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488 related items for PubMed ID: 19095969

  • 1. Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
    Yagi K, Kitazato KT, Uno M, Tada Y, Kinouchi T, Shimada K, Nagahiro S.
    Stroke; 2009 Feb; 40(2):626-31. PubMed ID: 19095969
    [Abstract] [Full Text] [Related]

  • 2. Mechanistic insight into neurotoxicity of tissue plasminogen activator-induced thrombolysis products in a rat intraluminal middle cerebral artery occlusion model.
    Oka F, Fujisawa H, Nomura S, Kajiwara K, Kato S, Fujii M, Izuma H, Uozumi K, Gondo T, Suzuki M.
    J Neurotrauma; 2009 Sep; 26(9):1577-84. PubMed ID: 19275467
    [Abstract] [Full Text] [Related]

  • 3. Extension of ischemic therapeutic time window by a free radical scavenger, Edaravone, reperfused with tPA in rat brain.
    Zhang W, Sato K, Hayashi T, Omori N, Nagano I, Kato S, Horiuchi S, Abe K.
    Neurol Res; 2004 Apr; 26(3):342-8. PubMed ID: 15142331
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  • 4. Combination of reactive oxygen species and tissue-type plasminogen activator enhances the induction of gelatinase B in brain endothelial cells.
    Harada K, Suzuki Y, Yamakawa K, Kawakami J, Umemura K.
    Int J Neurosci; 2012 Feb; 122(2):53-9. PubMed ID: 21919816
    [Abstract] [Full Text] [Related]

  • 5. Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion.
    Pfefferkorn T, Rosenberg GA.
    Stroke; 2003 Aug; 34(8):2025-30. PubMed ID: 12855824
    [Abstract] [Full Text] [Related]

  • 6. Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats.
    Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Namioka T, Namioka A, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O.
    J Neurosurg; 2017 Oct; 127(4):917-926. PubMed ID: 28059661
    [Abstract] [Full Text] [Related]

  • 7. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia.
    Okamura K, Tsubokawa T, Johshita H, Miyazaki H, Shiokawa Y.
    Neurol Res; 2014 Jan; 36(1):65-9. PubMed ID: 24074041
    [Abstract] [Full Text] [Related]

  • 8. Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury.
    Zhang P, Li W, Li L, Wang N, Li X, Gao M, Zheng J, Lei S, Chen X, Lu H, Liu Y.
    Neuroscience; 2012 Jan 10; 201():297-306. PubMed ID: 22116052
    [Abstract] [Full Text] [Related]

  • 9. Involvement of thrombolysis in recombinant tissue plasminogen activator-induced cerebral hemorrhages and effect on infarct volume and postischemic endothelial function.
    Gautier S, Petrault O, Gele P, Laprais M, Bastide M, Bauters A, Deplanque D, Jude B, Caron J, Bordet R.
    Stroke; 2003 Dec 10; 34(12):2975-9. PubMed ID: 14615621
    [Abstract] [Full Text] [Related]

  • 10. Effects of edaravone, a free radical scavenger, on circulating levels of MMP-9 and hemorrhagic transformation in patients with intravenous thrombolysis using low-dose alteplase.
    Tsuruoka A, Atsumi C, Mizukami H, Imai T, Hagiwara Y, Hasegawa Y.
    J Stroke Cerebrovasc Dis; 2014 Dec 10; 23(10):2894-2899. PubMed ID: 25282183
    [Abstract] [Full Text] [Related]

  • 11. Free radical scavenger edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage.
    Lukic-Panin V, Deguchi K, Yamashita T, Shang J, Zhang X, Tian F, Liu N, Kawai H, Matsuura T, Abe K.
    Curr Neurovasc Res; 2010 Nov 10; 7(4):319-29. PubMed ID: 20854248
    [Abstract] [Full Text] [Related]

  • 12. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
    Zhang N, Komine-Kobayashi M, Tanaka R, Liu M, Mizuno Y, Urabe T.
    Stroke; 2005 Oct 10; 36(10):2220-5. PubMed ID: 16166574
    [Abstract] [Full Text] [Related]

  • 13. Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage.
    Nakamura T, Kuroda Y, Yamashita S, Zhang X, Miyamoto O, Tamiya T, Nagao S, Xi G, Keep RF, Itano T.
    Stroke; 2008 Feb 10; 39(2):463-9. PubMed ID: 18096835
    [Abstract] [Full Text] [Related]

  • 14. Modifying neurorepair and neuroregenerative factors with tPA and edaravone after transient middle cerebral artery occlusion in rat brain.
    Deguchi K, Miyazaki K, Tian F, Liu N, Liu W, Kawai H, Omote Y, Kono S, Yunoki T, Deguchi S, Abe K.
    Brain Res; 2012 Feb 03; 1436():168-77. PubMed ID: 22221736
    [Abstract] [Full Text] [Related]

  • 15. Effects of edaravone, the free radical scavenger, on outcomes in acute cerebral infarction patients treated with ultra-early thrombolysis of recombinant tissue plasminogen activator.
    Lee XR, Xiang GL.
    Clin Neurol Neurosurg; 2018 Apr 03; 167():157-161. PubMed ID: 29501045
    [Abstract] [Full Text] [Related]

  • 16. Combination drug therapy using edaravone and Daio-Orengedoku-to after transient focal ischemia in rats.
    Cho KH, Oh JK, Jang YS, Jung JW, Oh HR, Park EK, Kim DH, Moon SK, Kim DH, Ryu JH.
    Methods Find Exp Clin Pharmacol; 2008 Apr 03; 30(6):443-50. PubMed ID: 18850045
    [Abstract] [Full Text] [Related]

  • 17. Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
    Hung YC, Chen TY, Lee EJ, Chen WL, Huang SY, Lee WT, Lee MY, Chen HY, Wu TS.
    J Pineal Res; 2008 Nov 03; 45(4):459-67. PubMed ID: 18624955
    [Abstract] [Full Text] [Related]

  • 18. Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia.
    Deguchi K, Liu N, Liu W, Omote Y, Kono S, Yunoki T, Deguchi S, Yamashita T, Ikeda Y, Abe K.
    J Neurosci Res; 2014 Nov 03; 92(11):1509-19. PubMed ID: 24938625
    [Abstract] [Full Text] [Related]

  • 19. Neuroprotective effects of the free radical scavenger Edaravone (MCI-186) in mice permanent focal brain ischemia.
    Shichinohe H, Kuroda S, Yasuda H, Ishikawa T, Iwai M, Horiuchi M, Iwasaki Y.
    Brain Res; 2004 Dec 17; 1029(2):200-6. PubMed ID: 15542075
    [Abstract] [Full Text] [Related]

  • 20. A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion.
    Miyamoto N, Pham LD, Maki T, Liang AC, Arai K.
    Neurosci Lett; 2014 Jun 24; 573():40-45. PubMed ID: 24820542
    [Abstract] [Full Text] [Related]

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