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Journal Abstract Search

418 related items for PubMed ID: 19073193

  • 1. Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity.
    Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M.
    J Mol Biol; 2009 Feb 06; 385(5):1556-67. PubMed ID: 19073193
    [Abstract] [Full Text] [Related]

  • 2. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
    Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ.
    Biochemistry; 2005 May 03; 44(17):6513-25. PubMed ID: 15850385
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  • 5. Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.
    Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E.
    Chemistry; 2011 Feb 25; 17(9):2752-62. PubMed ID: 21274957
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  • 6. The proteolytic activity of insulin-degrading enzyme: a mass spectrometry study.
    Grasso G, Rizzarelli E, Spoto G.
    J Mass Spectrom; 2009 May 25; 44(5):735-41. PubMed ID: 19127548
    [Abstract] [Full Text] [Related]

  • 7. Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
    Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR.
    J Neurochem; 2009 Mar 25; 108(5):1198-207. PubMed ID: 19141082
    [Abstract] [Full Text] [Related]

  • 8. Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin.
    Tundo GR, Di Muzio E, Ciaccio C, Sbardella D, Di Pierro D, Polticelli F, Coletta M, Marini S.
    FEBS J; 2016 Oct 25; 283(20):3755-3770. PubMed ID: 27579517
    [Abstract] [Full Text] [Related]

  • 9. Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide.
    Tõugu V, Karafin A, Palumaa P.
    J Neurochem; 2008 Mar 25; 104(5):1249-59. PubMed ID: 18289347
    [Abstract] [Full Text] [Related]

  • 10. Zinc binding to Alzheimer's Abeta(1-16) peptide results in stable soluble complex.
    Kozin SA, Zirah S, Rebuffat S, Hoa GH, Debey P.
    Biochem Biophys Res Commun; 2001 Jul 27; 285(4):959-64. PubMed ID: 11467845
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  • 11. A highly sensitive peptide substrate for detecting two Aß-degrading enzymes: neprilysin and insulin-degrading enzyme.
    Chen PT, Liao TY, Hu CJ, Wu ST, Wang SS, Chen RP.
    J Neurosci Methods; 2010 Jun 30; 190(1):57-62. PubMed ID: 20435063
    [Abstract] [Full Text] [Related]

  • 12. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
    Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA.
    Neurobiol Aging; 2005 Jun 30; 26(6):795-802. PubMed ID: 15718037
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  • 13. Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease.
    Liu ST, Howlett G, Barrow CJ.
    Biochemistry; 1999 Jul 20; 38(29):9373-8. PubMed ID: 10413512
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  • 14. Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
    Turner RT, Hong L, Koelsch G, Ghosh AK, Tang J.
    Biochemistry; 2005 Jan 11; 44(1):105-12. PubMed ID: 15628850
    [Abstract] [Full Text] [Related]

  • 15. Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation.
    Cordes CM, Bennett RG, Siford GL, Hamel FG.
    Biochem Pharmacol; 2009 Mar 15; 77(6):1064-73. PubMed ID: 19154729
    [Abstract] [Full Text] [Related]

  • 16. The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Toropygin IY, Kugaevskaya EV, Mirgorodskaya OA, Elisseeva YE, Kozmin YP, Popov IA, Nikolaev EN, Makarov AA, Kozin SA.
    Rapid Commun Mass Spectrom; 2008 Mar 15; 22(2):231-9. PubMed ID: 18085519
    [Abstract] [Full Text] [Related]

  • 17. Binding epitopes and interaction structure of the neuroprotective protease inhibitor cystatin C with beta-amyloid revealed by proteolytic excision mass spectrometry and molecular docking simulation.
    Juszczyk P, Paraschiv G, Szymanska A, Kolodziejczyk AS, Rodziewicz-Motowidlo S, Grzonka Z, Przybylski M.
    J Med Chem; 2009 Apr 23; 52(8):2420-8. PubMed ID: 19317448
    [Abstract] [Full Text] [Related]

  • 18. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.
    Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ.
    J Mol Biol; 2010 Jan 15; 395(2):430-43. PubMed ID: 19896952
    [Abstract] [Full Text] [Related]

  • 19. Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention.
    Eckman EA, Eckman CB.
    Biochem Soc Trans; 2005 Nov 15; 33(Pt 5):1101-5. PubMed ID: 16246055
    [Abstract] [Full Text] [Related]

  • 20. Immunocapture-based fluorometric assay for the measurement of insulin-degrading enzyme activity in brain tissue homogenates.
    Miners JS, Kehoe PG, Love S.
    J Neurosci Methods; 2008 Mar 30; 169(1):177-81. PubMed ID: 18221786
    [Abstract] [Full Text] [Related]

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