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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

158 related items for PubMed ID: 19081720

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  • 3. Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.
    Evindar G, Bernier SG, Doyle E, Kavarana MJ, Satz AL, Lorusso J, Blanchette HS, Saha AK, Hannig G, Morgan BA, Westlin WF.
    Bioorg Med Chem Lett; 2010 Apr 15; 20(8):2520-4. PubMed ID: 20304639
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  • 6. Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists.
    Clemens JJ, Davis MD, Lynch KR, Macdonald TL.
    Bioorg Med Chem Lett; 2004 Oct 04; 14(19):4903-6. PubMed ID: 15341948
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  • 7. A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.
    Hale JJ, Lynch CL, Neway W, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Parent SA, Chrebet G, Bergstrom J, Card D, Ferrer M, Hodder P, Strulovici B, Rosen H, Mandala S.
    J Med Chem; 2004 Dec 30; 47(27):6662-5. PubMed ID: 15615513
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  • 8. Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors.
    Yan L, Hale JJ, Lynch CL, Budhu R, Gentry A, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Rosen H, Mandala SM.
    Bioorg Med Chem Lett; 2004 Oct 04; 14(19):4861-6. PubMed ID: 15341940
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  • 9. Discovery of imidazole carboxamides as potent and selective CCK1R agonists.
    Zhu C, Hansen AR, Bateman T, Chen Z, Holt TG, Hubert JA, Karanam BV, Lee SJ, Pan J, Qian S, Reddy VB, Reitman ML, Strack AM, Tong V, Weingarth DT, Wolff MS, MacNeil DJ, Weber AE, Duffy JL, Edmondson SD.
    Bioorg Med Chem Lett; 2008 Aug 01; 18(15):4393-6. PubMed ID: 18614364
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  • 12. 2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors.
    Yan L, Budhu R, Huo P, Lynch CL, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Mandala SM.
    Bioorg Med Chem Lett; 2006 Jul 01; 16(13):3564-8. PubMed ID: 16621543
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  • 13. Discovery of a novel class of zwitterionic, potent, selective and orally active S1P₁ direct agonists.
    Aguilar N, Mir M, Grima PM, López M, Segarra V, Esteban L, Moreno I, Godessart N, Tarrasón G, Domenech T, Vilella D, Armengol C, Córdoba M, Sabaté M, Casals D, Domínguez M.
    Bioorg Med Chem Lett; 2012 Dec 15; 22(24):7672-6. PubMed ID: 23141913
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  • 14. Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes.
    Yan L, Huo P, Doherty G, Toth L, Hale JJ, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Bergstrom J, Card D, Quackenbush E, Wickham A, Mandala SM.
    Bioorg Med Chem Lett; 2006 Jul 15; 16(14):3679-83. PubMed ID: 16697189
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  • 16. Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors.
    Foss FW, Clemens JJ, Davis MD, Snyder AH, Zigler MA, Lynch KR, Macdonald TL.
    Bioorg Med Chem Lett; 2005 Oct 15; 15(20):4470-4. PubMed ID: 16125386
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  • 18. Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P(1)) receptor agonists.
    Zécri FJ, Albert R, Landrum G, Hinterding K, Cooke NG, Guerini D, Streiff M, Bruns C, Nuesslein-Hildesheim B.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):35-7. PubMed ID: 19954976
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  • 19. The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists.
    Hale JJ, Doherty G, Toth L, Li Z, Mills SG, Hajdu R, Ann Keohane C, Rosenbach M, Milligan J, Shei GJ, Chrebet G, Bergstrom J, Card D, Rosen H, Mandala S.
    Bioorg Med Chem Lett; 2004 Jul 05; 14(13):3495-9. PubMed ID: 15177460
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  • 20. Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators.
    Chae E, Shin YJ, Ryu EJ, Ji MK, Ryune Cho N, Lee KH, Jeong HJ, Kim SJ, Choi Y, Seok Oh K, Park CE, Soo Yoon Y.
    Bioorg Med Chem Lett; 2013 Apr 01; 23(7):2134-9. PubMed ID: 23434029
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