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Journal Abstract Search

101 related items for PubMed ID: 19096133

  • 1. A genetic fusion GDNF-C fragment of tetanus toxin prolongs survival in a symptomatic mouse ALS model.
    Ciriza J, Moreno-Igoa M, Calvo AC, Yague G, Palacio J, Miana-Mena FJ, Muñoz MJ, Zaragoza P, Brûlet P, Osta R.
    Restor Neurol Neurosci; 2008; 26(6):459-65. PubMed ID: 19096133
    [Abstract] [Full Text] [Related]

  • 2. Non-viral gene delivery of the GDNF, either alone or fused to the C-fragment of tetanus toxin protein, prolongs survival in a mouse ALS model.
    Moreno-Igoa M, Calvo AC, Ciriza J, Muñoz MJ, Zaragoza P, Osta R.
    Restor Neurol Neurosci; 2012; 30(1):69-80. PubMed ID: 22124037
    [Abstract] [Full Text] [Related]

  • 3. A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice.
    Larsen KE, Benn SC, Ay I, Chian RJ, Celia SA, Remington MP, Bejarano M, Liu M, Ross J, Carmillo P, Sah D, Phillips KA, Sulzer D, Pepinsky RB, Fishman PS, Brown RH, Francis JW.
    Brain Res; 2006 Nov 20; 1120(1):1-12. PubMed ID: 17020749
    [Abstract] [Full Text] [Related]

  • 4. IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.
    Chian RJ, Li J, Ay I, Celia SA, Kashi BB, Tamrazian E, Matthews JC, Bronson RT, Rossomando A, Pepinsky RB, Fishman PS, Brown RH, Francis JW.
    Brain Res; 2009 Sep 01; 1287():1-19. PubMed ID: 19563785
    [Abstract] [Full Text] [Related]

  • 5. Lack of a synergistic effect of a non-viral ALS gene therapy based on BDNF and a TTC fusion molecule.
    Calvo AC, Moreno-Igoa M, Mancuso R, Manzano R, Oliván S, Muñoz MJ, Penas C, Zaragoza P, Navarro X, Osta R.
    Orphanet J Rare Dis; 2011 Mar 21; 6():10. PubMed ID: 21418619
    [Abstract] [Full Text] [Related]

  • 6. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
    Wang LJ, Lu YY, Muramatsu S, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Matsushita T, Hanazono Y, Kume A, Nagatsu T, Ozawa K, Nakano I.
    J Neurosci; 2002 Aug 15; 22(16):6920-8. PubMed ID: 12177190
    [Abstract] [Full Text] [Related]

  • 7. Insect GDNF:TTC fusion protein improves delivery of GDNF to mouse CNS.
    Li J, Chian RJ, Ay I, Kashi BB, Celia SA, Tamrazian E, Pepinsky RB, Fishman PS, Brown RH, Francis JW.
    Biochem Biophys Res Commun; 2009 Dec 18; 390(3):947-51. PubMed ID: 19852934
    [Abstract] [Full Text] [Related]

  • 8. Recombinant GDNF: tetanus toxin fragment C fusion protein produced from insect cells.
    Li J, Chian RJ, Ay I, Celia SA, Kashi BB, Tamrazian E, Matthews JC, Remington MP, Pepinsky RB, Fishman PS, Brown RH, Francis JW.
    Biochem Biophys Res Commun; 2009 Jul 31; 385(3):380-4. PubMed ID: 19465006
    [Abstract] [Full Text] [Related]

  • 9. Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.
    Li W, Brakefield D, Pan Y, Hunter D, Myckatyn TM, Parsadanian A.
    Exp Neurol; 2007 Feb 31; 203(2):457-71. PubMed ID: 17034790
    [Abstract] [Full Text] [Related]

  • 10. Glial cell line-derived neurotrophic factor protein prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis.
    Manabe Y, Nagano I, Gazi MS, Murakami T, Shiote M, Shoji M, Kitagawa H, Abe K.
    Neurol Res; 2003 Mar 31; 25(2):195-200. PubMed ID: 12635522
    [Abstract] [Full Text] [Related]

  • 11. Characterization of chronic glutamate-mediated motor neuron toxicity in organotypic spinal cord culture prepared from ALS model mice.
    Kosuge Y, Sekikawa-Nishida K, Negi H, Ishige K, Ito Y.
    Neurosci Lett; 2009 Apr 24; 454(2):165-9. PubMed ID: 19429077
    [Abstract] [Full Text] [Related]

  • 12. Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals.
    Roux S, Saint Cloment C, Curie T, Girard E, Miana Mena FJ, Barbier J, Osta R, Molgó J, Brûlet P.
    Eur J Neurosci; 2006 Sep 24; 24(6):1546-54. PubMed ID: 17004918
    [Abstract] [Full Text] [Related]

  • 13. Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy.
    Moreno-Igoa M, Calvo AC, Penas C, Manzano R, Oliván S, Muñoz MJ, Mancuso R, Zaragoza P, Aguilera J, Navarro X, Osta Pinzolas R.
    J Mol Med (Berl); 2010 Mar 24; 88(3):297-308. PubMed ID: 19921501
    [Abstract] [Full Text] [Related]

  • 14. Protective effect of supplemental superoxide dismutase on survival of neuronal cells during starvation. Requirement for cytosolic distribution.
    Matthews CC, Figueiredo DM, Wollack JB, Fairweather NF, Dougan G, Hallewell RA, Cadet JL, Fishman PS.
    J Mol Neurosci; 2000 Jun 24; 14(3):155-66. PubMed ID: 10984191
    [Abstract] [Full Text] [Related]

  • 15. Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy.
    Acsadi G, Anguelov RA, Yang H, Toth G, Thomas R, Jani A, Wang Y, Ianakova E, Mohammad S, Lewis RA, Shy ME.
    Hum Gene Ther; 2002 Jun 10; 13(9):1047-59. PubMed ID: 12067438
    [Abstract] [Full Text] [Related]

  • 16. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.
    Thomsen GM, Alkaslasi M, Vit JP, Lawless G, Godoy M, Gowing G, Shelest O, Svendsen CN.
    Gene Ther; 2017 Apr 10; 24(4):245-252. PubMed ID: 28276446
    [Abstract] [Full Text] [Related]

  • 17. GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD-1) gene.
    Derby ML, Giuliano R, Figlewicz DA, Bohn MC.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2000 Mar 10; 1(2):113-22. PubMed ID: 11467048
    [Abstract] [Full Text] [Related]

  • 18. Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture.
    Carunchio I, Curcio L, Pieri M, Pica F, Caioli S, Viscomi MT, Molinari M, Canu N, Bernardi G, Zona C.
    Exp Neurol; 2010 Nov 10; 226(1):218-30. PubMed ID: 20832409
    [Abstract] [Full Text] [Related]

  • 19. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice.
    Holasek SS, Wengenack TM, Kandimalla KK, Montano C, Gregor DM, Curran GL, Poduslo JF.
    Brain Res; 2005 May 31; 1045(1-2):185-98. PubMed ID: 15910777
    [Abstract] [Full Text] [Related]

  • 20. Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis.
    Pitzer C, Krüger C, Plaas C, Kirsch F, Dittgen T, Müller R, Laage R, Kastner S, Suess S, Spoelgen R, Henriques A, Ehrenreich H, Schäbitz WR, Bach A, Schneider A.
    Brain; 2008 Dec 31; 131(Pt 12):3335-47. PubMed ID: 18835867
    [Abstract] [Full Text] [Related]

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