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Journal Abstract Search

335 related items for PubMed ID: 19053785

  • 1.
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  • 2. Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening.
    Turk S, Kovac A, Boniface A, Bostock JM, Chopra I, Blanot D, Gobec S.
    Bioorg Med Chem; 2009 Mar 01; 17(5):1884-9. PubMed ID: 19223185
    [Abstract] [Full Text] [Related]

  • 3. Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.
    Perdih A, Kovac A, Wolber G, Blanot D, Gobec S, Solmajer T.
    Bioorg Med Chem Lett; 2009 May 15; 19(10):2668-73. PubMed ID: 19369074
    [Abstract] [Full Text] [Related]

  • 4. D-Alanine:D-alanine ligase as a new target for the flavonoids quercetin and apigenin.
    Wu D, Kong Y, Han C, Chen J, Hu L, Jiang H, Shen X.
    Int J Antimicrob Agents; 2008 Nov 15; 32(5):421-6. PubMed ID: 18774266
    [Abstract] [Full Text] [Related]

  • 5. Discovery of VHR phosphatase inhibitors with micromolar activity based on structure-based virtual screening.
    Park H, Jung SK, Jeong DG, Ryu SE, Kim SJ.
    ChemMedChem; 2008 Jun 15; 3(6):877-80. PubMed ID: 18236492
    [No Abstract] [Full Text] [Related]

  • 6. Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.
    Yi Mok N, Chadwick J, Kellett KA, Hooper NM, Johnson AP, Fishwick CW.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6770-4. PubMed ID: 19854048
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.
    Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O'Neill AJ, Mengin-Lecreulx D, Blanot D, Gobec S.
    Eur J Med Chem; 2013 Aug 01; 66():32-45. PubMed ID: 23786712
    [Abstract] [Full Text] [Related]

  • 8. Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).
    Tomasić T, Zidar N, Sink R, Kovac A, Blanot D, Contreras-Martel C, Dessen A, Müller-Premru M, Zega A, Gobec S, Kikelj D, Masic LP.
    J Med Chem; 2011 Jul 14; 54(13):4600-10. PubMed ID: 21591605
    [Abstract] [Full Text] [Related]

  • 9. Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori.
    Wu D, Zhang L, Kong Y, Du J, Chen S, Chen J, Ding J, Jiang H, Shen X.
    Proteins; 2008 Sep 14; 72(4):1148-60. PubMed ID: 18320587
    [Abstract] [Full Text] [Related]

  • 10. Gain of D-alanyl-D-lactate or D-lactyl-D-alanine synthetase activities in three active-site mutants of the Escherichia coli D-alanyl-D-alanine ligase B.
    Park IS, Lin CH, Walsh CT.
    Biochemistry; 1996 Aug 13; 35(32):10464-71. PubMed ID: 8756703
    [Abstract] [Full Text] [Related]

  • 11. Characterization of Chlamydia MurC-Ddl, a fusion protein exhibiting D-alanyl-D-alanine ligase activity involved in peptidoglycan synthesis and D-cycloserine sensitivity.
    McCoy AJ, Maurelli AT.
    Mol Microbiol; 2005 Jul 13; 57(1):41-52. PubMed ID: 15948948
    [Abstract] [Full Text] [Related]

  • 12. Modeling of Enterococcus faecalis D-alanine:D-alanine ligase: structure-based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutants.
    Prévost M, Van Belle D, Tulkens PM, Courvalin P, Van Bambeke F.
    J Mol Microbiol Biotechnol; 2000 Jul 13; 2(3):321-30. PubMed ID: 10937441
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.
    Strancar K, Blanot D, Gobec S.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):343-8. PubMed ID: 16271472
    [Abstract] [Full Text] [Related]

  • 14. Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.
    Humljan J, Kotnik M, Contreras-Martel C, Blanot D, Urleb U, Dessen A, Solmajer T, Gobec S.
    J Med Chem; 2008 Dec 11; 51(23):7486-94. PubMed ID: 19007109
    [Abstract] [Full Text] [Related]

  • 15. 6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.
    Škedelj V, Arsovska E, Tomašić T, Kroflič A, Hodnik V, Hrast M, Bešter-Rogač M, Anderluh G, Gobec S, Bostock J, Chopra I, O'Neill AJ, Randall C, Zega A.
    PLoS One; 2012 Dec 11; 7(8):e39922. PubMed ID: 22876277
    [Abstract] [Full Text] [Related]

  • 16. Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening.
    Park H, Bahn YJ, Jung SK, Jeong DG, Lee SH, Seo I, Yoon TS, Kim SJ, Ryu SE.
    J Med Chem; 2008 Sep 25; 51(18):5533-41. PubMed ID: 18714978
    [Abstract] [Full Text] [Related]

  • 17. Function of the D-alanine:D-alanine ligase lid loop: a molecular modeling and bioactivity study.
    Hrast M, Vehar B, Turk S, Konc J, Gobec S, Janežič D.
    J Med Chem; 2012 Aug 09; 55(15):6849-56. PubMed ID: 22803830
    [Abstract] [Full Text] [Related]

  • 18. MurD enzymes from different bacteria: evaluation of inhibitors.
    Barreteau H, Sosič I, Turk S, Humljan J, Tomašić T, Zidar N, Hervé M, Boniface A, Peterlin-Mašič L, Kikelj D, Mengin-Lecreulx D, Gobec S, Blanot D.
    Biochem Pharmacol; 2012 Sep 01; 84(5):625-32. PubMed ID: 22705647
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