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457 related items for PubMed ID: 19117642

  • 1. Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
    López Cara LC, Camacho ME, Carrión MD, Tapias V, Gallo MA, Escames G, Acuña-Castroviejo D, Espinosa A, Entrena A.
    Eur J Med Chem; 2009 Jun; 44(6):2655-66. PubMed ID: 19117642
    [Abstract] [Full Text] [Related]

  • 2. Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III).
    Carrión MD, López Cara LC, Camacho ME, Tapias V, Escames G, Acuña-Castroviejo D, Espinosa A, Gallo MA, Entrena A.
    Eur J Med Chem; 2008 Nov; 43(11):2579-91. PubMed ID: 18325637
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group.
    Carrión MD, Chayah M, Entrena A, López A, Gallo MA, Acuña-Castroviejo D, Camacho ME.
    Bioorg Med Chem; 2013 Jul 15; 21(14):4132-42. PubMed ID: 23735830
    [Abstract] [Full Text] [Related]

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  • 5. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030
    [Abstract] [Full Text] [Related]

  • 6. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2003 Apr 24; 46(9):1661-9. PubMed ID: 12699384
    [Abstract] [Full Text] [Related]

  • 7. Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOS dimerization inhibitors that are orally active in pain models.
    Payne JE, Bonnefous C, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND.
    J Med Chem; 2010 Nov 11; 53(21):7739-55. PubMed ID: 20931971
    [Abstract] [Full Text] [Related]

  • 8. 4,5-dihydro-1H-pyrazole derivatives with inhibitory nNOS activity in rat brain: synthesis and structure-activity relationships.
    Camacho ME, León J, Entrena A, Velasco G, Carrión MD, Escames G, Vivó A, Acuña-Castroviejo D, Gallo MA, Espinosa A.
    J Med Chem; 2004 Nov 04; 47(23):5641-50. PubMed ID: 15509163
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of indazole derivatives.
    Claramunt RM, López C, López A, Pérez-Medina C, Pérez-Torralba M, Alkorta I, Elguero J, Escames G, Acuña-Castroviejo D.
    Eur J Med Chem; 2011 Apr 04; 46(4):1439-47. PubMed ID: 21334118
    [Abstract] [Full Text] [Related]

  • 10. Melatonin synthetic analogs as nitric oxide synthase inhibitors.
    Camacho ME, Carrion MD, Lopez-Cara LC, Entrena A, Gallo MA, Espinosa A, Escames G, Acuna-Castroviejo D.
    Mini Rev Med Chem; 2012 Jun 04; 12(7):600-17. PubMed ID: 22512552
    [Abstract] [Full Text] [Related]

  • 11. 4,5-dialkylsubstituted 2-imino-1,3-thiazolidine derivatives as potent inducible nitric oxide synthase inhibitors.
    Ueda S, Terauchi H, Yano A, Matsumoto M, Kubo T, Kyoya Y, Suzuki K, Ido M, Kawasaki M.
    Bioorg Med Chem; 2004 Aug 01; 12(15):4101-16. PubMed ID: 15246088
    [Abstract] [Full Text] [Related]

  • 12. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors.
    Chayah M, Carrión MD, Gallo MA, Jiménez R, Duarte J, Camacho ME.
    ChemMedChem; 2015 May 01; 10(5):874-82. PubMed ID: 25801086
    [Abstract] [Full Text] [Related]

  • 13. Kynurenamines as neural nitric oxide synthase inhibitors.
    Entrena A, Camacho ME, Carrión MD, López-Cara LC, Velasco G, León J, Escames G, Acuña-Castroviejo D, Tapias V, Gallo MA, Vivó A, Espinosa A.
    J Med Chem; 2005 Dec 29; 48(26):8174-81. PubMed ID: 16366599
    [Abstract] [Full Text] [Related]

  • 14. 1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
    Renton P, Speed J, Maddaford S, Annedi SC, Ramnauth J, Rakhit S, Andrews J.
    Bioorg Med Chem Lett; 2011 Sep 15; 21(18):5301-4. PubMed ID: 21813276
    [Abstract] [Full Text] [Related]

  • 15. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
    Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R.
    Mol Pharmacol; 2006 Jan 15; 69(1):328-37. PubMed ID: 16223957
    [Abstract] [Full Text] [Related]

  • 16. 1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation.
    Wei RG, Adler M, Davey D, Ho E, Mohan R, Polokoff M, Tseng JL, Whitlow M, Xu W, Yuan S, Phillips G.
    Bioorg Med Chem Lett; 2007 May 01; 17(9):2499-504. PubMed ID: 17368901
    [Abstract] [Full Text] [Related]

  • 17. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
    [Abstract] [Full Text] [Related]

  • 18. Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation.
    Claramunt RM, López C, Pérez-Medina C, Pérez-Torralba M, Elguero J, Escames G, Acuña-Castroviejo D.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6180-7. PubMed ID: 19679481
    [Abstract] [Full Text] [Related]

  • 19. Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors attenuates fever due to LPS in rats.
    Soszynski D, Chelminiak M.
    J Physiol Pharmacol; 2007 Sep 01; 58(3):551-61. PubMed ID: 17928650
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
    Castaño T, Encinas A, Pérez C, Castro A, Campillo NE, Gil C.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6193-206. PubMed ID: 18477512
    [Abstract] [Full Text] [Related]

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