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Journal Abstract Search

116 related items for PubMed ID: 19128969

  • 1. Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor.
    Witherington J, Abberley L, Bellenie BR, Boatman R, Collis K, Dean DK, Gaiba A, King NP, Shuker N, Steadman JG, Takle AK, Sanger G, Butler S, McKay F, Muir A, Winborn K, Ward RW, Heightman TD.
    Bioorg Med Chem Lett; 2009 Feb 01; 19(3):684-7. PubMed ID: 19128969
    [Abstract] [Full Text] [Related]

  • 2. Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
    Witherington J, Abberley L, Briggs MA, Collis K, Dean DK, Gaiba A, King NP, Kraus H, Shuker N, Steadman JG, Takle AK, Sanger G, Wadsworth G, Butler S, McKay F, Muir A, Winborn K, Heightman TD.
    Bioorg Med Chem Lett; 2008 Mar 15; 18(6):2203-5. PubMed ID: 18316188
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists.
    Zhao H, Xin Z, Patel JR, Nelson LT, Liu B, Szczepankiewicz BG, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL, Liu G.
    Bioorg Med Chem Lett; 2005 Apr 01; 15(7):1825-8. PubMed ID: 15780615
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  • 5. Highly potent growth hormone secretagogues.
    Lu Z, Tata JR, Cheng K, Wei L, Chan WW, Butler B, Schleim KD, Jacks TM, Hickey G, Patchett AA.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3657-9. PubMed ID: 17482461
    [Abstract] [Full Text] [Related]

  • 6. Ghrelin receptor modulators and their therapeutic potential.
    Costantino L, Barlocco D.
    Future Med Chem; 2009 Apr 01; 1(1):157-77. PubMed ID: 21426074
    [Abstract] [Full Text] [Related]

  • 7. Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.
    Pasternak A, Goble SD, deJesus RK, Hreniuk DL, Chung CC, Tota MR, Mazur P, Feighner SD, Howard AD, Mills SG, Yang L.
    Bioorg Med Chem Lett; 2009 Nov 01; 19(21):6237-40. PubMed ID: 19767208
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  • 9. The discovery and optimisation of benzazepine sulfonamide and sulfones as potent agonists of the motilin receptor.
    Bailey JM, Scott JS, Basilla JB, Bolton VJ, Boyfield I, Evans DG, Fleury E, Heightman TD, Jarvie EM, Lawless K, Matthews KL, McKay F, Mok H, Muir A, Orlek BS, Sanger GJ, Stemp G, Stevens AJ, Thompson M, Ward J, Vaidya K, Westaway SM.
    Bioorg Med Chem Lett; 2009 Nov 15; 19(22):6452-8. PubMed ID: 19804969
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  • 10. Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists.
    Hilfiker MA, Wang N, Hou X, Du Z, Pullen MA, Nord M, Nagilla R, Fries HE, Wu CW, Sulpizio AC, Jaworski JP, Morrow D, Edwards RM, Jin J.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4292-5. PubMed ID: 19487124
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  • 12. Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.
    Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1201-4. PubMed ID: 15686942
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  • 13. Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands.
    Lavey BJ, Kozlowski JA, Shankar BB, Spitler JM, Zhou G, Yang DY, Shu Y, Wong MK, Wong SC, Shih NY, Wu J, McCombie SW, Rizvi R, Wolin RL, Lunn CA.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3760-4. PubMed ID: 17466519
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  • 15. Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
    Xin Z, Serby MD, Zhao H, Kosogof C, Szczepankiewicz BG, Liu M, Liu B, Hutchins CW, Sarris KA, Hoff ED, Falls HD, Lin CW, Ogiela CA, Collins CA, Brune ME, Bush EN, Droz BA, Fey TA, Knourek-Segel VE, Shapiro R, Jacobson PB, Beno DW, Turner TM, Sham HL, Liu G.
    J Med Chem; 2006 Jul 27; 49(15):4459-69. PubMed ID: 16854051
    [Abstract] [Full Text] [Related]

  • 16. Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity.
    Yu M, Lizarzaburu M, Beckmann H, Connors R, Dai K, Haller K, Li C, Liang L, Lindstrom M, Ma J, Motani A, Wanska M, Zhang A, Li L, Medina JC.
    Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1758-62. PubMed ID: 20137933
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.
    Demange L, Boeglin D, Moulin A, Mousseaux D, Ryan J, Bergé G, Gagne D, Heitz A, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J.
    J Med Chem; 2007 Apr 19; 50(8):1939-57. PubMed ID: 17375904
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  • 18. 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs.
    Kai H, Morioka Y, Koriyama Y, Okamoto K, Hasegawa Y, Hattori M, Koike K, Chiba H, Shinohara S, Iwamoto Y, Takahashi K, Tanimoto N.
    Bioorg Med Chem Lett; 2008 Dec 15; 18(24):6444-7. PubMed ID: 18977140
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  • 20. Small, non-peptide C5a receptor antagonists: part 1.
    Blagg J, Mowbray C, Pryde DC, Salmon G, Schmid E, Fairman D, Beaumont K.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5601-4. PubMed ID: 18809326
    [Abstract] [Full Text] [Related]

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