic oligodendrocytes as a source of myelin T-cell epitopes in multiple sclerosis.
    Meloni F, Accapezzato D, Agresti C, Aloisi F, Ristori G, Salvetti M, Furlan R, Martino G, Barnaba V, Paroli M.
    Clin Immunol; 2008 Nov 28; 129(2):286-94. PubMed ID: 18753013
    [Abstract] [Full Text] [Related]

  • 10. Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis.
    Mastronardi FG, Mak B, Ackerley CA, Roots BI, Moscarello MA.
    J Clin Invest; 1996 Jan 15; 97(2):349-58. PubMed ID: 8567954
    [Abstract] [Full Text] [Related]

  • 11. Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.
    Matsoukas J, Apostolopoulos V, Kalbacher H, Papini AM, Tselios T, Chatzantoni K, Biagioli T, Lolli F, Deraos S, Papathanassopoulos P, Troganis A, Mantzourani E, Mavromoustakos T, Mouzaki A.
    J Med Chem; 2005 Mar 10; 48(5):1470-80. PubMed ID: 15743189
    [Abstract] [Full Text] [Related]

  • 12. Marburg's variant of multiple sclerosis correlates with a less compact structure of myelin basic protein.
    Beniac DR, Wood DD, Palaniyar N, Ottensmeyer FP, Moscarello MA, Harauz G.
    Mol Cell Biol Res Commun; 1999 Apr 10; 1(1):48-51. PubMed ID: 10329477
    [Abstract] [Full Text] [Related]

  • 13. Rapid release and unusual stability of immunodominant peptide 45-89 from citrullinated myelin basic protein.
    Cao L, Goodin R, Wood D, Moscarello MA, Whitaker JN.
    Biochemistry; 1999 May 11; 38(19):6157-63. PubMed ID: 10320343
    [Abstract] [Full Text] [Related]

  • 14. IgG reactivity against citrullinated myelin basic protein in multiple sclerosis.
    de Seze J, Dubucquoi S, Lefranc D, Virecoulon F, Nuez I, Dutoit V, Vermersch P, Prin L.
    J Neuroimmunol; 2001 Jul 02; 117(1-2):149-55. PubMed ID: 11431015
    [Abstract] [Full Text] [Related]

  • 15. Cyclic citrullinated MBP87-99 peptide stimulates T cell responses: Implications in triggering disease.
    Apostolopoulos V, Deraos G, Matsoukas MT, Day S, Stojanovska L, Tselios T, Androutsou ME, Matsoukas J.
    Bioorg Med Chem; 2017 Jan 15; 25(2):528-538. PubMed ID: 27908754
    [Abstract] [Full Text] [Related]

  • 16. A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99.
    Mantzourani ED, Tselios TV, Grdadolnik SG, Brancale A, Platts JA, Matsoukas JM, Mavromoustakos TM.
    J Mol Graph Model; 2006 Sep 15; 25(1):17-29. PubMed ID: 16310386
    [Abstract] [Full Text] [Related]

  • 17. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response.
    Mantzourani ED, Platts JA, Brancale A, Mavromoustakos TM, Tselios TV.
    J Mol Graph Model; 2007 Sep 15; 26(2):471-81. PubMed ID: 17392002
    [Abstract] [Full Text] [Related]

  • 18. Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry.
    D'Souza CA, Wood DD, She YM, Moscarello MA.
    Biochemistry; 2005 Sep 27; 44(38):12905-13. PubMed ID: 16171406
    [Abstract] [Full Text] [Related]

  • 19. Antibodies against a class II HLA-peptide complex raised by active immunization of mice with antigen mimicking peptides.
    Dam-Tuxen R, Riise E.
    Scand J Immunol; 2009 Aug 27; 70(2):93-100. PubMed ID: 19630914
    [Abstract] [Full Text] [Related]

  • 20. Myelin in multiple sclerosis is developmentally immature.
    Moscarello MA, Wood DD, Ackerley C, Boulias C.
    J Clin Invest; 1994 Jul 27; 94(1):146-54. PubMed ID: 7518827
    [Abstract] [Full Text] [Related]

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