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Journal Abstract Search

211 related items for PubMed ID: 19116265

  • 1. Unbound drug concentration in brain homogenate and cerebral spinal fluid at steady state as a surrogate for unbound concentration in brain interstitial fluid.
    Liu X, Van Natta K, Yeo H, Vilenski O, Weller PE, Worboys PD, Monshouwer M.
    Drug Metab Dispos; 2009 Apr; 37(4):787-93. PubMed ID: 19116265
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  • 2. Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats.
    Nagaya Y, Nozaki Y, Takenaka O, Watari R, Kusano K, Yoshimura T, Kusuhara H.
    Drug Metab Pharmacokinet; 2016 Feb; 31(1):57-66. PubMed ID: 26830080
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  • 3. Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentration.
    Liu X, Smith BJ, Chen C, Callegari E, Becker SL, Chen X, Cianfrogna J, Doran AC, Doran SD, Gibbs JP, Hosea N, Liu J, Nelson FR, Szewc MA, Van Deusen J.
    Drug Metab Dispos; 2006 Sep; 34(9):1443-7. PubMed ID: 16760229
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  • 5. An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.
    Doran AC, Osgood SM, Mancuso JY, Shaffer CL.
    Drug Metab Dispos; 2012 Nov; 40(11):2162-73. PubMed ID: 22899853
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  • 12. Estimation of the unbound brain concentration of P-glycoprotein substrates or nonsubstrates by a serial cerebrospinal fluid sampling technique in rats.
    Mariappan TT, Kurawattimath V, Gautam SS, Kulkarni CP, Kallem R, Taskar KS, Marathe PH, Mandlekar S.
    Mol Pharm; 2014 Feb 03; 11(2):477-85. PubMed ID: 24380373
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  • 14. Use of Subcutaneous and Intraperitoneal Administration Methods to Facilitate Cassette Dosing in Microdialysis Studies in Rats.
    Durk MR, Deshmukh G, Valle N, Ding X, Liederer BM, Liu X.
    Drug Metab Dispos; 2018 Jul 03; 46(7):964-969. PubMed ID: 29700231
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  • 19. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics.
    Shen DD, Artru AA, Adkison KK.
    Adv Drug Deliv Rev; 2004 Oct 14; 56(12):1825-57. PubMed ID: 15381336
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